β‐Peptides: Synthesis by Arndt‐Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray … D Seebach, M Overhand, FNM Kühnle, B Martinoni, L Oberer, U Hommel, ... Helvetica Chimica Acta 79 (4), 913-941, 1996 | 1089 | 1996 |
Probing the helical secondary structure of short‐chain β‐peptides D Seebach, PE Ciceri, M Overhand, B Jaun, D Rigo, L Oberer, U Hommel, ... Helvetica chimica acta 79 (8), 2043-2066, 1996 | 513 | 1996 |
β2‐ and β3‐Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the … D Seebach, S Abele, K Gademann, G Guichard, T Hintermann, B Jaun, ... Helvetica Chimica Acta 81 (5‐8), 932-982, 1998 | 505 | 1998 |
Origin of t 1 and t 2 ridges in 2D NMR spectra and procedures for suppression G Otting, H Widmer, G Wagner, K Wüthrich NMR Struct. Biol, 389-395, 1995 | 375 | 1995 |
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy J Kallen, C Spitzfaden, MGM Zurini, G Wider, H Widmer, K Wüthrich, ... Nature 353 (6341), 276-279, 1991 | 345 | 1991 |
NMR structure of cyclosporin A bound to cyclophilin in aqueous solution C Weber, G Wider, B Von Freyberg, R Traber, W Braun, H Widmer, ... Biochemistry 30 (26), 6563-6574, 1991 | 326 | 1991 |
‘Mixed’β‐peptides: A unique helical secondary structure in solution. Preliminary communication D Seebach, K Gademann, JRV Schreiber, JL Matthews, T Hintermann, ... Helvetica chimica acta 80 (7), 2033-2038, 1997 | 303 | 1997 |
Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides K Johnsson, RK Allemann, H Widmer, SA Benner Nature 365 (6446), 530-532, 1993 | 285 | 1993 |
Structural and biophysical characterization of the EphB4· EphrinB2 protein-protein interaction and receptor specificity JE Chrencik, A Brooun, ML Kraus, MI Recht, AR Kolatkar, GW Han, ... Journal of Biological Chemistry 281 (38), 28185-28192, 2006 | 122 | 2006 |
Simulated two-dimensional NMR cross-peak fine structures for 1H spin systems in polypeptides and polydeoxynucleotides H Widmer, K Wüthrich Journal of Magnetic Resonance (1969) 74 (2), 316-336, 1987 | 116 | 1987 |
Protein NMR in biomedical research W Jahnke, H Widmer Cellular and Molecular Life Sciences CMLS 61, 580-599, 2004 | 115 | 2004 |
Receptor-induced conformation change of the immunosuppressant cyclosporin A K Wüthrich, B Von Freyberg, C Weber, G Wider, R Traber, H Widmer, ... Science 254 (5034), 953-954, 1991 | 114 | 1991 |
Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data C Spitzfaden, HP Weber, W Braun, J Kallen, G Wider, H Widmer, ... FEBS letters 300 (3), 291-300, 1992 | 112 | 1992 |
Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity JE Chrencik, A Brooun, MI Recht, ML Kraus, M Koolpe, AR Kolatkar, ... Structure 14 (2), 321-330, 2006 | 111 | 2006 |
Conformational studies of d (AAAAATTTTT) 2 using constraints from nuclear Overhauser effects and from quantitative analysis of the cross-peak fine structures in two-dimensional … B Celda, H Widmer, W Leupin, WJ Chazin, WA Denny, K Wuethrich Biochemistry 28 (4), 1462-1471, 1989 | 101 | 1989 |
Three‐dimensional structure of the neurotoxin ATX Ia from Anemonia sulcata in aqueous solution determined by nuclear magnetic resonance spectroscopy H Widmer, M Billeter, K Wüthrich Proteins: Structure, Function, and Bioinformatics 6 (4), 357-371, 1989 | 98 | 1989 |
The 3D structure of a cyclosporin analogue in water is nearly identical to the cyclophilin-bound cyclosporin conformation RM Wenger, J France, G Bovermann, L Walliser, A Widmer, H Widmer FEBS letters 340 (3), 255-259, 1994 | 89 | 1994 |
Use of a double half-filter in two-dimensional proton NMR studies of receptor-bound cyclosporin G Wider, C Weber, R Traber, H Widmer, K Wuethrich Journal of the American Chemical Society 112 (24), 9015-9016, 1990 | 83 | 1990 |
Simulation of two-dimensional NMR experiments using numerical density matrix calculations H Widmer, K Wüthrich Journal of Magnetic Resonance (1969) 70 (2), 270-279, 1986 | 83 | 1986 |
Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex C Spitzfaden, W Braun, G Wider, H Widmer, K Wüthrich Journal of biomolecular NMR 4, 463-482, 1994 | 80 | 1994 |