ErbB family receptor inhibitors as therapeutic agents in breast cancer: current status and future clinical perspective R Saxena, A Dwivedi Medicinal research reviews 32 (1), 166-215, 2012 | 125 | 2012 |
(−)-Epigallocatechin-3-gallate induces apoptosis in human endometrial adenocarcinoma cells via ROS generation and p38 MAP kinase activation M Manohar, I Fatima, R Saxena, V Chandra, PL Sankhwar, A Dwivedi The Journal of nutritional biochemistry 24 (6), 940-947, 2013 | 71 | 2013 |
Design and synthesis of new bioisosteres of spirooxindoles (MI-63/219) as anti-breast cancer agents A Kumar, G Gupta, AK Bishnoi, R Saxena, KS Saini, R Konwar, S Kumar, ... Bioorganic & Medicinal Chemistry 23 (4), 839-848, 2015 | 65 | 2015 |
Design and synthesis of ERα/ERβ selective coumarin and chromene derivatives as potential anti-breast cancer and anti-osteoporotic agents MK Hussain, MI Ansari, N Yadav, PK Gupta, AK Gupta, R Saxena, ... RSC Advances 4 (17), 8828-8845, 2014 | 65 | 2014 |
ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma P Khanna, HJ Soh, CH Chen, R Saxena, S Amin, M Naughton, PN Joslin, ... Science translational medicine 13 (577), eabc0170, 2021 | 37 | 2021 |
Novel diastereoselective synthesis of spiropyrrolidine-oxindole derivatives as anti-breast cancer agents A Kumar, G Gupta, S Srivastava, AK Bishnoi, R Saxena, R Kant, ... RSC advances 3 (14), 4731-4735, 2013 | 28 | 2013 |
Design and synthesis of 1, 3-biarylsulfanyl derivatives as new anti-breast cancer agents A Kumar, VD Tripathi, P Kumar, LP Gupta, R Trivedi, H Bid, VL Nayak, ... Bioorganic & medicinal chemistry 19 (18), 5409-5419, 2011 | 27 | 2011 |
2, 3-Diaryl-2H-1-benzopyran derivatives interfere with classical and non-classical estrogen receptor signaling pathways, inhibit Akt activation and induce apoptosis in human … I Fatima, V Chandra, R Saxena, M Manohar, Y Sanghani, K Hajela, ... Molecular and cellular endocrinology 348 (1), 198-210, 2012 | 21 | 2012 |
CXCR4 inhibition modulates the tumor microenvironment and retards the growth of B16-OVA melanoma and Renca tumors R Saxena, Y Wang, JW Mier Melanoma research 30 (1), 14-25, 2020 | 20 | 2020 |
Study of Cathepsin B Inhibition in VEGFR TKI Treated Human Renal Cell Carcinoma Xenografts. MBRSB Chun-Hau Chen, Swati Bhasin, Prateek Khanna, Mukta Joshi, Patrick MN ... Oncogenesis 8 (15), 2019 | 19 | 2019 |
Spiro-oxindole derivative 5-chloro-4′, 5′-diphenyl-3′-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro [indoline-3, 2′-pyrrolidin]-2-one triggers apoptosis in breast cancer … R Saxena, G Gupta, M Manohar, U Debnath, P Popli, YS Prabhakar, ... The International Journal of Biochemistry & Cell Biology 70, 105-117, 2016 | 18 | 2016 |
The anti-proliferative effect of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo (b) pyran is potentiated via induction of estrogen receptor beta and p21 in human … I Fatima, R Saxena, G Kharkwal, MK Hussain, N Yadav, K Hajela, ... The Journal of Steroid Biochemistry and Molecular Biology 138, 123-131, 2013 | 18 | 2013 |
Expression of estrogen receptor co-regulators SRC-1, RIP140 and NCoR and their interaction with estrogen receptor in rat uterus, under the influence of ormeloxifene A Daverey, R Saxena, S Tewari, SK Goel, A Dwivedi The Journal of steroid biochemistry and molecular biology 116 (1-2), 93-101, 2009 | 18 | 2009 |
Apoptosis induction and inhibition of hyperplasia formation by 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo (b) pyran in rat uterus V Chandra, I Fatima, R Saxena, S Kitchlu, S Sharma, MK Hussain, ... American Journal of Obstetrics and Gynecology 205 (4), 362. e1-362. e11, 2011 | 16 | 2011 |
Anti-tumorigenic action of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo (b) pyran: Evidence for involvement of GPR30/EGFR signaling pathway V Chandra, I Fatima, R Saxena, MK Hussain, K Hajela, P Sankhwar, ... Gynecologic oncology 129 (2), 433-442, 2013 | 12 | 2013 |
Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α-and β-mediated signaling, in … R Saxena, I Fatima, V Chandra, CS Blesson, G Kharkwal, MK Hussain, ... Steroids 78 (11), 1071-1086, 2013 | 9 | 2013 |
3-Piperidylethoxypterocarpan: A potential bone anabolic agent that improves bone quality and restores trabecular micro-architecture in ovariectomized osteopenic rats A Raghuvanshi, A Kumar, AM Tyagi, J Kureel, P Awasthi, D Purohit, ... Molecular and Cellular Endocrinology 448, 41-54, 2017 | 7 | 2017 |
Antitumor immune mechanisms of the anti-complement factor H antibody GT103 RT Bushey, R Saxena, MJ Campa, EB Gottlin, YW He, EF Patz Jr Molecular Cancer Therapeutics 22 (6), 778-789, 2023 | 4 | 2023 |
Class I PI3K provide lipid substrate in T cell autophagy through linked activity of inositol phosphatases IX McLeod, R Saxena, Z Carico, YW He Frontiers in Cell and Developmental Biology 9, 709398, 2021 | 3 | 2021 |
CXCR4 inhibition modulates tumor microenvironment and robustly inhibits growth of B16-OVA melanoma R Saxena, Y Wang, JW Mier Cancer Research 78 (13_Supplement), 1749-1749, 2018 | 3 | 2018 |