Origins and proliferative states of human oligodendrocyte precursor cells W Huang, A Bhaduri, D Velmeshev, S Wang, L Wang, CA Rottkamp, ... Cell 182 (3), 594-608. e11, 2020 | 148 | 2020 |
A mild PUM1 mutation is associated with adult-onset ataxia, whereas haploinsufficiency causes developmental delay and seizures VA Gennarino, EE Palmer, LM McDonell, L Wang, CJ Adamski, A Koire, ... Cell 172 (5), 924-936. e11, 2018 | 132 | 2018 |
Tropism of SARS-CoV-2 for human cortical astrocytes MG Andrews, T Mukhtar, UC Eze, CR Simoneau, J Ross, N Parikshak, ... Proceedings of the National Academy of Sciences 119 (30), e2122236119, 2022 | 92 | 2022 |
Otud7a knockout mice recapitulate many neurological features of 15q13. 3 microdeletion syndrome J Yin, W Chen, ES Chao, S Soriano, L Wang, W Wang, SE Cummock, ... The American Journal of Human Genetics 102 (2), 296-308, 2018 | 73 | 2018 |
An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function L Wang, K Pang, K Han, CJ Adamski, W Wang, L He, JK Lai, VV Bondar, ... Molecular psychiatry 25 (10), 2534-2555, 2020 | 69 | 2020 |
Single-cell analysis of prenatal and postnatal human cortical development D Velmeshev, Y Perez, Z Yan, JE Valencia, DR Castaneda-Castellanos, ... Science 382 (6667), eadf0834, 2023 | 33 | 2023 |
A kinome-wide RNAi screen identifies ERK2 as a druggable regulator of Shank3 stability L Wang, CJ Adamski, VV Bondar, E Craigen, JR Collette, K Pang, K Han, ... Molecular psychiatry 25 (10), 2504-2516, 2020 | 26 | 2020 |
Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions X Meng, CM McGraw, W Wang, J Jing, SY Yeh, L Wang, J Lopez, ... Elife 8, e46773, 2019 | 24 | 2019 |
PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in Spinocerebellar ataxia type 1 VV Bondar, CJ Adamski, TS Onur, Q Tan, L Wang, J Diaz-Garcia, J Park, ... Human molecular genetics, 2018 | 24 | 2018 |
A cross-species proteomic map reveals neoteny of human synapse development L Wang†, K Pang, L Zhou, A Cebrián-Silla, S González-Granero, S Wang, ... Nature 622 (7981), 112-119, 2023 | 20 | 2023 |
Phospholipid‐flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure T Li, D Yu, HC Oak, B Zhu, L Wang, X Jiang, RS Molday, A Kriegstein, ... The EMBO Journal 40 (21), e107915, 2021 | 19 | 2021 |
Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal … CA Chen, W Wang, SE Pedersen, A Raman, ML Seymour, FR Ruiz, A Xia, ... Human Molecular Genetics 29 (5), 705-715, 2020 | 17 | 2020 |
Coexpression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders K Pang*, L Wang*, W Wang, J Zhou, C Cheng, K Han, HY Zoghbi, Z Liu Genome Research 30 (6), 835-848, 2020 | 14 | 2020 |
LIF signaling regulates outer radial glial to interneuron fate during human cortical development MG Andrews*, C Siebert*, L Wang*, ML White, J Ross, R Morales, ... Cell stem cell 30 (10), 1382-1391. e5, 2023 | 13 | 2023 |
Mitochondria control cortical cell fate after mitosis L Wang, A Kriegstein Developmental Cell 55 (2), 120-122, 2020 | 5 | 2020 |
A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation L Wang†, K Pang, L Zhou, A Cebrián-Silla, S González-Granero, S Wang, ... bioRxiv, 2022.10. 24.513541, 2022 | 2 | 2022 |
Identifying genetics-based mechanisms and treatments for neurodevelopmental and psychiatric disorders through data integration K Pang, L Wang, S Chang Frontiers in Genetics 14, 1186489, 2023 | 1 | 2023 |
A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex XG Liang, K Hoang, BL Meyerink, P Kc, K Paraiso, L Wang, IR Jones, ... Proceedings of the National Academy of Sciences 121 (20), e2321711121, 2024 | | 2024 |
Molecular and cellular dynamics of the developing human neocortex at single-cell resolution L Wang*†, C Wang*, JA Moriano, S Chen, S Zhang, T Mukhtar, S Wang, ... bioRxiv, 2024.01. 16.575956, 2024 | | 2024 |
Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism Y Perez, D Velmeshev, L Wang, M White, C Siebert, J Baltazar, NG Dutton, ... bioRxiv, 2023 | | 2023 |