2008 Medicinal Chemistry DiVision Award Address ML Mohler, CE Bohl, A Jones, CC Coss, R Narayanan, Y He, DJ Hwang, ... | | |
A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer S Ahn, DJ Hwang, CM Barrett, J Yang, CB Duke, DD Miller, JT Dalton Cancer chemotherapy and pharmacology 67, 293-304, 2011 | 30 | 2011 |
A potent, metabolically stable tubulin inhibitor targets the colchicine binding site and overcomes taxane resistance KE Arnst, Y Wang, DJ Hwang, Y Xue, T Costello, D Hamilton, Q Chen, ... Cancer research 78 (1), 265-277, 2018 | 113 | 2018 |
A selective androgen receptor modulator for hormonal male contraception J Chen, DJ Hwang, CE Bohl, DD Miller, JT Dalton Journal of Pharmacology and Experimental Therapeutics 312 (2), 546-553, 2005 | 125 | 2005 |
Abstract B037: Potential next-generation androgen receptor-targeted therapeutic for enzalutamide-resistant prostate cancer; In vivo characterization in immune … SU Ponnusamy, FK Noto, BT Adedeji, Y He, DJ Hwang, S Moody, ... Molecular Cancer Therapeutics 18 (12_Supplement), B037-B037, 2019 | | 2019 |
Abstract# 3326: In vitro and in vivo studies of novel indoles that exert antimitotic activity in prostate cancer and multidrug-resistant tumor cells with less neurotoxicity. S Ahn, C Duke, DJ Hwang, D Miller, J Dalton Cancer Research 69 (9_Supplement), 3326-3326, 2009 | | 2009 |
Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics W Effah, M Khalil, DJ Hwang, DD Miller, R Narayanan Steroids, 109486, 2024 | | 2024 |
An overview of next-generation androgen receptor-targeted therapeutics in development for the treatment of prostate cancer ML Mohler, A Sikdar, S Ponnusamy, DJ Hwang, Y He, DD Miller, ... International journal of molecular sciences 22 (4), 2124, 2021 | 54 | 2021 |
Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding KM Maize, EK Kurbanov, D La Mora-Rey, TW Geders, DJ Hwang, ... Acta Crystallographica Section D: Biological Crystallography 70 (11), 2813-2822, 2014 | 26 | 2014 |
Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer DJ Hwang, J Yang, H Xu, IM Rakov, ML Mohler, JT Dalton, DD Miller Bioorganic & medicinal chemistry 14 (19), 6525-6538, 2006 | 53 | 2006 |
Cellular hormone metabolism is critical for canonical androgen receptor antagonist activity R Narayanan, S Ponnusamy, W Effah, T Thiyagarajan, DJ Hwang, Y He, ... European Journal of Cancer 174, S105, 2022 | | 2022 |
Colchicine binding site agent DJ95 overcomes drug resistance and exhibits antitumor efficacy KE Arnst, Y Wang, ZN Lei, DJ Hwang, G Kumar, D Ma, DN Parke, Q Chen, ... Molecular Pharmacology 96 (1), 73-89, 2019 | 28 | 2019 |
Computationally identified novel agonists for GPRC6A M Pi, K Kapoor, R Ye, DJ Hwang, DD Miller, JC Smith, J Baudry, ... PloS one 13 (4), e0195980, 2018 | 19 | 2018 |
Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy KE Arnst, S Banerjee, H Chen, S Deng, DJ Hwang, W Li, DD Miller Medicinal research reviews 39 (4), 1398-1426, 2019 | 127 | 2019 |
Current advances of tubulin inhibitors in nanoparticle drug delivery and vascular disruption/angiogenesis S Banerjee, DJ Hwang, W Li, DD Miller Molecules 21 (11), 1468, 2016 | 58 | 2016 |
Dicaffeoyl-or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors DJ Hwang, SN Kim, JH Choi, YS Lee Bioorganic & medicinal chemistry 9 (6), 1429-1437, 2001 | 81 | 2001 |
Discovery and Characterization of Selective Degraders of Full Length and Splice Variant Androgen Receptors (SARDs) for the Treatment of Advanced Prostate Cancer S Ponnusamy, RH Getzenberg, L Selth, T Thiyagarajan, DJ Hwang, Y He, ... 99th Annual Meeting of the Endocrine Society, 2017 | | 2017 |
Discovery of first-in-class mitogen activated protein kinase (MAPK) 8–10 activator for the treatment of high grade serous ovarian cancer (1287) A Masri, B Wilson, P Blackburn, A Martin, S Asemota, DJ Hwang, D Miller, ... Gynecologic Oncology 176, S179-S180, 2023 | | 2023 |
DJ-X-013 ameliorates inflammation by reducing TNF-α/NF-κB expression and experimental colitis by inducing myeloid-derived suppressor cells M Mandal, A Rakib, S Kiran, DJ Hwang, W Li, DD Miller, UP Singh The Journal of Immunology 210 (1_Supplement), 61.06-61.06, 2023 | | 2023 |
DJ-X-013 Reduces LPS-Induced Inflammation, Modulates Th17/Myeloid-Derived Suppressor Cells, and Alters NF-kB Expression to Ameliorate Experimental Colitis M Mandal, A Rakib, MA Al Mamun, S Kumar, F Park, DJ Hwang, W Li, ... Modulates Th17/Myeloid-Derived Suppressor Cells, and Alters NF-kB Expression …, 0 | | |