Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction S Oddo, A Caccamo, JD Shepherd, MP Murphy, TE Golde, R Kayed, ... Neuron 39 (3), 409-421, 2003 | 4894 | 2003 |
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer’s disease S Oddo, A Caccamo, M Kitazawa, BP Tseng, FM LaFerla Neurobiology of aging 24 (8), 1063-1070, 2003 | 1251 | 2003 |
Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-β, and Tau: effects on cognitive impairments A Caccamo, S Majumder, A Richardson, R Strong, S Oddo Journal of Biological Chemistry 285 (17), 13107-13120, 2010 | 992 | 2010 |
M1 receptors play a central role in modulating AD-like pathology in transgenic mice A Caccamo, S Oddo, LM Billings, KN Green, H Martinez-Coria, A Fisher, ... Neuron 49 (5), 671-682, 2006 | 528 | 2006 |
Temporal profile of amyloid-β (Aβ) oligomerization in an in vivo model of Alzheimer disease: a link between Aβ and tau pathology S Oddo, A Caccamo, L Tran, MP Lambert, CG Glabe, WL Klein, ... Journal of Biological Chemistry 281 (3), 1599-1604, 2006 | 522 | 2006 |
Reduction of soluble Aβ and tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles S Oddo, V Vasilevko, A Caccamo, M Kitazawa, DH Cribbs, FM LaFerla Journal of Biological Chemistry 281 (51), 39413-39423, 2006 | 416 | 2006 |
Age-and region-dependent alterations in Aβ-degrading enzymes: implications for Aβ-induced disorders A Caccamo, S Oddo, MC Sugarman, Y Akbari, FM LaFerla Neurobiology of aging 26 (5), 645-654, 2005 | 402 | 2005 |
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies A Caccamo, A Magrì, DX Medina, EV Wisely, MF López‐Aranda, AJ Silva, ... Aging cell 12 (3), 370-380, 2013 | 391 | 2013 |
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice GE Stutzmann, I Smith, A Caccamo, S Oddo, FM LaFerla, I Parker Journal of Neuroscience 26 (19), 5180-5189, 2006 | 384 | 2006 |
Necroptosis activation in Alzheimer's disease A Caccamo, C Branca, IS Piras, E Ferreira, MJ Huentelman, WS Liang, ... Nature neuroscience 20 (9), 1236-1246, 2017 | 362 | 2017 |
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice LK Clinton, LM Billings, KN Green, A Caccamo, J Ngo, S Oddo, ... Neurobiology of disease 28 (1), 76-82, 2007 | 360 | 2007 |
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered … GE Stutzmann, A Caccamo, FM LaFerla, I Parker Journal of Neuroscience 24 (2), 508-513, 2004 | 329 | 2004 |
A dynamic relationship between intracellular and extracellular pools of Aβ S Oddo, A Caccamo, IF Smith, KN Green, FM LaFerla The American journal of pathology 168 (1), 184-194, 2006 | 306 | 2006 |
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease A Caccamo, MA Maldonado, AF Bokov, S Majumder, S Oddo Proceedings of the National Academy of Sciences 107 (52), 22687-22692, 2010 | 277 | 2010 |
Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease S Oddo, A Caccamo, KN Green, K Liang, L Tran, Y Chen, FM Leslie, ... Proceedings of the National Academy of Sciences 102 (8), 3046-3051, 2005 | 264 | 2005 |
Methylene blue reduces Aβ levels and rescues early cognitive deficit by increasing proteasome activity DX Medina, A Caccamo, S Oddo Brain pathology 21 (2), 140-149, 2011 | 250 | 2011 |
Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice R Belfiore, A Rodin, E Ferreira, R Velazquez, C Branca, A Caccamo, ... Aging cell 18 (1), e12873, 2019 | 243 | 2019 |
Lithium reduces tau phosphorylation but not Aβ or working memory deficits in a transgenic model with both plaques and tangles A Caccamo, S Oddo, LX Tran, FM LaFerla The American journal of pathology 170 (5), 1669-1675, 2007 | 243 | 2007 |
Lifelong rapamycin administration ameliorates age‐dependent cognitive deficits by reducing IL‐1β and enhancing NMDA signaling S Majumder, A Caccamo, DX Medina, AD Benavides, MA Javors, E Kraig, ... Aging cell 11 (2), 326-335, 2012 | 231 | 2012 |
Naturally secreted amyloid-β increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism A Caccamo, MA Maldonado, S Majumder, DX Medina, W Holbein, ... Journal of Biological Chemistry 286 (11), 8924-8932, 2011 | 202 | 2011 |