Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension L Bodineau, A Frugiere, Y Marc, N Inguimbert, C Fassot, F Balavoine, ... Hypertension 51 (5), 1318-1325, 2008 | 109 | 2008 |
On-resin cyclization of peptide ligands of the vascular endothelial growth factor receptor 1 by copper (I)-catalyzed 1, 3-dipolar azide–alkyne cycloaddition V Goncalves, B Gautier, A Regazzetti, P Coric, S Bouaziz, C Garbay, ... Bioorganic & medicinal chemistry letters 17 (20), 5590-5594, 2007 | 61 | 2007 |
Development of a chemiluminescent screening assay for detection of vascular endothelial growth factor receptor 1 ligands. V Goncalves, B Gautier, C Garbay, M Vidal, N Inguimbert Analytical biochemistry 366 (1), 108-10, 2007 | 51 | 2007 |
Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening B Gautier, MA Miteva, V Goncalves, F Huguenot, P Coric, S Bouaziz, ... Chemistry & biology 18 (12), 1631-1639, 2011 | 50 | 2011 |
Immunosensors for estradiol and ethinylestradiol based on new synthetic estrogen derivatives: application to wastewater analysis H Kanso, L Barthelmebs, N Inguimbert, T Noguer Analytical Chemistry 85 (4), 2397-2404, 2013 | 47 | 2013 |
Biochemical and structural analysis of the binding determinants of a vascular endothelial growth factor receptor peptidic antagonist B Gautier, V Goncalves, D Diana, R Di Stasi, F Teillet, C Lenoir, ... Journal of medicinal chemistry 53 (11), 4428-4440, 2010 | 45 | 2010 |
Outstanding marine molecules: chemistry, biology, analysis S La Barre, JM Kornprobst John Wiley & Sons, 2014 | 44 | 2014 |
Rational design, structure, and biological evaluation of cyclic peptides mimicking the vascular endothelial growth factor V Goncalves, B Gautier, P Coric, S Bouaziz, C Lenoir, C Garbay, M Vidal, ... Journal of medicinal chemistry 50 (21), 5135-5146, 2007 | 43 | 2007 |
N-[2-(Indan-1-yl)-3-mercapto-propionyl] amino acids as highly potent inhibitors of the three vasopeptidases (NEP, ACE, ECE): in vitro and in vivo activities N Inguimbert, H Poras, F Teffo, F Beslot, M Selkti, A Tomas, E Scalbert, ... Bioorganic & medicinal chemistry letters 12 (15), 2001-2005, 2002 | 37 | 2002 |
First total synthesis and stereochemical revision of laxaphycin B and its extension to lyngbyacyclamide A F Boyaud, Z Mahiout, C Lenoir, S Tang, J Wdzieczak-Bakala, A Witczak, ... Organic letters 15 (15), 3898-3901, 2013 | 35 | 2013 |
Helical peptides from VEGF and Vammin hotspots for modulating the VEGF–VEGFR interaction MI García-Aranda, S González-López, CM Santiveri, N Gagey-Eilstein, ... Organic & Biomolecular Chemistry 11 (11), 1896-1905, 2013 | 33 | 2013 |
Isolation and Synthesis of Laxaphycin B-Type Peptides: A Case Study and Clues to Their Biosynthesis L Bornancin, F Boyaud, Z Mahiout, I Bonnard, SC Mills, B Banaigs, ... Marine drugs 13 (12), 7285-7300, 2015 | 29 | 2015 |
Toward an Optimal Joint Recognition of the S1‘ Subsites of Endothelin Converting Enzyme-1 (ECE-1), Angiotensin Converting Enzyme (ACE), and Neutral … N Inguimbert, P Coric, H Poras, H Meudal, F Teffot, MC Fournié-Zaluski, ... Journal of medicinal chemistry 45 (7), 1477-1486, 2002 | 29 | 2002 |
Structure and biological evaluation of new cyclic and acyclic laxaphycin-A type peptides L Bornancin, E Alonso, R Alvariño, N Inguimbert, I Bonnard, LM Botana, ... Bioorganic & Medicinal Chemistry 27 (10), 1966-1980, 2019 | 26 | 2019 |
Asp218 participates with Asp213 to bind a Ca2+ atom into the S1 subsite of aminopeptidase A: a key element for substrate specificity C Claperon, R Rozenfeld, X Iturrioz, N Inguimbert, M Okada, B Roques, ... Biochemical Journal 416 (1), 37-46, 2008 | 26 | 2008 |
Synthesis and in vitro activities of new non‐peptidic APA Inhibitors N Inguimbert, P Coric, H Dhotel, E Bonnard, C Llorens‐Cortes, N De Mota, ... The Journal of peptide research 65 (2), 175-188, 2005 | 26 | 2005 |
How are 1, 2, 3-triazoles accommodated in helical secondary structures? KBH Salah, S Das, N Ruiz, V Andreu, J Martinez, E Wenger, M Amblard, ... Organic & Biomolecular Chemistry 16 (19), 3576-3583, 2018 | 25 | 2018 |
Disulfide and amide-bridged cyclic peptide analogues of the VEGF81–91 fragment: Synthesis, conformational analysis and biological evaluation MI García-Aranda, Y Mirassou, B Gautier, M Martín-Martínez, N Inguimbert, ... Bioorganic & medicinal chemistry 19 (24), 7526-7533, 2011 | 25 | 2011 |
Efficient microwave-assisted one shot synthesis of peptaibols using inexpensive coupling reagents K Ben Haj Salah, N Inguimbert Organic letters 16 (6), 1783-1785, 2014 | 23 | 2014 |
Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF81–91: Potential biological tools for studying the VEGF/VEGFR-1 interaction MI García-Aranda, P Marrero, B Gautier, M Martín-Martínez, N Inguimbert, ... Bioorganic & medicinal chemistry 19 (6), 1978-1986, 2011 | 23 | 2011 |