Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation RJ Johnston, AC Poholek, D DiToro, I Yusuf, D Eto, B Barnett, AL Dent, ... Science 325 (5943), 1006-1010, 2009 | 1861 | 2009 |
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid MLJ Watson, PDA Vignali, SJ Mullett, AE Overacre-Delgoffe, RM Peralta, ... Nature 591 (7851), 645-651, 2021 | 641 | 2021 |
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity JM Odegard, BR Marks, LD DiPlacido, AC Poholek, DH Kono, C Dong, ... The Journal of experimental medicine 205 (12), 2873-2886, 2008 | 471 | 2008 |
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion NE Scharping, DB Rivadeneira, AV Menk, PDA Vignali, BR Ford, ... Nature immunology 22 (2), 205-215, 2021 | 452 | 2021 |
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion DV Sawant, H Yano, M Chikina, Q Zhang, M Liao, C Liu, DJ Callahan, ... Nature immunology 20 (6), 724-735, 2019 | 391 | 2019 |
CD4 T follicular helper cell dynamics during SIV infection C Petrovas, T Yamamoto, MY Gerner, KL Boswell, K Wloka, EC Smith, ... The Journal of clinical investigation 122 (9), 3281-3294, 2012 | 371 | 2012 |
In vivo regulation of Bcl6 and T follicular helper cell development AC Poholek, K Hansen, SG Hernandez, D Eto, A Chandele, JS Weinstein, ... The Journal of immunology 185 (1), 313-326, 2010 | 344 | 2010 |
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4+ cell properties during viral infection HD Marshall, A Chandele, YW Jung, H Meng, AC Poholek, IA Parish, ... Immunity 35 (4), 633-646, 2011 | 340 | 2011 |
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease K Hirahara, A Poholek, G Vahedi, A Laurence, Y Kanno, JD Milner, ... Journal of allergy and clinical immunology 131 (5), 1276-1287, 2013 | 231 | 2013 |
Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation BR Marks, HN Nowyhed, JY Choi, AC Poholek, JM Odegard, RA Flavell, ... Nature immunology 10 (10), 1125-1132, 2009 | 204 | 2009 |
IL-23 and IL-1β drive human Th17 cell differentiation and metabolic reprogramming in absence of CD28 costimulation S Revu, J Wu, M Henkel, N Rittenhouse, A Menk, GM Delgoffe, ... Cell reports 22 (10), 2642-2653, 2018 | 196 | 2018 |
Distinct requirements for T-bet in gut innate lymphoid cells G Sciumè, K Hirahara, H Takahashi, A Laurence, AV Villarino, ... Journal of Experimental Medicine 209 (13), 2331-2338, 2012 | 188 | 2012 |
Helper T‐cell identity and evolution of differential transcriptomes and epigenomes G Vahedi, A C. Poholek, TW Hand, A Laurence, Y Kanno, JJ O'Shea, ... Immunological reviews 252 (1), 24-40, 2013 | 132 | 2013 |
Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program S Nakayamada, AC Poholek, KT Lu, H Takahashi, M Kato, S Iwata, ... The Journal of Immunology 192 (5), 2156-2166, 2014 | 127 | 2014 |
A vesicular stomatitis virus recombinant expressing granulocyte-macrophage colony-stimulating factor induces enhanced T-cell responses and is highly attenuated for replication … E Ramsburg, J Publicover, L Buonocore, A Poholek, M Robek, A Palin, ... Journal of virology 79 (24), 15043-15053, 2005 | 121 | 2005 |
Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity PDA Vignali, K DePeaux, MLJ Watson, C Ye, BR Ford, K Lontos, ... Nature immunology 24 (2), 267-279, 2023 | 107 | 2023 |
Transcriptional and epigenetic networks of helper T and innate lymphoid cells HY Shih, G Sciumè, AC Poholek, G Vahedi, K Hirahara, AV Villarino, ... Immunological Reviews 261 (1), 23-49, 2014 | 100 | 2014 |
Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis S Zhang, TN Edwards, VK Chaudhri, J Wu, JA Cohen, T Hirai, ... Cell 184 (8), 2151-2166. e16, 2021 | 97 | 2021 |
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival S Majumder, N Amatya, S Revu, CV Jawale, D Wu, N Rittenhouse, ... Nature immunology 20 (5), 534-545, 2019 | 85 | 2019 |
Identification of binding sites of EVI1 in mammalian cells B Yatsula, S Lin, AJ Read, A Poholek, K Yates, D Yue, P Hui, AS Perkins Journal of Biological Chemistry 280 (35), 30712-30722, 2005 | 81 | 2005 |