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Christopher Kimberlin
Christopher Kimberlin
Asher Biotherapeutics
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引用次数
引用次数
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Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling
WB Cárdenas, YM Loo, M Gale Jr, AL Hartman, CR Kimberlin, ...
Journal of virology 80 (11), 5168-5178, 2006
5642006
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression
KM Hastie, CR Kimberlin, MA Zandonatti, IJ MacRae, EO Saphire
Proceedings of the National Academy of Sciences 108 (6), 2396-2401, 2011
3062011
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression
CR Kimberlin, ZA Bornholdt, S Li, VL Woods Jr, IJ MacRae, EO Saphire
Proceedings of the National Academy of Sciences 107 (1), 314-319, 2010
1612010
Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
SM Chin, CR Kimberlin, Z Roe-Zurz, P Zhang, A Xu, S Liao-Chan, D Sen, ...
Nature communications 9 (1), 4679, 2018
1282018
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism
S Bale, JP Julien, ZA Bornholdt, CR Kimberlin, P Halfmann, ...
Public Library of Science 8 (9), e1002916, 2012
892012
A glutamate switch controls voltage-sensitive phosphatase function
L Liu, SC Kohout, Q Xu, S Müller, CR Kimberlin, EY Isacoff, DL Minor Jr
Nature structural & molecular biology 19 (6), 633-641, 2012
562012
Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses
KM Hastie, S Bale, CR Kimberlin, EO Saphire
Current opinion in virology 2 (2), 151-156, 2012
462012
Direct control of CAR T cells through small molecule-regulated antibodies
S Park, E Pascua, KC Lindquist, C Kimberlin, X Deng, YSL Mak, Z Melton, ...
Nature Communications 12 (1), 710, 2021
342021
Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions
F Wang, B Chau, SM West, CR Kimberlin, F Cao, F Schwarz, B Aguilar, ...
Nature Communications 12 (1), 1378, 2021
152021
SARAF luminal domain structure reveals a novel domain-swapped β-sandwich fold important for SOCE modulation
CR Kimberlin, A Meshcheriakova, R Palty, A Raveh, I Karbat, E Reuveny, ...
Journal of molecular biology 431 (15), 2869-2883, 2019
142019
Pharmacologic properties and preclinical activity of sasanlimab, a high-affinity engineered anti-human PD-1 antibody
AA Al-Khami, S Youssef, Y Abdiche, HK Nguyen, J Chou, CR Kimberlin, ...
Molecular Cancer Therapeutics 19 (10), 2105-2116, 2020
92020
L. 18 Martinez-Sobrido, EO Saphire, and CF Basler. 2006. Ebola virus VP35 protein 19 binds double-stranded RNA and inhibits alpha/beta interferon production induced by 20 RIG-I …
WB Cardenas, YM Loo, M Gale Jr, AL Hartman, CR Kimberlin
J Virol 80, 5168-78, 0
5
Selective activation of the IL-2 pathway in CD8+ T cells drives antiviral activity in a hepatitis B virus (HBV) model
KD Moynihan, F Andreata, P Di Lucia, D Pappas, I Ni, P Bessette, ...
The Liver Meeting. Washington DC Hepatology 76, 2022
22022
0., and Basler, CF 2006. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling
WB Cardenas, YM Loo, M Gale, AL Hartman, CR Kimberlin, ...
J. Wrol 80, 5168-5178, 0
2
CAR-targeted IL-2 drives selective CAR-T cell expansion and improves anti-tumor efficacy
ND Mathewson, KD Moynihan, S Sleiman, W Chen, P Bessette, ...
Cancer Research 82 (12), 2022
12022
Targeted cytokine construct for engineered cell therapy
I Djuretic, K Moynihan, W Chen, P Bessette, C Kimberlin, N Mathewson, ...
US Patent App. 18/256,512, 2024
2024
The Molecular Basis for SOCE Regulation by SARAF
A Meshcheriakova, C Kimberlin, R Palty, I Karbat, DL Minor, E Reuveny
Biophysical Journal 118 (3), 568a, 2020
2020
A glutamate switch controls voltage-sensitive phosphatase function
D Minor, L Liu, SC Kohout, Q Xu, S Müller, CR Kimberlin, EY Isacoff, ...
2012
Structure and RNA Binding Mechanism of Ebolavirus VP35: A Thesis Presented
CR Kimberlin
Scripps Research Institute, La Jolla, California, 2010
2010
Structure and RNA binding mechanism of ebolavirus VP35
CR Kimberlin
The Scripps Research Institute, 2010
2010
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