2, 3, 5-substituted thiophene compound as protein kinase inhibitor TB Sim, WY Hur, C man Song, HJ Yoon, SH Choi, HN Cho, HG Choi, ... US Patent 10,442,796, 2019 | 2 | 2019 |
4-((2-acrylamidophenyl) amino) thieno [3, 2-D] pyrimidine-7-carboxamide derivatives as protein kinase inhibitors TB Sim, HJ Yoon, IJ Shin, YJ Nam, HG Choi US Patent 10,040,803, 2018 | | 2018 |
A pyrazolo [3, 4-d] pyrimidin-4-amine derivative containing an isoxazole moiety is a selective and potent inhibitor of RET gatekeeper mutants H Yoon*, Y Kwak*, S Choi, H Cho, ND Kim, T Sim Journal of medicinal chemistry 59 (1), 358-373, 2016 | 31 | 2016 |
Asymmetric synthesis of (+)-lentiginosine using a chiral aziridine based approach H Yoon, KS Cho, T Sim Tetrahedron: Asymmetry 25 (6-7), 497-502, 2014 | 19 | 2014 |
Asymmetric Synthesis of (−)-6-Desmethyl-Fluvirucinine A1 Via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions H Moon*, H Yoon*, C Lim, J Jang, JJ Yi, JK Lee, J Lee, Y Na, WS Son, ... Molecules 23 (9), 2351, 2018 | 4 | 2018 |
BTBBCL6 dimers as building blocks for reversible drug-induced protein oligomerization L Nitsch, P Jensen, H Yoon, J Koeppel, SSR Burman, ES Fischer, ... Cell Reports Methods 2 (4), 2022 | 7 | 2022 |
Chemically inducible polypeptide polymerization B Ebert, M Slabicki, ES Fischer, H Yoon, J Koeppel US Patent App. 17/750,061, 2022 | | 2022 |
CML therapeutic agents with reduced drug-resistance and side-effect comprising 1, 6-disubstituted indole compounds TB Sim, HJ Yoon, WY Hur, YJ Nam, HG Choi US Patent 10,130,631, 2018 | | 2018 |
Double blockade of glioma cell proliferation and migration by temozolomide conjugated with NPPB, a chloride channel blocker M Park, C Song, H Yoon, KH Choi ACS Chemical Neuroscience 7 (3), 275-285, 2016 | 18 | 2016 |
Elucidating the Mechanism of Small-molecule-induced Protein Degradation for Targeted Cancer Therapy H Yoon Harvard University, 2021 | | 2021 |
Exploring the target scope of KEAP1 E3 ligase-based PROTACs G Du, J Jiang, NJ Henning, N Safaee, E Koide, RP Nowak, KA Donovan, ... Cell chemical biology 29 (10), 1470-1481. e31, 2022 | 40 | 2022 |
Heteroarylamine derivatives as protein kinase inhibitors TB Sim, HJ Yoon, JH Yoon, WY Hur, EJ Roh, YU Kwak US Patent 9,586,936, 2017 | 11 | 2017 |
Hidtil ukendt 2, 3, 5-substitueret thiophenforbindelse som proteinkinasehæmmer TB Sim, WY Hur, CM Song, HJ Yoon, SH Choi, HN Cho, HG Choi, ND Kim, ... | | 2021 |
Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor H Yoon*, I Shin*, Y Nam, ND Kim, KB Lee, T Sim European journal of medicinal chemistry 125, 1145-1155, 2017 | 20 | 2017 |
Identification of novel resorcinol amide derivatives as potent and specific pyruvate dehydrogenase kinase (PDHK) inhibitors H Cho, I Shin, K Cho, H Yoon, EK Yoo, MJ Kim, S Park, IK Lee, ND Kim, ... Journal of Medicinal Chemistry 62 (18), 8461-8479, 2019 | 7 | 2019 |
Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach A Nonami, M Sattler, E Weisberg, Q Liu, J Zhang, MP Patricelli, ... Blood, The Journal of the American Society of Hematology 125 (20), 3133-3143, 2015 | 31 | 2015 |
Identification of Thieno [3, 2-d] pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3 H Cho*, I Shin*, H Yoon*, E Jeon, J Lee, Y Kim, SS Ryu, C Song, ... Journal of Medicinal Chemistry, 2021 | 17 | 2021 |
In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3 G Hwang, H Kim, H Yoon, C Song, DK Lim, T Sim, J Lee International Journal of Nanomedicine, 5345-5357, 2017 | 5 | 2017 |
Induced protein degradation for therapeutics: past, present, and future H Yoon, JC Rutter, YD Li, BL Ebert The Journal of Clinical Investigation 134 (1), 2024 | 4 | 2024 |
Novel 2, 3, 5-substituted thiophene compound as protein kinase inhibitor YK Ko, SY Lee, SK Yoon, JH Bae, TB Sim, WY Hur, CM Song, HJ Yoon, ... | | 2019 |