Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... Neuron 84 (6), 1213-1225, 2014 | 584 | 2014 |
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 579 | 2018 |
Molecular basis for sculpting the endoplasmic reticulum membrane S Lin, S Sun, J Hu The international journal of biochemistry & cell biology 44 (9), 1436-1443, 2012 | 60 | 2012 |
Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 proteins Y Feng, W Yu, X Li, S Lin, Y Zhou, J Hu, X Liu Journal of Biological Chemistry 288 (39), 28418-28427, 2013 | 58 | 2013 |
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ... JCI insight 4 (15), 2019 | 55 | 2019 |
Sec61β facilitates the maintenance of endoplasmic reticulum homeostasis by associating microtubules Y Zhu, G Zhang, S Lin, J Shi, H Zhang, J Hu Protein & Cell 9 (7), 616-628, 2018 | 29 | 2018 |
Small molecule inhibition of PIKFYVE kinase rescues gain- and loss-of-function C9ORF72 ALS/FTD disease processes in vivo KA Staats, C Seah, A Sahimi, Y Wang, N Koutsodendris, S Lin, D Kim, ... BioRxiv, 685800, 2019 | 22 | 2019 |
Engineering skeletal muscle tissues with advanced maturity improves synapse formation with human induced pluripotent stem cell-derived motor neurons JW Santoso, X Li, D Gupta, GC Suh, E Hendricks, S Lin, S Perry, JK Ichida, ... APL bioengineering 5 (3), 2021 | 16 | 2021 |
Antisense proline-arginine RAN dipeptides linked to X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... C9ORF72, 0 | 11 | |
Methods to treat neurological diseases J Ichida, S Lin, Y Li, Y Shi US Patent 10,758,545, 2020 | 2 | 2020 |
Haploinsufficiency for Guanine Exchange Factor Activity Leads to Neurodegeneration in C9ORF72 ALS/FTD Y Shi, S Lin, J Ichida MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 Y Feng, W Yu, X Li, S Lin, Y Zhou, J Hu, X Liu | | 2013 |
PLEASE CITE THIS ARTICLE AS DOI: 10.1063/5.0054984 JW Santoso, X Li, D Gupta, GC Suh, E Hendricks, S Lin, S Perry, JK Ichida, ... | | |