High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ... science 318 (5854), 1258-1265, 2007 | 4085 | 2007 |
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist VP Jaakola, MT Griffith, MA Hanson, V Cherezov, EYT Chien, JR Lane, ... Science 322 (5905), 1211-1217, 2008 | 2235 | 2008 |
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ... science 318 (5854), 1266-1273, 2007 | 1754 | 2007 |
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist EYT Chien, W Liu, Q Zhao, V Katritch, G Won Han, MA Hanson, L Shi, ... Science 330 (6007), 1091-1095, 2010 | 1345 | 2010 |
A specific cholesterol binding site is established by the 2.8 Å structure of the human β2-adrenergic receptor MA Hanson, V Cherezov, MT Griffith, CB Roth, VP Jaakola, EYT Chien, ... Structure 16 (6), 897-905, 2008 | 1136 | 2008 |
Crystal structure of a lipid G protein–coupled receptor MA Hanson, CB Roth, E Jo, MT Griffith, FL Scott, G Reinhart, H Desale, ... Science 335 (6070), 851-855, 2012 | 803 | 2012 |
Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling MH Bracey, MA Hanson, KR Masuda, RC Stevens, BF Cravatt Science 298 (5599), 1793-1796, 2002 | 614 | 2002 |
Crystal structure of the human cannabinoid receptor CB1 T Hua, K Vemuri, M Pu, L Qu, GW Han, Y Wu, S Zhao, W Shui, S Li, ... Cell 167 (3), 750-762. e14, 2016 | 573 | 2016 |
Microscale fluorescent thermal stability assay for membrane proteins AI Alexandrov, M Mileni, EYT Chien, MA Hanson, RC Stevens Structure 16 (3), 351-359, 2008 | 539 | 2008 |
Crystal structures of agonist-bound human cannabinoid receptor CB1 T Hua, K Vemuri, SP Nikas, RB Laprairie, Y Wu, L Qu, M Pu, A Korde, ... Nature 547 (7664), 468-471, 2017 | 481 | 2017 |
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors E Chun, AA Thompson, W Liu, CB Roth, MT Griffith, V Katritch, J Kunken, ... Structure 20 (6), 967-976, 2012 | 444 | 2012 |
Discovery of new GPCR biology: one receptor structure at a time MA Hanson, RC Stevens Structure 17 (1), 8-14, 2009 | 260 | 2009 |
5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ... Cell 172 (4), 719-730. e14, 2018 | 231 | 2018 |
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence H Rosen, RC Stevens, M Hanson, E Roberts, MBA Oldstone Annual review of biochemistry 82 (1), 637-662, 2013 | 229 | 2013 |
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators G Song, D Yang, Y Wang, C De Graaf, Q Zhou, S Jiang, K Liu, X Cai, ... Nature 546 (7657), 312-315, 2017 | 228 | 2017 |
Structure of the full-length glucagon class B G-protein-coupled receptor H Zhang, A Qiao, D Yang, L Yang, A Dai, C De Graaf, S Reedtz-Runge, ... Nature 546 (7657), 259-264, 2017 | 207 | 2017 |
Crystal structure of antagonist bound human lysophosphatidic acid receptor 1 JE Chrencik, CB Roth, M Terakado, H Kurata, R Omi, Y Kihara, ... Cell 161 (7), 1633-1643, 2015 | 205 | 2015 |
Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 Å resolution MA Hanson, RC Stevens nature structural biology 7 (8), 687-692, 2000 | 191 | 2000 |
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 µm size X-ray synchrotron beam V Cherezov, MA Hanson, MT Griffith, MC Hilgart, R Sanishvili, ... Journal of The Royal Society Interface 6 (suppl_5), S587-S597, 2009 | 178 | 2009 |
Stabilization of the human β2-adrenergic receptor TM4–TM3–TM5 helix interface by mutagenesis of Glu1223. 41, a critical residue in GPCR structure CB Roth, MA Hanson, RC Stevens Journal of molecular biology 376 (5), 1305-1319, 2008 | 166 | 2008 |