Regulation of ferroptotic cancer cell death by GPX4 WS Yang, R SriRamaratnam, ME Welsch, K Shimada, R Skouta, ... Cell 156 (1), 317-331, 2014 | 5132 | 2014 |
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis SJ Dixon, DN Patel, M Welsch, R Skouta, ED Lee, M Hayano, AG Thomas, ... elife 3, e02523, 2014 | 1626 | 2014 |
Privileged scaffolds for library design and drug discovery ME Welsch, SA Snyder, BR Stockwell Current opinion in chemical biology 14 (3), 347-361, 2010 | 1626 | 2010 |
Multivalent small-molecule pan-RAS inhibitors ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ... Cell 168 (5), 878-889. e29, 2017 | 267 | 2017 |
Modulatory profiling identifies mechanisms of small molecule-induced cell death AJ Wolpaw, K Shimada, R Skouta, ME Welsch, UD Akavia, D Pe'er, ... Proceedings of the National Academy of Sciences 108 (39), E771-E780, 2011 | 145 | 2011 |
Mild and Direct C–H Arylation of Quinoxalin-2 (1H)-ones with Aryldiazonium Salts under Metal-Free Conditions K Yin, R Zhang Synlett 29 (05), 597-602, 2018 | 45 | 2018 |
Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design ME Welsch, J Zhou, Y Gao, Y Yan, G Porter, G Agnihotri, Y Li, H Lu, ... ACS Medicinal Chemistry Letters 7 (12), 1124-1129, 2016 | 27 | 2016 |
Quinazolinone-based oncogenic-RAS-selective lethal compounds and their use BR Stockwell, M Welsch, WS Yang US Patent 9,695,133, 2017 | 26 | 2017 |
Small molecule that reverses dexamethasone resistance in T-cell acute lymphoblastic leukemia (T-ALL) AM Cantley, M Welsch, A Ambesi-Impiombato, M Sanchez-Martin, ... ACS Medicinal Chemistry Letters 5 (7), 754-759, 2014 | 17 | 2014 |
A green, scalable, one-minute synthesis of benzimidazoles V Elumalai, JH Hansen Synlett 31 (06), 547-552, 2020 | 13 | 2020 |
Multivalent RAS binding compounds BR Stockwell, M Welsch US Patent 9,926,293, 2018 | 13 | 2018 |
A metal-free approach for brønsted acid promoted C–H alkylation of heteroarenes with alkyl peroxides Y Zeng, B Qian, Y Li, H Bao Synthesis 50 (16), 3250-3256, 2018 | 11 | 2018 |
From bioactive pyrrolidino [3, 4-c] pyrrolidines to more bioactive pyrrolidino [3, 4-b] pyrrolidines via ring-opening/ring-closing promoted by sodium methoxide S Belveren, O Larranaga, S Poyraz, HA Dondas, M Ülger, E Şahin, ... Synthesis 51 (07), 1565-1577, 2019 | 8 | 2019 |
One-Pot Coupling–Cyclization–Alkylation Synthesis of 1, 2, 5-Trisubstituted 7-Azaindoles in a Consecutive Three-component Fashion T Lessing, TJJ Mueller Synlett 28 (14), 1743-1747, 2017 | 7 | 2017 |
Organocatalytic Gram-Scale Synthesis and Alkylation of Heteroaryl and Electron-Rich Aryl α-Substituted γ-Lactones M Bos, F Buttard, A Vallée, E Riguet Synthesis 51 (16), 3151-3159, 2019 | 6 | 2019 |
Catalyst-Free Synthesis of Aminals from Indole-Derived α, α-Dicyanoolefins HL Cui, Y Shi, HQ Deng, JJ Lei, XJ Xu, X Tian, J Qiao, L Zhou Synlett 30 (02), 167-172, 2019 | 6 | 2019 |
A Convenient One-pot Synthesis of Chromenyl Acrylates and Acrylonitriles D Lopes, M Costa, J Loucano, F Proenca Synlett 31 (13), 1298-1302, 2020 | 4 | 2020 |
A first-in-class ex vivo combination between cytokine-induced memory like (CIML) NK cells and a CD38 targeting antibody recruiting molecule (ARM) as a novel approach to target … L Rastelli, M Mohsin, AM Rossi, E Alvarez Sotomayor, L Iben, A Vaill, ... Journal of Clinical Oncology 38 (15_suppl), 8523-8523, 2020 | 4 | 2020 |
Diethylzinc-Mediated Metalloamination–Alkylation of N, N-Dimethylhydrazinoalkenes. Catalysis of C–Zn Alkylation Using Simple Cu (I) Salts K Mickelsen, S Zabawa, T Livinghouse Synlett 29 (02), 181-184, 2018 | 4 | 2018 |
A novel class of bifunctional immunotherapeutic that exploits a universal antibody binding terminus (Uabt) to recruit endogenous antibodies to cell expressing Cd38 demonstrate … A Bunin, K McGrath, AM Rossi, M Welsch, C Vidal, D Trinh, D Spiegel, ... Blood 134, 1820, 2019 | 3 | 2019 |