High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... Science translational medicine 9 (377), eaaf2584, 2017 | 359 | 2017 |
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... Cell reports 32 (3), 107925, 2020 | 258 | 2020 |
Use of human induced pluripotent stem cell–derived cardiomyocytes to assess drug cardiotoxicity A Sharma, WL McKeithan, R Serrano, T Kitani, PW Burridge, ... Nature protocols 13 (12), 3018-3041, 2018 | 140 | 2018 |
High throughput physiological screening of iPSC-derived cardiomyocytes for drug development JC del Álamo, D Lemons, R Serrano, A Savchenko, F Cerignoli, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1717-1727, 2016 | 133 | 2016 |
Rickettsia Sca4 reduces vinculin-mediated intercellular tension to promote spread RL Lamason, E Bastounis, NM Kafai, R Serrano, JC Del Álamo, ... Cell 167 (3), 670-683. e10, 2016 | 104 | 2016 |
Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis YT Yeh, R Serrano, J François, JJ Chiu, YSJ Li, JC Del Álamo, S Chien, ... Proceedings of the National Academy of Sciences 115 (1), 133-138, 2018 | 66 | 2018 |
Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling I Banerjee, K Carrion, R Serrano, J Dyo, R Sasik, S Lund, E Willems, ... Journal of molecular and cellular cardiology 79, 133-144, 2015 | 66 | 2015 |
Reengineering an antiarrhythmic drug using patient hiPSC cardiomyocytes to improve therapeutic potential and reduce toxicity WL McKeithan, DAM Feyen, AAN Bruyneel, KJ Okolotowicz, DA Ryan, ... Cell Stem Cell 27 (5), 813-821. e6, 2020 | 43 | 2020 |
MiR-145 mediates cell morphology-regulated mesenchymal stem cell differentiation to smooth muscle cells YT Yeh, J Wei, S Thorossian, K Nguyen, C Hoffman, JC del Álamo, ... Biomaterials 204, 59-69, 2019 | 39 | 2019 |
Three-dimensional monolayer stress microscopy R Serrano, A Aung, YT Yeh, S Varghese, JC Lasheras, JC del Álamo Biophysical journal 117 (1), 111-128, 2019 | 37 | 2019 |
Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming M Gálvez-Santisteban, D Chen, R Zhang, R Serrano, C Nguyen, L Zhao, ... eLife 8, e44816, 2019 | 33 | 2019 |
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy I Perea-Gil, T Seeger, AAN Bruyneel, V Termglinchan, E Monte, EW Lim, ... European Heart Journal 43 (36), 3477-3489, 2022 | 31 | 2022 |
miR-486 is modulated by stretch and increases ventricular growth S Lange, I Banerjee, K Carrion, R Serrano, L Habich, R Kameny, ... JCI insight, 2019 | 27 | 2019 |
A novel recessive mutation in SPEG causes early onset dilated cardiomyopathy A Levitas, E Muhammad, Y Zhang, I Perea Gil, R Serrano, N Diaz, ... PLoS genetics 16 (9), e1009000, 2020 | 26 | 2020 |
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Sci Transl Med 9 A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... Epub 2017/02/17. 10.1126/scitranslmed. aaf2584, 2017 | 20 | 2017 |
Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes. Cell Rep 32: 107925 DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... | 13 | 2020 |
A deep learning platform to assess drug proarrhythmia risk R Serrano, DAM Feyen, AAN Bruyneel, AP Hnatiuk, MM Vu, PL Amatya, ... Cell Stem Cell, 2022 | 12 | 2022 |
Early committed polarization of intracellular tension in response to cell shape determines the osteogenic differentiation of mesenchymal stromal cells MC Wu, HW Yu, YQ Chen, MH Ou, R Serrano, GL Huang, YK Wang, K Lin, ... Acta Biomaterialia, 2022 | 8 | 2022 |
A Multi-well Format Polyacrylamide-based Assay for Studying the Effect of Extracellular Matrix Stiffness on the Bacterial Infection of Adherent Cells EE Bastounis, FE Ortega, R Serrano, JA Theriot JoVE (Journal of Visualized Experiments), e57361, 2018 | 8 | 2018 |
Reengineering Ponatinib to Minimize Cardiovascular Toxicity. AP Hnatiuk, AAN Bruyneel, D Tailor, M Pandrala, A Dheeraj, W Li, ... Cancer Research, canres. CAN-21, 2022 | 7 | 2022 |