14-3-3ζ Captures SET in the Cytoplasm, Mediating Tau Pathology and Cognitive Impairments Y Xia, Q Zhang, G Wu, E Wang, M Wang, F Huang, K Zeng, S Vatansever, ... | | 2021 |
A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer’s disease pathologies Y Yao, SS Kang, Y Xia, ZH Wang, X Liu, T Muller, YE Sun, K Ye Brain 144 (6), 1833-1852, 2021 | 23 | 2021 |
Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration JZ Wang, YY Xia, I Grundke-Iqbal, K Iqbal Journal of Alzheimer's disease 33 (s1), S123-S139, 2013 | 613 | 2013 |
ApoE4 activates C/EBPβ/δ-secretase with 27-hydroxycholesterol, driving the pathogenesis of Alzheimer’s disease ZH Wang, Y Xia, P Liu, X Liu, L Edgington-Mitchell, K Lei, SP Yu, ... Progress in neurobiology 202, 102032, 2021 | 32 | 2021 |
BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer’s disease J Bao, M Qin, YAR Mahaman, B Zhang, F Huang, K Zeng, Y Xia, D Ke, ... Proceedings of the National Academy of Sciences 115 (15), 3954-3959, 2018 | 38 | 2018 |
Bacteroides Fragilis in the gut microbiomes of Alzheimer’s disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice Y Xia, Y Xiao, ZH Wang, X Liu, AM Alam, JP Haran, BA McCormick, X Shu, ... Nature Communications 14 (1), 5471, 2023 | 14 | 2023 |
C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer’s disease Y Xia, Z Wang, J Zhang, X Liu, SP Yu, KX Ye, JZ Wang, K Ye, XC Wang Molecular Psychiatry 26 (10), 6002-6022, 2021 | 38 | 2021 |
C/EBPβ mediates NQO1 and GSTP1 anti-oxidative reductases expression in glioblastoma, promoting brain tumor proliferation K Lei, Y Xia, XC Wang, EH Ahn, L Jin, K Ye Redox biology 34, 101578, 2020 | 32 | 2020 |
C/EBPβ/AEP is age-dependently activated in Parkinson’s disease and mediates α-synuclein in the gut and brain H Wang, G Chen, EH Ahn, Y Xia, SS Kang, X Liu, C Liu, MH Han, S Chen, ... npj Parkinson's Disease 9 (1), 1, 2023 | 7 | 2023 |
C/EBPβ/δ-secretase signaling mediates Parkinson’s disease pathogenesis via regulating transcription and proteolytic cleavage of α-synuclein and MAOB Z Wu, Y Xia, Z Wang, S Su Kang, K Lei, X Liu, L Jin, X Wang, L Cheng, ... Molecular Psychiatry 26 (2), 568-585, 2021 | 28 | 2021 |
CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment Q Zhang, Y Xia, Y Wang, Y Shentu, K Zeng, YAR Mahaman, F Huang, ... Frontiers in Molecular Neuroscience 11, 146, 2018 | 36 | 2018 |
Cleavage of GSK‐3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK‐3β activity induced by H2O2 Y Feng, Y Xia, G Yu, X Shu, H Ge, K Zeng, J Wang, X Wang Journal of neurochemistry 126 (2), 234-242, 2013 | 91 | 2013 |
Codonopsis pilosula Polysaccharide Attenuates Tau Hyperphosphorylation and Cognitive Impairments in hTau Infected Mice Q Zhang, Y Xia, H Luo, S Huang, Y Wang, Y Shentu, YAR Mahaman, ... Frontiers in molecular neuroscience 11, 437, 2018 | 55 | 2018 |
Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders W Li, P Wan, J Qiao, Y Liu, Q Peng, Z Zhang, X Shu, Y Xia, B Sun Frontiers in Pharmacology 15, 1372110, 2024 | | 2024 |
Delta-and beta-secretases crosstalk amplifies the amyloidogenic pathway in Alzheimer’s disease Y Xia, ZH Wang, Z Zhang, X Liu, SP Yu, JZ Wang, XC Wang, K Ye Progress in neurobiology 204, 102113, 2021 | 13 | 2021 |
Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies J Xiang, Y Tao, Y Xia, S Luo, Q Zhao, B Li, X Zhang, Y Sun, W Xia, ... Cell 186 (16), 3350-3367. e19, 2023 | 36 | 2023 |
Discovery of sesquiterpene from Youngia japonica with antitumor effect XS Ye, K Lin, XQ Tao, JT Shang, YR Gui, SX Zhu, YY Xia, HF Chen, ... Fitoterapia 174, 105869, 2024 | 2 | 2024 |
Discovery of sesquiterpene lactones with anti-inflammatory effect from Youngia japonica XS Ye, K Lin, CL Leng, YR Gui, SX Zhu, HY Liu, YY Xia, BL Sun, W Liu, ... Journal of Asian Natural Products Research, 1-8, 2024 | | 2024 |
FSH and ApoE4 contribute to Alzheimer’s disease-like pathogenesis via C/EBPβ/δ-secretase in female mice J Xiong, SS Kang, M Wang, Z Wang, Y Xia, J Liao, X Liu, SP Yu, Z Zhang, ... Nature Communications 14 (1), 6577, 2023 | 7 | 2023 |
GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition M Huang, X Tao, J Bao, J Wang, X Gong, L Luo, S Pan, R Yang, Y Gui, ... Life Sciences 346, 122618, 2024 | | 2024 |