A chaperone pathway in protein disaggregation: Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104 AG Cashikar, M Duennwald, SL Lindquist Journal of Biological Chemistry 280 (25), 23869-23875, 2005 | 375 | 2005 |
A chaperone pathway in protein disaggregation: Hsp26 ALTERS THE NATURE OF PROTEIN AGGREGATES TO FACILITATE REACTIVATION BY Hsp104. VOLUME 280 (2005) PAGES 23869-23875 AG Cashikar, M Duennwald, SL Lindquist Journal of Biological Chemistry 281 (13), 8996, 2006 | 2 | 2006 |
A functional unfolded protein response is required for chronological aging in Saccharomyces cerevisiae SR Chadwick, EN Fazio, P Etedali-Zadeh, J Genereaux, ML Duennwald, ... Current Genetics 66, 263-277, 2020 | 15 | 2020 |
A network of protein interactions determines polyglutamine toxicity ML Duennwald, S Jagadish, F Giorgini, PJ Muchowski, S Lindquist Proceedings of the National Academy of Sciences 103 (29), 11051-11056, 2006 | 175 | 2006 |
A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90 V Ngo, A Brickenden, H Liu, C Yeung, WY Choy, ML Duennwald Disease Models & Mechanisms 15 (4), dmm049235, 2022 | 5 | 2022 |
A quantitative imaging-based protocol for yeast growth and survival on agar plates AA Petropavlovskiy, MG Tauro, P Lajoie, ML Duennwald STAR protocols 1 (3), 100182, 2020 | 44 | 2020 |
A subset of calcium‐binding S100 proteins show preferential heterodimerization DE Spratt, KR Barber, NM Marlatt, V Ngo, JA Macklin, Y Xiao, ... The FEBS journal 286 (10), 1859-1876, 2019 | 18 | 2019 |
A synergistic small-molecule combination directly eradicates diverse prion strain structures BE Roberts, ML Duennwald, H Wang, C Chung, NP Lopreiato, ... Nature chemical biology 5 (12), 936-946, 2009 | 115 | 2009 |
A Toolbox for Rapid Quantitative Assessment of Chronological Lifespan and Survival in Saccharomyces cerevisiae SR Chadwick, AD Pananos, SE Di Gregorio, AE Park, P Etedali‐Zadeh, ... Traffic 17 (6), 689-703, 2016 | 21 | 2016 |
A toolbox of fluorescent assays to assess chronological lifespan in Saccharomyces cerevisiae SR Chadwick, EJ Park, AD Pananos, ML Duennwald, P Lajoie MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
A yeast model of the ALS protein Matrin3 uncovers Hsp90 and its co-chaperone Sti1 as modifiers of misfolding and toxicity SE Di Gregorio, M Esmaeili, A Salem, ML Duennwald bioRxiv, 2021.08. 24.457481, 2021 | | 2021 |
ALS yeast models—past success stories and new opportunities SE Di Gregorio, ML Duennwald Frontiers in Molecular Neuroscience 11, 394, 2018 | 28 | 2018 |
Assessing the role of endoplasmic stress signaling pathways in chronological aging SR Chadwick, EN Fazio, P Lajoie, ML Duennwald MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
CAG expansions are genetically stable and form nontoxic aggregates in cells lacking endogenous polyglutamine proteins AA Zurawel, R Kabeche, SE DiGregorio, L Deng, KM Menon, H Opalko, ... MBio 7 (5), 10.1128/mbio. 01367-16, 2016 | 11 | 2016 |
Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity MD Leach, TH Kim, SE DiGregorio, C Collins, Z Zhang, ML Duennwald, ... G3: Genes, Genomes, Genetics 7 (1), 95-108, 2017 | 8 | 2017 |
Cellular stress responses in protein misfolding diseases ML Duennwald Future science OA 1 (2), FSO42, 2015 | 22 | 2015 |
Chaperone-dependent amyloid assembly protects cells from prion toxicity PM Douglas, S Treusch, HY Ren, R Halfmann, ML Duennwald, ... Proceedings of the National Academy of Sciences 105 (20), 7206-7211, 2008 | 197 | 2008 |
Chaperones and Polyglutamine Expansion Disorders ML Duennwald Heat Shock Proteins and the Brain: Implications for Neurodegenerative …, 2008 | | 2008 |
Comparative analysis of mutant huntingtin binding partners in yeast species Y Zhao, AA Zurawel, NP Jenkins, ML Duennwald, C Cheng, ... Scientific reports 8 (1), 9554, 2018 | 16 | 2018 |
Compositions and methods for treatment of protein misfolding diseases SL Lindquist, M Duennwald US Patent 8,192,986, 2012 | 11 | 2012 |