A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ... Cancer discovery 3 (12), 1364-1377, 2013 | 394 | 2013 |
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks D Palmieri, PR Lockman, FC Thomas, E Hua, J Herring, E Hargrave, ... Clinical Cancer Research 15 (19), 6148-6157, 2009 | 176 | 2009 |
Elevated NSD3 histone methylation activity drives squamous cell lung cancer G Yuan, NM Flores, S Hausmann, SM Lofgren, V Kharchenko, ... Nature 590 (7846), 504-508, 2021 | 95 | 2021 |
Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer N Reynoird, PK Mazur, T Stellfeld, NM Flores, SM Lofgren, SM Carlson, ... Genes & development 30 (7), 772-785, 2016 | 88 | 2016 |
DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer S Woditschka, L Evans, R Duchnowska, LT Reed, D Palmieri, Y Qian, ... JNCI: Journal of the National Cancer Institute 106 (7), dju145, 2014 | 86 | 2014 |
SETD5-coordinated chromatin reprogramming regulates adaptive resistance to targeted pancreatic cancer therapy Z Wang, S Hausmann, R Lyu, TM Li, SM Lofgren, NM Flores, ME Fuentes, ... Cancer cell 37 (6), 834-849. e13, 2020 | 70 | 2020 |
Essential role for the planarian intestinal GATA transcription factor in stem cells and regeneration NM Flores, NJ Oviedo, J Sage Developmental Biology 418 (1), 179-188, 2016 | 41 | 2016 |
The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas K Valencia, O Erice, K Kostyrko, S Hausmann, E Guruceaga, A Tathireddy, ... The Journal of clinical investigation 130 (4), 1879-1895, 2020 | 33 | 2020 |
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer G Gao, S Hausmann, NM Flores, AM Benitez, J Shen, X Yang, MD Person, ... Nature communications 14 (1), 363, 2023 | 25 | 2023 |
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities C Xu, KK Huang, JH Law, JS Chua, T Sheng, NM Flores, MP Pizzi, ... Gut 72 (9), 1651-1663, 2023 | 11 | 2023 |
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discov 3: 1364–1377. doi: 10 … NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ... CD-13-0183, 2013 | 11 | 2013 |
Altered response to antidepressant treatment in FoxG1 heterozygous knockout mice R Kinsler, MM Taylor, NM Flores, JJ Leffert, RD Beech Synapse 64 (2), 169-171, 2010 | 9 | 2010 |
13-gene signature to predict rapid development of brain metastases in patients with HER2-positive advanced breast cancer. R Duchnowska, J Jassem, CP Goswami, Y Gokmen-Polar, L Li, ... Journal of Clinical Oncology 30 (15_suppl), 505-505, 2012 | 8 | 2012 |
RAD51 and brain metastases (BM) in patients (pts) with HER2+ breast cancer. R Duchnowska, J Jassem, E Szutowicz, W Biernat, T Jankowski, W Och, ... Journal of Clinical Oncology 29 (15_suppl), 634-634, 2011 | 3 | 2011 |
Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis AG Casanova, GS Roth, S Hausmann, X Lu, LJM Bischoff, EM Froeliger, ... Cell Discovery 10 (1), 12, 2024 | 2 | 2024 |
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer J Park, J Wu, KJ Szkop, J Jeong, P Jovanovic, D Husmann, NM Flores, ... Nature, 1-8, 2024 | 1 | 2024 |
Author Correction: Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis. AG Casanova, GS Roth, S Hausmann, X Lu, LJM Bischoff, EM Froeliger, ... Cell Discovery 10 (1), 2024 | 1 | 2024 |
SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma B Miao, L Ge, C He, X Wang, J Wu, X Li, K Chen, J Wan, S Xing, L Ren, ... Cell research, 1-13, 2024 | | 2024 |
Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response X Cheng, E Dai, J Wu, NM Flores, Y Chu, R Wang, M Dang, Z Xu, G Han, ... Gastroenterology, 2024 | | 2024 |
FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis JW Francis, S Hausmann, S Ikram, K Yin, R Mealey-Farr, NM Flores, ... Molecular cell 84 (9), 1753-1763. e7, 2024 | | 2024 |