Structure, function and pathophysiology of protease activated receptors MN Adams, R Ramachandran, MK Yau, JY Suen, DP Fairlie, ... Pharmacology & therapeutics, 2011 | 469 | 2011 |
Nucleophosmin: from structure and function to disease development JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ... BMC molecular biology 17, 1-12, 2016 | 270 | 2016 |
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ... Frontiers in oncology 4, 86, 2014 | 139 | 2014 |
Proteolysis-induced n-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of … Y He, A Wortmann, LJ Burke, JC Reid, MN Adams, I Abdul-Jabbar, ... Journal of Biological Chemistry 285 (34), 26162-26173, 2010 | 83 | 2010 |
Expression of CDCA3 is a prognostic biomarker and potential therapeutic target in non–small cell lung cancer MN Adams, JT Burgess, Y He, K Gately, C Snell, SD Zhang, JD Hooper, ... Journal of Thoracic Oncology 12 (7), 1071-1084, 2017 | 77 | 2017 |
Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance Y He, AC Wu, BS Harrington, CM Davies, SJ Wallace, MN Adams, ... Oncogene 35 (4), 468-478, 2016 | 58 | 2016 |
The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2 MN Adams, ME Christensen, Y He, NJ Waterhouse, JD Hooper PLoS One 6 (11), e28018, 2011 | 58 | 2011 |
Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer BS Harrington, Y He, CM Davies, SJ Wallace, MN Adams, EA Beaven, ... British journal of cancer 114 (4), 417-426, 2016 | 57 | 2016 |
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) AJ Ramsay, JC Reid, MN Adams, H Samaratunga, Y Dong, JA Clements, ... Biological chemistry 389 (6), 653-668, 2008 | 53 | 2008 |
Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) C O’Leary, H Gasper, KB Sahin, M Tang, A Kulasinghe, MN Adams, ... Pharmaceuticals 13 (10), 273, 2020 | 52 | 2020 |
hSSB1 (NABP2/OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway N Paquet, MN Adams, V Leong, NW Ashton, C Touma, R Gamsjaeger, ... Nucleic acids research 43 (18), 8817-8829, 2015 | 48 | 2015 |
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage E Bolderson, JT Burgess, J Li, NS Gandhi, D Boucher, LV Croft, S Beard, ... Nature communications 10 (1), 5501, 2019 | 47 | 2019 |
SARS-CoV-2 DNA vaccine INO-4800 induces durable immune responses capable of being boosted in a phase 1 open-label trial KA Kraynyak, E Blackwood, J Agnes, P Tebas, M Giffear, D Amante, ... The Journal of infectious diseases 225 (11), 1923-1932, 2022 | 41 | 2022 |
hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress N Paquet, MN Adams, NW Ashton, C Touma, R Gamsjaeger, L Cubeddu, ... Scientific reports 6 (1), 27446, 2016 | 39 | 2016 |
EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface MN Adams, BS Harrington, Y He, CM Davies, SJ Wallace, NP Chetty, ... Oncogene 34 (11), 1375-1383, 2015 | 39 | 2015 |
Human single-stranded DNA binding protein 1 (hSSB1, OBFC2B), a critical component of the DNA damage response LV Croft, E Bolderson, MN Adams, S El-Kamand, R Kariawasam, ... Seminars in cell & developmental biology 86, 121-128, 2019 | 36 | 2019 |
CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin Y He, CM Davies, BS Harrington, L Hellmers, Y Sheng, A Broomfield, ... Oncogene 39 (1), 219-233, 2020 | 31 | 2020 |
Targeting NF-κB-mediated inflammatory pathways in cisplatin-resistant NSCLC SL Ryan, S Beard, MP Barr, K Umezawa, S Heavey, P Godwin, SG Gray, ... Lung Cancer 135, 217-227, 2019 | 29 | 2019 |
Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response JT Burgess, E Bolderson, MN Adams, AM Baird, SD Zhang, KA Gately, ... Cell death & disease 7 (11), e2469-e2469, 2016 | 29 | 2016 |
A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution C Touma, R Kariawasam, AX Gimenez, RE Bernardo, NW Ashton, ... Nucleic acids research 44 (16), 7963-7973, 2016 | 29 | 2016 |