| “A sweet combination”: developing saccharin and acesulfame K structures for selectively targeting the tumor-associated carbonic anhydrases IX and XII S Bua, C Lomelino, AB Murray, SM Osman, ZA ALOthman, M Bozdag, ... Journal of Medicinal Chemistry 63 (1), 321-333, 2019 | 29 | 2019 |
| 1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights T Al-Warhi, H Almahli, RM Maklad, ZM Elsayed, MA El Hassab, ... Molecules 28 (7), 3203, 2023 | 7 | 2023 |
| 1-Piperazinylphthalazines as potential VEGFR-2 inhibitors and anticancer agents: synthesis and in vitro biological evaluation SM Abou-Seri, WM Eldehna, MM Ali, DA Abou El Ella European journal of medicinal chemistry 107, 165-179, 2016 | 124 | 2016 |
| 1, 2, 4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking AE Elsawi, MI Shahin, HA Elbendary, T Al-Warhi, FE Hassan, ... Pharmaceuticals 17 (1), 81, 2024 | | 2024 |
| 1, 5-diaryl-1, 2, 4-triazole ureas as new SLC-0111 analogues endowed with dual carbonic anhydrase and VEGFR-2 inhibitory activities AE Elsawi, MM Elbadawi, A Nocentini, H Almahli, S Giovannuzzi, ... Journal of Medicinal Chemistry 66 (15), 10558-10578, 2023 | 9 | 2023 |
| 2-((Benzimidazol-2-yl) thio)-1-arylethan-1-ones: Synthesis, crystal study and cancer stem cells CD133 targeting potential HA Abdel-Aziz, HA Ghabbour, WM Eldehna, STA Al-Rashood, ... European Journal of Medicinal Chemistry 104, 1-10, 2015 | 24 | 2015 |
| 2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights MM Elbadawi, WM Eldehna, AA Abd El-Hafeez, WR Somaa, A Albohy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 355-378, 2022 | 20 | 2022 |
| 2, 4-Diaryl-pyrimido [1, 2-a] benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling MA Shaldam, D Hendrychová, R El-Haggar, V Vojáčková, TA Majrashi, ... European Journal of Medicinal Chemistry 258, 115610, 2023 | 4 | 2023 |
| 3-Acetyl-11-keto-β-boswellic Acid-Based Hybrids Alleviate Acetaminophen-Induced Hepatotoxicity in HepG2 by the Regulation of Inflammatory and Oxidative Stress Pathways: An … AA Elgazar, RA El-Domany, WM Eldehna, FA Badria ACS omega 8 (42), 39490-39510, 2023 | 3 | 2023 |
| 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico … MF Abo-Ashour, WM Eldehna, A Nocentini, A Bonardi, S Bua, HS Ibrahim, ... European Journal of Medicinal Chemistry 184, 111768, 2019 | 74 | 2019 |
| 3-Methylthiazolo [3, 2-a] benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and … AAM Alkhaldi, MM Al-Sanea, A Nocentini, WM Eldehna, ZM Elsayed, ... European Journal of Medicinal Chemistry 207, 112745, 2020 | 53 | 2020 |
| 4-(5-Amino-pyrazol-1-yl) benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic … MA Ragab, WM Eldehna, A Nocentini, A Bonardi, HE Okda, B Elgendy, ... European Journal of Medicinal Chemistry 250, 115180, 2023 | 19 | 2023 |
| A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico … FA Elshibani, AD Alamami, HA Mohammed, RA Rasheed, RM El Sabban, ... Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2293639, 2024 | 1 | 2024 |
| A patent review of anticancer CDK2 inhibitors (2017–present) MA Said, MA Abdelrahman, MAS Abourehab, M Fares, WM Eldehna Expert Opinion on Therapeutic Patents 32 (8), 885-898, 2022 | 8 | 2022 |
| Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII WM Eldehna, M Fares, M Ceruso, HA Ghabbour, SM Abou-Seri, ... European journal of medicinal chemistry 110, 259-266, 2016 | 82 | 2016 |
| An improved synthesis of pyrido [2, 3-d] pyrimidin-4 (1 H)-ones and their antimicrobial activity M Fares, SR Abd El Hadi, RA Eladwy, AA Shoun, MM Abdel-Aziz, ... Organic & Biomolecular Chemistry 16 (18), 3389-3395, 2018 | 20 | 2018 |
| An overview of recent advancements in small molecules suppression of oncogenic signaling of K-RAS: an updated review A Sabt, HO Tawfik, EF Khaleel, RM Badi, HAA Ibrahim, EB Elkaeed, ... Molecular Diversity, 1-28, 2024 | | 2024 |
| An updated review of fatty acid residue-tethered heterocyclic compounds: synthetic strategies and biological significance TA Majrashi, A Sabt, HA Abd El Salam, GH Al-Ansary, MF Hamissa, ... RSC advances 13 (20), 13655-13682, 2023 | 2 | 2023 |
| Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies RG Yousef, A Elwan, IMM Gobaara, ABM Mehany, WM Eldehna, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2206-2222, 2022 | 24 | 2022 |
| Anticoagulants as Potential SARS-CoV-2 Mpro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies A Abo Elmaaty, WM Eldehna, M Khattab, O Kutkat, R Alnajjar, ... International Journal of Molecular Sciences 23 (20), 12235, 2022 | 23 | 2022 |
Prof. Hatem A. Abdel-AzizDepartment of Applied Organic Chemistry, National Research Centre, Cairo, Egypt在 nrc.sci.eg 的电子邮件经过验证
