A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila CH Chen, H Huang, CM Ward, JT Su, LV Schaeffer, M Guo, BA Hay science 316 (5824), 597-600, 2007 | 383 | 2007 |
Novel biodegradable porous scaffold applied to skin regeneration HM Wang, YT Chou, ZH Wen, ZR Wang, CH Chen, ML Ho PloS one 8 (6), e56330, 2013 | 212 | 2013 |
Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in Drosophila SE Siegrist, NS Haque, CH Chen, BA Hay, IK Hariharan Current Biology 20 (7), 643-648, 2010 | 200 | 2010 |
Twin-spot MARCM to reveal the developmental origin and identity of neurons HH Yu, CH Chen, L Shi, Y Huang, T Lee Nature neuroscience 12 (7), 947-953, 2009 | 170 | 2009 |
The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process I Muro, DL Berry, JR Huh, CH Chen, H Huang, SJ Yoo, M Guo, ... Oxford University Press for The Company of Biologists Limited 133 (17), 3305 …, 2006 | 168 | 2006 |
The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be … JR Huh, I Foe, I Muro, CH Chen, JH Seol, SJ Yoo, M Guo, JM Park, ... Journal of Biological Chemistry 282 (3), 2056-2068, 2007 | 120 | 2007 |
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy P Sun, K Nie, Y Zhu, Y Liu, P Wu, Z Liu, S Du, H Fan, CH Chen, R Zhang, ... Nature communications 11 (1), 260, 2020 | 117 | 2020 |
Engineered resistance to Zika virus in transgenic Aedes aegypti expressing a polycistronic cluster of synthetic small RNAs A Buchman, S Gamez, M Li, I Antoshechkin, HH Li, HW Wang, CH Chen, ... Proceedings of the National Academy of Sciences 116 (9), 3656-3661, 2019 | 113 | 2019 |
Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing WY Tsai, YT Chow, HR Chen, KT Huang, RI Hong, SP Jan, NY Kuo, ... Journal of Biological Chemistry 274 (14), 9455-9462, 1999 | 113 | 1999 |
Atg9 interacts with dTRAF2/TRAF6 to regulate oxidative stress-induced JNK activation and autophagy induction HW Tang, HM Liao, WH Peng, HR Lin, CH Chen, GC Chen Developmental cell 27 (5), 489-503, 2013 | 112 | 2013 |
Novel Synthetic Medea Selfish Genetic Elements Drive Population Replacement in Drosophila; a Theoretical Exploration of Medea-Dependent Population … OS Akbari, CH Chen, JM Marshall, H Huang, I Antoshechkin, BA Hay ACS synthetic biology 3 (12), 915-928, 2014 | 106 | 2014 |
Broad dengue neutralization in mosquitoes expressing an engineered antibody A Buchman, S Gamez, M Li, I Antoshechkin, HH Li, HW Wang, CH Chen, ... PLoS pathogens 16 (1), e1008103, 2020 | 102 | 2020 |
The role of the PI3K/Akt/mTOR pathway in glial scar formation following spinal cord injury CH Chen, CS Sung, SY Huang, CW Feng, HC Hung, SN Yang, NF Chen, ... Experimental Neurology 278, 27-41, 2016 | 91 | 2016 |
Built-in radiation structure for a millimeter wave radar sensor CHH Chen, HSE Tsou US Patent 5,512,901, 1996 | 89 | 1996 |
Necrosis-driven systemic immune response alters SAM metabolism through the FOXO-GNMT axis F Obata, E Kuranaga, K Tomioka, M Ming, A Takeishi, CH Chen, T Soga, ... Cell reports 7 (3), 821-833, 2014 | 87 | 2014 |
Functional and physical interactions between components of the Prp19p-associated complex CH Chen, WC Yu, TY Tsao, LY Wang, HR Chen, JY Lin, WY Tsai, ... Nucleic Acids Research 30 (4), 1029-1037, 2002 | 86 | 2002 |
Core commitments for field trials of gene drive organisms KC Long, L Alphey, GJ Annas, CS Bloss, KJ Campbell, J Champer, ... Science 370 (6523), 1417-1419, 2020 | 81 | 2020 |
Stage-specific differences in the requirements for germline stem cell maintenance in the Drosophila ovary HR Shcherbata, EJ Ward, KA Fischer, JY Yu, SH Reynolds, CH Chen, ... Cell stem cell 1 (6), 698-709, 2007 | 76 | 2007 |
Multiple scanning beam direct radiating array and method for its use BR Allen, KT Yano, CHH Chen US Patent 6,005,515, 1999 | 72 | 1999 |
Engineering the genomes of wild insect populations: challenges, and opportunities provided by synthetic Medea selfish genetic elements BA Hay, CH Chen, CM Ward, H Huang, JT Su, M Guo Journal of Insect Physiology 56 (10), 1402-1413, 2010 | 70 | 2010 |