Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling WB Cárdenas, YM Loo, M Gale Jr, AL Hartman, CR Kimberlin, ... Journal of virology 80 (11), 5168-5178, 2006 | 564 | 2006 |
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression KM Hastie, CR Kimberlin, MA Zandonatti, IJ MacRae, EO Saphire Proceedings of the National Academy of Sciences 108 (6), 2396-2401, 2011 | 306 | 2011 |
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression CR Kimberlin, ZA Bornholdt, S Li, VL Woods Jr, IJ MacRae, EO Saphire Proceedings of the National Academy of Sciences 107 (1), 314-319, 2010 | 161 | 2010 |
Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab SM Chin, CR Kimberlin, Z Roe-Zurz, P Zhang, A Xu, S Liao-Chan, D Sen, ... Nature communications 9 (1), 4679, 2018 | 128 | 2018 |
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism S Bale, JP Julien, ZA Bornholdt, CR Kimberlin, P Halfmann, ... Public Library of Science 8 (9), e1002916, 2012 | 89 | 2012 |
A glutamate switch controls voltage-sensitive phosphatase function L Liu, SC Kohout, Q Xu, S Müller, CR Kimberlin, EY Isacoff, DL Minor Jr Nature structural & molecular biology 19 (6), 633-641, 2012 | 56 | 2012 |
Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses KM Hastie, S Bale, CR Kimberlin, EO Saphire Current opinion in virology 2 (2), 151-156, 2012 | 46 | 2012 |
Direct control of CAR T cells through small molecule-regulated antibodies S Park, E Pascua, KC Lindquist, C Kimberlin, X Deng, YSL Mak, Z Melton, ... Nature Communications 12 (1), 710, 2021 | 34 | 2021 |
Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions F Wang, B Chau, SM West, CR Kimberlin, F Cao, F Schwarz, B Aguilar, ... Nature Communications 12 (1), 1378, 2021 | 15 | 2021 |
SARAF luminal domain structure reveals a novel domain-swapped β-sandwich fold important for SOCE modulation CR Kimberlin, A Meshcheriakova, R Palty, A Raveh, I Karbat, E Reuveny, ... Journal of molecular biology 431 (15), 2869-2883, 2019 | 14 | 2019 |
Pharmacologic properties and preclinical activity of sasanlimab, a high-affinity engineered anti-human PD-1 antibody AA Al-Khami, S Youssef, Y Abdiche, HK Nguyen, J Chou, CR Kimberlin, ... Molecular Cancer Therapeutics 19 (10), 2105-2116, 2020 | 9 | 2020 |
L. 18 Martinez-Sobrido, EO Saphire, and CF Basler. 2006. Ebola virus VP35 protein 19 binds double-stranded RNA and inhibits alpha/beta interferon production induced by 20 RIG-I … WB Cardenas, YM Loo, M Gale Jr, AL Hartman, CR Kimberlin J Virol 80, 5168-78, 0 | 5 | |
Selective activation of the IL-2 pathway in CD8+ T cells drives antiviral activity in a hepatitis B virus (HBV) model KD Moynihan, F Andreata, P Di Lucia, D Pappas, I Ni, P Bessette, ... The Liver Meeting. Washington DC Hepatology 76, 2022 | 2 | 2022 |
0., and Basler, CF 2006. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling WB Cardenas, YM Loo, M Gale, AL Hartman, CR Kimberlin, ... J. Wrol 80, 5168-5178, 0 | 2 | |
CAR-targeted IL-2 drives selective CAR-T cell expansion and improves anti-tumor efficacy ND Mathewson, KD Moynihan, S Sleiman, W Chen, P Bessette, ... Cancer Research 82 (12), 2022 | 1 | 2022 |
Targeted cytokine construct for engineered cell therapy I Djuretic, K Moynihan, W Chen, P Bessette, C Kimberlin, N Mathewson, ... US Patent App. 18/256,512, 2024 | | 2024 |
The Molecular Basis for SOCE Regulation by SARAF A Meshcheriakova, C Kimberlin, R Palty, I Karbat, DL Minor, E Reuveny Biophysical Journal 118 (3), 568a, 2020 | | 2020 |
A glutamate switch controls voltage-sensitive phosphatase function D Minor, L Liu, SC Kohout, Q Xu, S Müller, CR Kimberlin, EY Isacoff, ... | | 2012 |
Structure and RNA Binding Mechanism of Ebolavirus VP35: A Thesis Presented CR Kimberlin Scripps Research Institute, La Jolla, California, 2010 | | 2010 |
Structure and RNA binding mechanism of ebolavirus VP35 CR Kimberlin The Scripps Research Institute, 2010 | | 2010 |