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Mark Donowitz
Mark Donowitz
Professor of Medicine and Physiology, Johns Hopkins University School of Medicine
在 jhmi.edu 的电子邮件经过验证
标题
引用次数
年份
" Abbreviation: NHE, Na'/H'exchanger isoform.
SA Levine, J Pouyssegur, CM Tse, M Donowitz
1993
[Ca2+] i independent mitogenesis in cultured human fibroblasts revealed by single cell microfluorimetry
FC Praeger, L Reinlib, M Donowitz, BA Gilchrest
Biochemical and biophysical research communications 159 (2), 862-870, 1989
21989
1014 SRC Dynamically Associates With PLC-γ and is Necessary for CA2+-Mediated Inhibition of NHE3 Activity in CACO-2/BBE Cells
NC Zachos, X Li, LJ Lee, M Donowitz
Gastroenterology 5 (138), S-147, 2010
2010
1015 A Novel Ser-Rich Motif in the NHE3 C-Terminal Regulatory Domain is Required for Stimulation of Na/H Exchange Activity by AKT as Well as for Direct Ezrin Binding to NHE3
R Lin, B Cha, M Chakraborty, S Mohan, M Donowitz
Gastroenterology 5 (138), S-147, 2010
2010
110 Missense Mutations of SLC9A3 in Patients With Congenital Sodium Diarrhea Are Associated With Reduced Na+/H+ Exchanger 3 (NHE3) Activity: Identification of the Cause of the …
J Yin, R Sarker, J Yang, P Heinz-Erian, T Müller, H Zoller, M Tse, ...
Gastroenterology 148 (4), S-29, 2015
32015
189 Basal and Stimulated BB NHE3 Activity Requires Intracellular SNX27, a PDZDomain Containing Binding Partner of NHE3 That Regulates Endosome to Plasma Membrane Trafficking
V Singh, J Yang, R Sarker, T Chen, B Cha, NC Zachos, M Donowitz
Gastroenterology 5 (146), S-50, 2014
2014
190 Human Small Intestinal Enteroids Enable Mechanistic Studies of cAMPInduced Changes in Intracellular pH
J Foulke-Abel, J In, NC Zachos, O Kovbasnjuk, K Ettayebi, H de Jonge, ...
Gastroenterology 5 (146), S-50, 2014
12014
23-Human Colonoid Regeneration is Guided by Desert Hedgehog and WNT2B after Injury by Enterohemorrhagic E. Coli (EHEC) Secreted Serine Protease ESPP
J In, J Yin, W Xie, R Cole, NC Zachos, M Donowitz, H Easwaran, ...
Gastroenterology 154 (6), S-7-S-8, 2018
2018
256 Myosin VI is Responsible for Movement of NHE3 From the Microvillus of Polarized Caco-2-bbe Cells to the Intervillus Clefts Under Basal Conditions and With Ca2+ Stimulated …
T Chen, R Sarker, CT Ming, O Kovbasnjuk, A Hubbard, M Donowitz
Gastroenterology 5 (138), S-47, 2010
2010
266 NHE3 IS A DRUG TARGET FOR TREATING DIARRHE; A NOVEL PEPTIDE STIMULATES NHE3 ACTIVITY, PREVENTS CAMP, CGMP AND CA2+ INHIBITION OF NHE3 AND PREVENTS CHOLERA TOXIN AND E. COLI …
NC Zachos, R Sarker, R Lin, CM Tse, JJ Green, M Donowitz
Gastroenterology 160 (6), S-63-S-64, 2021
12021
269-A Novel Model of Human Enteroids in the Intestine-Chip (IC) Platform that Includes Dynamic Flow and Cyclic Strain for Physiological and Phamacological Studies of Intestinal …
J Yin, L Sunuwar, MJ Kasendra, H Yu, M Sun, M Tse, P Haggie, ...
Gastroenterology 154 (6), S-66, 2018
2018
27 Neutral Na+ Absorption and Fluid/Anion Secretion Are Not Separated Processes in the Human Enteroid Model
J Foulke-Abel, J In, NC Zachos, O Kovbasnjuk, M Donowitz
Gastroenterology 148 (4), S-9, 2015
2015
31–Endosomal Snx17 Sets the Plasma Membrane Amount of Nhe3 and Prevents Its Degradation by Binding to the Nhe3 Cterminus
V Singh, J Yang, J Yin, M Tse, M Donowitz
Gastroenterology 156 (6), S-13, 2019
2019
34 Human Intestinal Epithelial Response to Gastrointestinal Virus Infection Using Enteroids
SE Blutt, K Saxena, SE Crawford, JR Broughman, ME Conner, K Ettayebi, ...
Gastroenterology 148 (4), S-10-S-11, 2015
2015
34–E. Coli Heat Stable Enterotoxin (ST) Inhibition of Nhe3 Occurs by Different Signaling Pathways Downstream of Cyclic Gmp in Murine Jejunum and Caco-2 Cells: A Warning About …
M Donowitz, T Chen, R Lin, R Sarker, B Cha, LR Avula, M Tse
Gastroenterology 156 (6), S-14, 2019
2019
35-Anion Secretion is Quantitatively Rather than Qualitatively Different Between Crypt-Like Undifferentiated and Villuslike Differentiated Human Duodenal Enteroid Monolayers
J Yin, M Tse, LR Avula, V Singh, H de Jonge, M Donowitz
Gastroenterology 154 (6), S-11-S-12, 2018
2018
4 A Peptide Mimicking the NHE3 C-Terminus Stimulates Basal and Blocks CA2+ and cAMP Inhibition of NHE3 Activity, and Prevents Cholera Toxin-Induced Mouse Jejunal Fluid …
NC Zachos, DB van Rossum, R Murtazina, M Chakraborty, RL Patterson, ...
Gastroenterology 5 (142), S-1, 2012
42012
4 To whom correspondence should be addressed: Division of Gastroenterology and Hepatology, Dept. of Medicine, 925 Ross Research Bldg., Johns Hopkins University School of …
J Yang, V Singh, B Cha, TE Chen, R Sarker, R Murtazina, S Jin, ...
2013
401 Human Ex Vivo Enteroid Culture As a Functional Model of Human Small Intestinal Physiology and Pathophysiology: Inhibition of Na+ Absorption by cAMP and Rotavirus and …
NC Zachos, J In, J Foulke-Abel, S Middendorp, H de Jonge, XL Zeng, ...
Gastroenterology 5 (144), S-78, 2013
2013
430-Epithelial-Secreted WNT Ligands are Essential Drivers of Intestinal Stem Cell Response to Virus-Induced Villus Damage
WY Zou, SE Blutt, XL Zeng, MS Chen, YH Lo, D Castillo-Azofeifa, OD Kein, ...
Gastroenterology 154 (6), S-96, 2018
22018
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