| Structure− activity relationships of polymyxin antibiotics T Velkov, PE Thompson, RL Nation, J Li Journal of medicinal chemistry 53 (5), 1898-1916, 2010 | 821 | 2010 |
| PI 3-kinase p110β: a new target for antithrombotic therapy SP Jackson, SM Schoenwaelder, I Goncalves, WS Nesbitt, CL Yap, ... Nature medicine 11 (5), 507-514, 2005 | 731 | 2005 |
| Pharmacology of polymyxins: new insights into an ‘old’class of antibiotics T Velkov, KD Roberts, RL Nation, PE Thompson, J Li Future microbiology 8 (6), 711-724, 2013 | 555 | 2013 |
| A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity ZZ Deris, J Akter, S Sivanesan, KD Roberts, PE Thompson, RL Nation, ... The Journal of antibiotics 67 (2), 147-151, 2014 | 264 | 2014 |
| The major human and mouse granzymes are structurally and functionally divergent D Kaiserman, CH Bird, J Sun, A Matthews, K Ung, JC Whisstock, ... The Journal of cell biology 175 (4), 619-630, 2006 | 236 | 2006 |
| Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis A Lourbakos, C Chinni, P Thompson, J Potempa, J Travis, EJ Mackie, ... FEBS letters 435 (1), 45-48, 1998 | 206 | 1998 |
| The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases DT Manallack, RA Hughes, PE Thompson Journal of medicinal chemistry 48 (10), 3449-3462, 2005 | 152 | 2005 |
| Antimicrobial activity and toxicity of the major lipopeptide components of polymyxin B and colistin: last-line antibiotics against multidrug-resistant Gram-negative bacteria KD Roberts, MAK Azad, J Wang, AS Horne, PE Thompson, RL Nation, ... ACS infectious diseases 1 (11), 568-575, 2015 | 150 | 2015 |
| The phytosulfokine (PSK) receptor is capable of guanylate cyclase activity and enabling cyclic GMP-dependent signaling in plants L Kwezi, O Ruzvidzo, JI Wheeler, K Govender, S Iacuone, PE Thompson, ... Journal of Biological Chemistry 286 (25), 22580-22588, 2011 | 150 | 2011 |
| The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism D Wootten, CA Reynolds, KJ Smith, JC Mobarec, C Koole, EE Savage, ... Cell 165 (7), 1632-1643, 2016 | 146 | 2016 |
| Probing the penetration of antimicrobial polymyxin lipopeptides into gram-negative bacteria ZZ Deris, JD Swarbrick, KD Roberts, MAK Azad, J Akter, AS Horne, ... Bioconjugate chemistry 25 (4), 750-760, 2014 | 140 | 2014 |
| Teaching ‘old’polymyxins new tricks: new-generation lipopeptides targeting gram-negative ‘superbugs’ T Velkov, KD Roberts, RL Nation, J Wang, PE Thompson, J Li ACS chemical biology 9 (5), 1172-1177, 2014 | 134 | 2014 |
| Identification and development of specific inhibitors for insulin‐regulated aminopeptidase as a new class of cognitive enhancers AL Albiston, S Diwakarla, RN Fernando, SJ Mountford, HR Yeatman, ... British journal of pharmacology 164 (1), 37-47, 2011 | 107 | 2011 |
| Pharmacokinetics of four different brands of colistimethate and formed colistin in rats H He, JC Li, RL Nation, J Jacob, G Chen, HJ Lee, BT Tsuji, PE Thompson, ... Journal of Antimicrobial Chemotherapy 68 (10), 2311-2317, 2013 | 98 | 2013 |
| Importance of the P4′ residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop J Sun, JC Whisstock, P Harriott, B Walker, A Novak, PE Thompson, ... Journal of Biological Chemistry 276 (18), 15177-15184, 2001 | 96 | 2001 |
| Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites BL Howard, KL Harvey, RJ Stewart, MF Azevedo, BS Crabb, IG Jennings, ... ACS chemical biology 10 (4), 1145-1154, 2015 | 94 | 2015 |
| RhoA Sustains Integrin αIIbβ3Adhesion Contacts under High Shear SM Schoenwaelder, SC Hughan, K Boniface, S Fernando, M Holdsworth, ... Journal of Biological Chemistry 277 (17), 14738-14746, 2002 | 90 | 2002 |
| Inhibition of phosphoinositide 3-kinase β SP Jackson, AD Robertson, V Kenche, P Thompson, H Prabaharan, ... US Patent 7,598,377, 2009 | 88 | 2009 |
| Homoanatoxin: a potent analogue of anatoxin-a S Wonnacott, KL Swanson, EX Albuquerque, NJS Huby, P Thompson, ... Biochemical pharmacology 43 (3), 419-423, 1992 | 87 | 1992 |
| Polymyxins: a new hope in combating Gram-negative superbugs? T Velkov, KD Roberts, PE Thompson, J Li Future medicinal chemistry 8 (10), 1017-1025, 2016 | 83 | 2016 |
