关注
Giorgio Saladino
Giorgio Saladino
在 ucl.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
The role of protein loops and linkers in conformational dynamics and allostery
E Papaleo, G Saladino, M Lambrughi, K Lindorff-Larsen, FL Gervasio, ...
Chemical reviews 116 (11), 6391-6423, 2016
3702016
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ...
Nature 561 (7721), 63-69, 2018
1702018
Understanding cryptic pocket formation in protein targets by enhanced sampling simulations
V Oleinikovas, G Saladino, BP Cossins, FL Gervasio
Journal of the American Chemical Society 138 (43), 14257-14263, 2016
1672016
Investigating drug–target association and dissociation mechanisms using metadynamics-based algorithms
A Cavalli, A Spitaleri, G Saladino, FL Gervasio
Accounts of chemical research 48 (2), 277-285, 2015
1512015
Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling
C Herbert, U Schieborr, K Saxena, J Juraszek, F De Smet, C Alcouffe, ...
Cancer cell 23 (4), 489-501, 2013
1362013
An efficient metadynamics-based protocol to model the binding affinity and the transition state ensemble of G-protein-coupled receptor ligands
N Saleh, P Ibrahim, G Saladino, FL Gervasio, T Clark
Journal of chemical information and modeling 57 (5), 1210-1217, 2017
1222017
Conformational selection and induced fit mechanisms in the binding of an anticancer drug to the c-Src kinase
MA Morando, G Saladino, N D’Amelio, E Pucheta-Martinez, S Lovera, ...
Scientific reports 6 (1), 24439, 2016
802016
Bidirectional allosteric communication between the ATP-binding site and the regulatory PIF pocket in PDK1 protein kinase
JO Schulze, G Saladino, K Busschots, S Neimanis, E Süß, D Odadzic, ...
Cell chemical biology 23 (10), 1193-1205, 2016
782016
Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells
Y Tsuchiya, A Zhyvoloup, J Baković, N Thomas, BYK Yu, S Das, C Orengo, ...
Biochemical Journal 475 (11), 1909-1937, 2018
712018
Towards a molecular understanding of the link between imatinib resistance and kinase conformational dynamics
S Lovera, M Morando, E Pucheta-Martinez, JL Martinez-Torrecuadrada, ...
PLoS computational biology 11 (11), e1004578, 2015
682015
Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations
A Kuzmanic, L Sutto, G Saladino, AR Nebreda, FL Gervasio, M Orozco
Elife 6, e22175, 2017
642017
An allosteric cross-talk between the activation loop and the ATP binding site regulates the activation of Src kinase
E Pucheta-Martínez, G Saladino, MA Morando, J Martinez-Torrecuadrada, ...
Scientific Reports 6 (1), 24235, 2016
512016
Efficient Numerical Reconstruction of Protein Folding Kinetics with Partial Path Sampling<? format?> and Pathlike Variables
J Juraszek, G Saladino, TS Van Erp, FL Gervasio
Physical Review Letters 110 (10), 108106, 2013
512013
Assessing the performance of metadynamics and path variables in predicting the binding free energies of p38 inhibitors
G Saladino, L Gauthier, M Bianciotto, FL Gervasio
Journal of Chemical Theory and Computation 8 (4), 1165-1170, 2012
502012
A three‐site mechanism for agonist/antagonist selective binding to vasopressin receptors
N Saleh, G Saladino, FL Gervasio, E Haensele, L Banting, DC Whitley, ...
Angewandte Chemie 128 (28), 8140-8144, 2016
472016
The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor
M Sahún‐Roncero, B Rubio‐Ruiz, G Saladino, A Conejo‐García, ...
Angewandte Chemie International Edition 52 (17), 4582-4586, 2013
472013
Assessment of the model refinement category in CASP12
L Hovan, V Oleinikovas, H Yalinca, A Kryshtafovych, G Saladino, ...
PROTEINS: structure, function, and bioinformatics 86, 152-167, 2018
462018
In silico design of tubulin-targeted antimitotic peptides
S Pieraccini, G Saladino, G Cappelletti, D Cartelli, P Francescato, ...
Nature chemistry 1 (8), 642-648, 2009
462009
Investigating allosteric effects on the functional dynamics of β2-adrenergic ternary complexes with enhanced-sampling simulations
N Saleh, G Saladino, FL Gervasio, T Clark
Chemical Science 8 (5), 4019-4026, 2017
382017
A multiscale simulation approach to modeling drug–protein binding kinetics
S Haldar, F Comitani, G Saladino, C Woods, MW van der Kamp, ...
Journal of chemical theory and computation 14 (11), 6093-6101, 2018
332018
系统目前无法执行此操作,请稍后再试。
文章 1–20