| 15: 00-17: 00 Monday, 21st June, 2021 Presentation type Poster MA Bond, A Testa, A Ciulli | | |
| 3-Fluoro-4-hydroxyprolines: synthesis, conformational analysis, and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation A Testa, X Lucas, GV Castro, KH Chan, JE Wright, AC Runcie, MS Gadd, ... Journal of the American Chemical Society 140 (29), 9299-9313, 2018 | 134 | 2018 |
| A beginner’s guide to PROTACs and targeted protein degradation A Ciulli, N Trainor The Biochemist 43 (5), 74-79, 2021 | 22 | 2021 |
| A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes MGJ Baud, E Lin-Shiao, T Cardote, C Tallant, A Pschibul, KH Chan, ... Science 346 (6209), 638-641, 2014 | 161 | 2014 |
| A Fragment‐Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry DE Scott, GJ Dawes, M Ando, C Abell, A Ciulli ChemBioChem 10 (17), 2772-2779, 2009 | 61 | 2009 |
| A new identity for BJ Structure C Lee, Y Jia, N Li, X Sun, K Ng, E Ambing, MY Gao, S Hua, C Chen, ... | | |
| A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo C Kofink, N Trainor, B Mair, S Wöhrle, M Wurm, N Mischerikow, MJ Roy, ... Nature Communications 13 (1), 5969, 2022 | 107 | 2022 |
| Abstract A179: The BRD4 degrader MZ1 exhibits potent antitumoral activity in diffuse large B cell lymphoma of the activated B cell-like type C Tarantelli, H Ekeh, C Moscatello, E Gaudio, A Testa, E Zucca, A Stathis, ... Molecular Cancer Therapeutics 17 (1_Supplement), A179-A179, 2018 | 6 | 2018 |
| Abstract IACICR01: Perspective on bivalent degraders A Ciulli Molecular Cancer Therapeutics 20 (12_Supplement), IACICR01-IACICR01, 2021 | | 2021 |
| Advanced chemical genetics for epigenetics: Bump-and-hole and PROTACs A Ciulli ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening FE Morreale, A Bortoluzzi, VK Chaugule, C Arkinson, H Walden, A Ciulli Journal of medicinal chemistry 60 (9), 4093-4098, 2017 | 35 | 2017 |
| Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity VG Klein, AG Bond, C Craigon, RS Lokey, A Ciulli Journal of medicinal chemistry 64 (24), 18082-18101, 2021 | 88 | 2021 |
| An HFSP fellowship that sowed the seeds for PROTAC drug development A Ciulli | | |
| and similarities to the hypoxia response.[version 1; referees: 2 J Frost, A Ciulli, S Rocha | | 2019 |
| Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase This research was supported by the … AW Hung, HL Silvestre, S Wen, A Ciulli, TL Blundell, C Abell Angewandte Chemie-German Edition 121 (45), 8604, 2009 | 186 | 2009 |
| Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121 SA Hudson, KJ McLean, S Surade, YQ Yang, D Leys, A Ciulli, AW Munro, ... Angewandte Chemie International Edition 51 (37), 9311-9316, 2012 | 97 | 2012 |
| Application of the interligand Overhauser effect to fragment linking and screening P Sledz, AW Hung, HL Silvestre, S Wen, A Ciulli, TL Blundell, C Abell ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | | 2010 |
| Automated determination of nuclear magnetic resonance chemical shift perturbations in ligand screening experiments: the PICASSO web server V Laveglia, A Giachetti, L Cerofolini, K Haubrich, M Fragai, A Ciulli, ... Journal of Chemical Information and Modeling 61 (12), 5726-5733, 2021 | 6 | 2021 |
| BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design W Farnaby, M Koegl, MJ Roy, C Whitworth, E Diers, N Trainor, D Zollman, ... Nature chemical biology 15 (7), 672-680, 2019 | 450 | 2019 |
| Bifunctional chemical probes inducing protein–protein interactions C Maniaci, A Ciulli Current Opinion in Chemical Biology 52, 145-156, 2019 | 98 | 2019 |
Andrea TestaAmphista Therapeutics在 amphista.com 的电子邮件经过验证
