Proteomic and lipidomic analysis of nanoparticle corona upon contact with lung surfactant reveals differences in protein, but not lipid composition SS Raesch, S Tenzer, W Storck, A Rurainski, D Selzer, CA Ruge, ... ACS nano 9 (12), 11872-11885, 2015 | 204 | 2015 |
Finite and infinite dosing: Difficulties in measurements, evaluations and predictions D Selzer, MMA Abdel-Mottaleb, T Hahn, UF Schaefer, D Neumann Advanced drug delivery reviews 65 (2), 278-294, 2013 | 157 | 2013 |
Towards drug quantification in human skin with confocal Raman microscopy L Franzen, D Selzer, JW Fluhr, UF Schaefer, M Windbergs European journal of pharmaceutics and biopharmaceutics 84 (2), 437-444, 2013 | 82 | 2013 |
Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects C Mathes, A Melero, P Conrad, T Vogt, L Rigo, D Selzer, WA Prado, ... Journal of Controlled Release 223, 207-214, 2016 | 80 | 2016 |
Data digitizing: accurate and precise data extraction for quantitative systems pharmacology and physiologically‐based pharmacokinetic modeling JG Wojtyniak, H Britz, D Selzer, M Schwab, T Lehr CPT: Pharmacometrics & Systems Pharmacology 9 (6), 322-331, 2020 | 71 | 2020 |
An extended database of keratin binding S Hansen, D Selzer, UF Schaefer, GB Kasting Journal of pharmaceutical sciences 100 (5), 1712-1726, 2011 | 57 | 2011 |
A comprehensive whole-body physiologically based pharmacokinetic drug–drug–gene interaction model of metformin and cimetidine in healthy adults and renally impaired individuals N Hanke, D Türk, D Selzer, N Ishiguro, T Ebner, S Wiebe, F Müller, ... Clinical Pharmacokinetics 59, 1419-1431, 2020 | 39 | 2020 |
Pharmacokinetics of the CYP3A4 and CYP2B6 inducer carbamazepine and its drug–drug interaction potential: a physiologically based pharmacokinetic modeling approach LM Fuhr, FZ Marok, N Hanke, D Selzer, T Lehr Pharmaceutics 13 (2), 270, 2021 | 36 | 2021 |
Physiologically-based pharmacokinetic (PBPK) modeling of buprenorphine in adults, children and preterm neonates L Kovar, C Schräpel, D Selzer, Y Kohl, R Bals, M Schwab, T Lehr Pharmaceutics 12 (6), 578, 2020 | 33 | 2020 |
Physiologically based precision dosing approach for drug‐drug‐gene interactions: a simvastatin network analysis JG Wojtyniak, D Selzer, M Schwab, T Lehr Clinical Pharmacology & Therapeutics 109 (1), 201-211, 2021 | 32 | 2021 |
Finite dose skin mass balance including the lateral part: comparison between experiment, pharmacokinetic modeling and diffusion models D Selzer, T Hahn, A Naegel, M Heisig, KH Kostka, CM Lehr, D Neumann, ... Journal of controlled release 165 (2), 119-128, 2013 | 30 | 2013 |
Physiologically based pharmacokinetic modeling of metoprolol enantiomers and α-hydroxymetoprolol to describe CYP2D6 drug-gene interactions S Rüdesheim, JG Wojtyniak, D Selzer, N Hanke, F Mahfoud, M Schwab, ... Pharmaceutics 12 (12), 1200, 2020 | 18 | 2020 |
External model performance evaluation of twelve infliximab population pharmacokinetic models in patients with inflammatory bowel disease C Schräpel, L Kovar, D Selzer, U Hofmann, F Tran, W Reinisch, ... Pharmaceutics 13 (9), 1368, 2021 | 17 | 2021 |
Mathematical models for dermal drug absorption D Selzer, D Neumann, UF Schaefer Expert opinion on drug metabolism & toxicology 11 (10), 1567-1583, 2015 | 17 | 2015 |
Influence of the application area on finite dose permeation in relation to drug type applied T Hahn, D Selzer, D Neumann, KH Kostka, CM Lehr, UF Schaefer Experimental dermatology 21 (3), 233-235, 2012 | 17 | 2012 |
Physiologically‐based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups S Rüdesheim, D Selzer, U Fuhr, M Schwab, T Lehr CPT: Pharmacometrics & Systems Pharmacology 11 (4), 494-511, 2022 | 16 | 2022 |
Physiologically-based pharmacokinetic (PBPK) modeling providing insights into fentanyl pharmacokinetics in adults and pediatric patients L Kovar, A Weber, M Zemlin, Y Kohl, R Bals, B Meibohm, D Selzer, T Lehr Pharmaceutics 12 (10), 908, 2020 | 16 | 2020 |
Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction … HLH Loer, D Türk, JD Gómez-Mantilla, D Selzer, T Lehr Pharmaceutics 14 (5), 915, 2022 | 14 | 2022 |
Novel models for the prediction of drug–gene interactions D Türk, LM Fuhr, FZ Marok, S Rüdesheim, A Kühn, D Selzer, M Schwab, ... Expert Opinion on Drug Metabolism & Toxicology 17 (11), 1293-1310, 2021 | 14 | 2021 |
Physiologically based pharmacokinetic modeling of bupropion and its metabolites in a CYP2B6 drug-drug-gene interaction network FZ Marok, LM Fuhr, N Hanke, D Selzer, T Lehr Pharmaceutics 13 (3), 331, 2021 | 14 | 2021 |