| Pulmonary macrophage transplantation therapy T Suzuki, P Arumugam, T Sakagami, N Lachmann, C Chalk, A Sallese, ... Nature 514 (7523), 450-454, 2014 | 319 | 2014 |
| Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies N Lachmann, M Ackermann, E Frenzel, S Liebhaber, S Brennig, C Happle, ... Stem cell reports 4 (2), 282-296, 2015 | 231 | 2015 |
| Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections M Ackermann, H Kempf, M Hetzel, C Hesse, AR Hashtchin, K Brinkert, ... Nature communications 9 (1), 1-13, 2018 | 132 | 2018 |
| Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis C Happle, N Lachmann, J Škuljec, M Wetzke, M Ackermann, S Brennig, ... Science translational medicine 6 (250), 250ra113-250ra113, 2014 | 129 | 2014 |
| Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis N Lachmann, C Happle, M Ackermann, D Lüttge, M Wetzke, S Merkert, ... American journal of respiratory and critical care medicine 189 (2), 167-182, 2014 | 112 | 2014 |
| Generation of HLA-universal iPSC-derived megakaryocytes and platelets for survival under refractoriness conditions AK Börger, D Eicke, C Wolf, C Gras, S Aufderbeck, K Schulze, L Engels, ... Molecular medicine 22 (1), 274-285, 2016 | 103 | 2016 |
| Lost in translation: pluripotent stem cell‐derived hematopoiesis M Ackermann, S Liebhaber, JH Klusmann, N Lachmann EMBO molecular medicine 7 (11), 1388-1402, 2015 | 101 | 2015 |
| A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and … U Müller-Kuller, M Ackermann, S Kolodziej, C Brendel, J Fritsch, ... Nucleic acids research 43 (3), 1577-1592, 2015 | 91 | 2015 |
| TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells AK Dreyer, D Hoffmann, N Lachmann, M Ackermann, D Steinemann, ... Biomaterials 69, 191-200, 2015 | 90 | 2015 |
| A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny N Pfaff, N Lachmann, M Ackermann, S Kohlscheen, C Brendel, T Maetzig, ... Stem Cells 31 (3), 488-499, 2013 | 90 | 2013 |
| Pulmonary transplantation of human induced pluripotent stem cell–derived macrophages ameliorates pulmonary alveolar proteinosis C Happle, N Lachmann, M Ackermann, A Mirenska, G Göhring, K Thomay, ... American journal of respiratory and critical care medicine 198 (3), 350-360, 2018 | 73 | 2018 |
| Lung surfactant metabolism: early in life, early in disease and target in cell therapy E Lopez-Rodriguez, G Gay-Jordi, A Mucci, N Lachmann, ... Cell and tissue research 367 (3), 721-735, 2017 | 67 | 2017 |
| Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy M Ackermann, N Lachmann, S Hartung, R Eggenschwiler, N Pfaff, ... Biomaterials 35 (5), 1531-1542, 2014 | 57 | 2014 |
| MicroRNA-based therapy of GATA2-deficient vascular disease D Hartmann, J Fiedler, K Sonnenschein, A Just, A Pfanne, K Zimmer, ... Circulation 134 (24), 1973-1990, 2016 | 56 | 2016 |
| iPSC-derived macrophages effectively treat pulmonary alveolar proteinosis in Csf2rb-deficient mice A Mucci, E Lopez-Rodriguez, M Hetzel, S Liu, T Suzuki, C Happle, ... Stem cell reports 11 (3), 696-710, 2018 | 53 | 2018 |
| Enhanced ex vivo generation of erythroid cells from human induced pluripotent stem cells in a simplified cell culture system with low cytokine support C Bernecker, M Ackermann, N Lachmann, L Rohrhofer, H Zaehres, ... Stem cells and development 28 (23), 1540-1551, 2019 | 52 | 2019 |
| Gene therapy of cancer: translational approaches from preclinical studies to clinical implementation SL Gerson, EC Lattime Elsevier, 2002 | 51 | 2002 |
| Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell‐Derived Blood Cells—Ready for Take‐Off K Haake, M Ackermann, N Lachmann Stem cells translational medicine 8 (4), 332-339, 2019 | 40 | 2019 |
| Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells N Pfaff, N Lachmann, S Kohlscheen, M Sgodda, MJ Araúzo-Bravo, ... Stem cells and development 21 (5), 689-701, 2012 | 36 | 2012 |
| Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages AL Neehus, J Lam, K Haake, S Merkert, N Schmidt, A Mucci, ... Stem cell reports 10 (1), 7-16, 2018 | 34 | 2018 |
