155 Normal, but not cystic fibrosis, sputum inhibits pro-inflammatory Orai1 Ca2+ signaling A Goriounova, J Wrennall, A Gaggar, R Tarran Journal of Cystic Fibrosis 22, S82, 2023 | | 2023 |
17 beta-ESTRADIOL (E2) INHIBITS STIM1 AGGREGATION AND CALCIUM INFLUX IN CF AIRWAY EPITHELIAL CELLS H Hartwell, MJ Watson, R Tartan PEDIATRIC PULMONOLOGY, 252-252, 2009 | | 2009 |
171 Abnormal calcium signaling in cystic fibrosis neutrophils is inversely correlated with FEV1 and can be corrected with the Orai1 antagonist ELD607 J Wrennall, A Ghosh, F Sassano, R Tarran Journal of Cystic Fibrosis 22, S90, 2023 | | 2023 |
17B estradiol (E2) inhibits ATP induced increasing of airway surface liquid height via ER-A and P2Y2 pathway H Sun, J Rasmussen, RD Coakley, I Fricks, R Tarran PEDIATRIC PULMONOLOGY, 248-248, 2007 | | 2007 |
17beta-estradiol inhibits calcium-dependent homeostasis of airway surface liquid volume in human cystic fibrosis airway epithelia R Tarran PEDIATRIC PULMONOLOGY, 162-163, 2009 | 1 | 2009 |
17beta-estradiol inhibits phosphorylation of STIM1: implication for store-operated calcium entry and chronic lung diseases JT Sheridan, RC Gilmore, MJ Watson, CB Archer, R Tarran J Biol Chem 288 (47), 33509-18, 2013 | 3 | 2013 |
17β-Estradiol inhibits Ca2+-dependent homeostasis of airway surface liquid volume in human cystic fibrosis airway epithelia RD Coakley, H Sun, LA Clunes, JE Rasmussen, JR Stackhouse, ... The Journal of clinical investigation 118 (12), 4025-4035, 2008 | 128 | 2008 |
17β-Estradiol inhibits phosphorylation of stromal interaction molecule 1 (STIM1) protein: implication for store-operated calcium entry and chronic lung diseases JT Sheridan, RC Gilmore, MJ Watson, CB Archer, R Tarran Journal of Biological Chemistry 288 (47), 33509-33518, 2013 | 40 | 2013 |
18 CFTR modulators increase viral mobility in healthy and cystic fibrosis airway epithelial cells J Wykoff, K Shaffer, A Pitcairn, E Worthington, R Tarran, R Pickles, C Ehre Journal of Cystic Fibrosis 22, S11, 2023 | | 2023 |
21 ELD403 demonstrates anti-viral activity by aggregating respiratory syncytial virus and reducing the free viral load M Biggart, F Sassano, R Tarran Journal of Cystic Fibrosis 22, S12, 2023 | | 2023 |
3 ELD607, a novel Orai1 antagonist, reduces inflammation and clears Burkholderia cepacia complex and multidrug-resistant Pseudomonas aeruginosa from the lungs S Ahmad, F Sassano, R Tarran Journal of Cystic Fibrosis 22, S2, 2023 | | 2023 |
375: Exposure to healthy or cystic fibrosis sputum alters ion transport across human bronchial epithelial cells M Woodall, B Reidel, M Kesimer, R Tarran, D Baines Journal of Cystic Fibrosis 20, S178, 2021 | | 2021 |
383 ELD607 inhibits excessive proinflammatory Ca2+ signaling in cystic fibrosis neutrophils J Wrennall, A Ghosh, S Abdelwahab, F Sassano, R Tarran Journal of Cystic Fibrosis 21, S224-S225, 2022 | | 2022 |
389 Toxicology of ELD607, a novel immunomodulator of inflammatory responses in cystic fibrosis lungs S Ahmad, M Sassano, J Wrennall, R Tarran Journal of Cystic Fibrosis 21, S227, 2022 | | 2022 |
398: Host and pathogens contribute to decreased host defense protein SPLUNC1 in cystic fibrosis J Zielonka, S Khanal, M Webster, N Shiner, A Carpio, R Tarran, L Sharma, ... Journal of Cystic Fibrosis 20, S188, 2021 | | 2021 |
450 Pro-inflammatory Orai1 activity is elevated in people with cystic fibrosis regardless of elexacaftor/tezacaftor/ivacaftor treatment A Goriounova, R Gilmore, J Wrennall, R Tarran Journal of Cystic Fibrosis 21, S258, 2022 | | 2022 |
498 Cystic fibrosis transmembrane conductance regulator modulator therapy increases viral mobility in primary cystic fibrosis airway cultures infected with respiratory … K Shaffer, J Wykoff, K Araba, E Worthington, R Tarran, R Pickles, C Ehre Journal of Cystic Fibrosis 21, S281-S282, 2022 | | 2022 |
530: Novel immunomodulator ELD607 reduces neutrophilic inflammation in βENaC and Pseudomonas aeruginosa–infected mice S Ahmad, M Sassano, A Ghosh, R Tarran Journal of Cystic Fibrosis 20, S250, 2021 | | 2021 |
542: Toxicity profile of ELD607, a novel immunomodulator that reduces inflammation M Sassano, S Ahmad, J Wrennall, B Reidel, R Tarran Journal of Cystic Fibrosis 20, S256, 2021 | | 2021 |
551: ELD607 inhibits proinflammatory Ca2+ activity in cystic fibrosis patient neutrophils J Wrennall, S Ahmad, S Abdelwahab, A Ghosh, M Sassano, R Tarran Journal of Cystic Fibrosis 20, S260, 2021 | | 2021 |