Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells MS Kim, MJ Haney, Y Zhao, V Mahajan, I Deygen, NL Klyachko, E Inskoe, ... Nanomedicine: Nanotechnology, Biology and Medicine 12 (3), 655-664, 2016 | 1266 | 2016 |
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy LS Sasportas, R Kasmieh, H Wakimoto, S Hingtgen, JAJM van de Water, ... Proceedings of the national academy of sciences 106 (12), 4822-4827, 2009 | 580 | 2009 |
Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas TM Kauer, JL Figueiredo, S Hingtgen, K Shah Nature neuroscience 15 (2), 197-204, 2012 | 239 | 2012 |
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy SD Hingtgen, X Tian, J Yang, SM Dunlay, AS Peek, Y Wu, RV Sharma, ... Physiological genomics 26 (3), 180-191, 2006 | 191 | 2006 |
Specific transfection of inflamed brain by macrophages: a new therapeutic strategy for neurodegenerative diseases MJ Haney, Y Zhao, EB Harrison, V Mahajan, S Ahmed, Z He, P Suresh, ... PloS one 8 (4), e61852, 2013 | 162 | 2013 |
Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy M Duebgen, J Martinez-Quintanilla, K Tamura, S Hingtgen, N Redjal, ... Journal of the national cancer institute 106 (6), dju090, 2014 | 132 | 2014 |
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model K Shah, S Hingtgen, R Kasmieh, JL Figueiredo, E Garcia-Garcia, ... Journal of Neuroscience 28 (17), 4406-4413, 2008 | 127 | 2008 |
Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma JR Bagó, A Alfonso-Pecchio, O Okolie, R Dumitru, A Rinkenbaugh, ... Nature communications 7 (1), 10593, 2016 | 126 | 2016 |
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model O Okolie, JR Bago, RS Schmid, DM Irvin, RE Bash, CR Miller, ... Neuro-oncology 18 (12), 1622-1633, 2016 | 120 | 2016 |
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide S Hingtgen, X Ren, E Terwilliger, M Classon, R Weissleder, K Shah Molecular cancer therapeutics 7 (11), 3575-3585, 2008 | 104 | 2008 |
Tumor-homing cytotoxic human induced neural stem cells for cancer therapy JR Bagó, O Okolie, R Dumitru, MG Ewend, JS Parker, RV Werff, ... Science translational medicine 9 (375), eaah6510, 2017 | 96 | 2017 |
Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins NL Klyachko, MJ Haney, Y Zhao, DS Manickam, V Mahajan, P Suresh, ... Nanomedicine 9 (9), 1403-1422, 2014 | 95 | 2014 |
Engineered mesenchymal stem cell/nanomedicine spheroid as an active drug delivery platform for combinational glioblastoma therapy S Suryaprakash, YH Lao, HY Cho, M Li, HY Ji, D Shao, H Hu, CH Quek, ... Nano Letters 19 (3), 1701-1705, 2019 | 84 | 2019 |
Electrospun nanofibrous scaffolds increase the efficacy of stem cell-mediated therapy of surgically resected glioblastoma JR Bagó, GJ Pegna, O Okolie, M Mohiti-Asli, EG Loboa, SD Hingtgen Biomaterials 90, 116-125, 2016 | 74 | 2016 |
Neural stem cell therapy for cancer JR Bagó, KT Sheets, SD Hingtgen Methods 99, 37-43, 2016 | 67 | 2016 |
Real-time multi-modality imaging of glioblastoma tumor resection and recurrence S Hingtgen, JL Figueiredo, C Farrar, M Duebgen, J Martinez-Quintanilla, ... Journal of neuro-oncology 111, 153-161, 2013 | 66 | 2013 |
A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy SD Hingtgen, R Kasmieh, J van de Water, R Weissleder, K Shah Stem Cells 28 (4), 832-841, 2010 | 65 | 2010 |
Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo E Arwert, S Hingtgen, JL Figueiredo, H Bergquist, U Mahmood, ... Cancer research 67 (15), 7335-7342, 2007 | 58 | 2007 |
Sustained delivery of doxorubicin via acetalated dextran scaffold prevents glioblastoma recurrence after surgical resection E Graham-Gurysh, KM Moore, AB Satterlee, KT Sheets, FC Lin, ... Molecular pharmaceutics 15 (3), 1309-1318, 2018 | 47 | 2018 |
Engineering toxin-resistant therapeutic stem cells to treat brain tumors DW Stuckey, SD Hingtgen, N Karakas, BE Rich, K Shah Stem cells 33 (2), 589-600, 2015 | 46 | 2015 |