Rac–MEKK3–MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock MT Uhlik, AN Abell, NL Johnson, W Sun, BD Cuevas, KE Lobel-Rice, ... Nature cell biology 5 (12), 1104-1110, 2003 | 458 | 2003 |
The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells Y Lu, YZ Lin, R LaPushin, B Cuevas, X Fang, SX Yu, MA Davies, H Khan, ... Oncogene 18 (50), 7034-7045, 1999 | 444 | 1999 |
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas Y Yu, F Xu, H Peng, X Fang, S Zhao, Y Li, B Cuevas, WL Kuo, JW Gray, ... Proceedings of the National Academy of Sciences 96 (1), 214-219, 1999 | 413 | 1999 |
Role of mitogen-activated protein kinase kinase kinases in signal integration BD Cuevas, AN Abell, GL Johnson Oncogene 26 (22), 3159-3171, 2007 | 375 | 2007 |
Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase BD Cuevas, Y Lu, M Mao, J Zhang, R LaPushin, K Siminovitch, GB Mills Journal of Biological Chemistry 276 (29), 27455-27461, 2001 | 337 | 2001 |
SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity B Cuevas, Y Lu, S Watt, R Kumar, J Zhang, KA Siminovitch, GB Mills Journal of Biological Chemistry 274 (39), 27583-27589, 1999 | 210 | 1999 |
MEKK1 regulates calpain‐dependent proteolysis of focal adhesion proteins for rear‐end detachment of migrating fibroblasts BD Cuevas, AN Abell, JA Witowsky, T Yujiri, NL Johnson, K Kesavan, ... The EMBO journal, 2003 | 180 | 2003 |
Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion P Arora, BD Cuevas, A Russo, GL Johnson, J Trejo Oncogene 27 (32), 4434-4445, 2008 | 152 | 2008 |
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors A Beltran, S Parikh, Y Liu, BD Cuevas, GL Johnson, BW Futscher, ... Oncogene 26 (19), 2791-2798, 2007 | 115 | 2007 |
Wiring diagrams of MAPK regulation by MEKK1, 2, and 3 MT Uhlik, AN Abell, BD Cuevas, K Nakamura, GL Johnson Biochemistry and cell biology 82 (6), 658-663, 2004 | 115 | 2004 |
Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis MR Cronan, K Nakamura, NL Johnson, DA Granger, BD Cuevas, ... Oncogene 31 (34), 3889-3900, 2012 | 89 | 2012 |
Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo AN Abell, JA Rivera-Perez, BD Cuevas, MT Uhlik, S Sather, NL Johnson, ... Molecular and cellular biology, 2005 | 88 | 2005 |
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer BD Cuevas, AM Winter-Vann, NL Johnson, GL Johnson Oncogene 25 (36), 4998-5010, 2006 | 75 | 2006 |
Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype NY Li, CE Weber, Z Mi, PY Wai, BD Cuevas, PC Kuo Journal of the American College of Surgeons 217 (1), 17-26, 2013 | 56 | 2013 |
Phosphatidylinositol 3-kinase is required for CD28 but not CD3 regulation of the TEC family tyrosine kinase EMT/ITK/TSK: functional and physical interaction of EMT with … Y Lu, B Cuevas, S Gibson, H Khan, R LaPushin, J Imboden, GB Mills The Journal of Immunology 161 (10), 5404-5412, 1998 | 55 | 1998 |
MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability BD Cuevas, MT Uhlik, TP Garrington, GL Johnson Oncogene 24 (5), 801-809, 2005 | 48 | 2005 |
An MAPK-dependent pathway induces epithelial-mesenchymal transition via Twist activation in human breast cancer cell lines NY Li, CE Weber, PY Wai, BD Cuevas, J Zhang, PC Kuo, Z Mi Surgery 154 (2), 404-410, 2013 | 44 | 2013 |
MEKK1 is required for inducible urokinase-type plasminogen activator expression J Witowsky, A Abell, NL Johnson, GL Johnson, BD Cuevas Journal of Biological Chemistry 278 (8), 5941-5946, 2003 | 37 | 2003 |
Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells M Perez-Neut, A Shum, BD Cuevas, R Miller, S Gentile Oncotarget 6 (3), 1631, 2015 | 34 | 2015 |
MEKK2 regulates focal adhesion stability and motility in invasive breast cancer cells AA Mirza, MP Kahle, M Ameka, EM Campbell, BD Cuevas Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (5), 945-954, 2014 | 25 | 2014 |