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Hojong Yoon
Hojong Yoon
Broad Institute of MIT and Harvard
在 broadinstitute.org 的电子邮件经过验证
标题
引用次数
年份
2, 3, 5-substituted thiophene compound as protein kinase inhibitor
TB Sim, WY Hur, C man Song, HJ Yoon, SH Choi, HN Cho, HG Choi, ...
US Patent 10,442,796, 2019
22019
4-((2-acrylamidophenyl) amino) thieno [3, 2-D] pyrimidine-7-carboxamide derivatives as protein kinase inhibitors
TB Sim, HJ Yoon, IJ Shin, YJ Nam, HG Choi
US Patent 10,040,803, 2018
2018
A pyrazolo [3, 4-d] pyrimidin-4-amine derivative containing an isoxazole moiety is a selective and potent inhibitor of RET gatekeeper mutants
H Yoon*, Y Kwak*, S Choi, H Cho, ND Kim, T Sim
Journal of medicinal chemistry 59 (1), 358-373, 2016
312016
Asymmetric synthesis of (+)-lentiginosine using a chiral aziridine based approach
H Yoon, KS Cho, T Sim
Tetrahedron: Asymmetry 25 (6-7), 497-502, 2014
192014
Asymmetric Synthesis of (−)-6-Desmethyl-Fluvirucinine A1 Via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions
H Moon*, H Yoon*, C Lim, J Jang, JJ Yi, JK Lee, J Lee, Y Na, WS Son, ...
Molecules 23 (9), 2351, 2018
42018
BTBBCL6 dimers as building blocks for reversible drug-induced protein oligomerization
L Nitsch, P Jensen, H Yoon, J Koeppel, SSR Burman, ES Fischer, ...
Cell Reports Methods 2 (4), 2022
72022
Chemically inducible polypeptide polymerization
B Ebert, M Slabicki, ES Fischer, H Yoon, J Koeppel
US Patent App. 17/750,061, 2022
2022
CML therapeutic agents with reduced drug-resistance and side-effect comprising 1, 6-disubstituted indole compounds
TB Sim, HJ Yoon, WY Hur, YJ Nam, HG Choi
US Patent 10,130,631, 2018
2018
Double blockade of glioma cell proliferation and migration by temozolomide conjugated with NPPB, a chloride channel blocker
M Park, C Song, H Yoon, KH Choi
ACS Chemical Neuroscience 7 (3), 275-285, 2016
182016
Elucidating the Mechanism of Small-molecule-induced Protein Degradation for Targeted Cancer Therapy
H Yoon
Harvard University, 2021
2021
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
G Du, J Jiang, NJ Henning, N Safaee, E Koide, RP Nowak, KA Donovan, ...
Cell chemical biology 29 (10), 1470-1481. e31, 2022
402022
Heteroarylamine derivatives as protein kinase inhibitors
TB Sim, HJ Yoon, JH Yoon, WY Hur, EJ Roh, YU Kwak
US Patent 9,586,936, 2017
112017
Hidtil ukendt 2, 3, 5-substitueret thiophenforbindelse som proteinkinasehæmmer
TB Sim, WY Hur, CM Song, HJ Yoon, SH Choi, HN Cho, HG Choi, ND Kim, ...
2021
Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor
H Yoon*, I Shin*, Y Nam, ND Kim, KB Lee, T Sim
European journal of medicinal chemistry 125, 1145-1155, 2017
202017
Identification of novel resorcinol amide derivatives as potent and specific pyruvate dehydrogenase kinase (PDHK) inhibitors
H Cho, I Shin, K Cho, H Yoon, EK Yoo, MJ Kim, S Park, IK Lee, ND Kim, ...
Journal of Medicinal Chemistry 62 (18), 8461-8479, 2019
72019
Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach
A Nonami, M Sattler, E Weisberg, Q Liu, J Zhang, MP Patricelli, ...
Blood, The Journal of the American Society of Hematology 125 (20), 3133-3143, 2015
312015
Identification of Thieno [3, 2-d] pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3
H Cho*, I Shin*, H Yoon*, E Jeon, J Lee, Y Kim, SS Ryu, C Song, ...
Journal of Medicinal Chemistry, 2021
172021
In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3
G Hwang, H Kim, H Yoon, C Song, DK Lim, T Sim, J Lee
International Journal of Nanomedicine, 5345-5357, 2017
52017
Induced protein degradation for therapeutics: past, present, and future
H Yoon, JC Rutter, YD Li, BL Ebert
The Journal of Clinical Investigation 134 (1), 2024
42024
Novel 2, 3, 5-substituted thiophene compound as protein kinase inhibitor
YK Ko, SY Lee, SK Yoon, JH Bae, TB Sim, WY Hur, CM Song, HJ Yoon, ...
2019
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