Removal of N-linked glycosylation enhances PD-L1 detection and predicts anti-PD-1/PD-L1 therapeutic efficacy HH Lee, YN Wang, W Xia, CH Chen, KM Rau, L Ye, Y Wei, CK Chou, ... Cancer cell 36 (2), 168-178. e4, 2019 | 287 | 2019 |
Nuclear trafficking of the epidermal growth factor receptor family membrane proteins YN Wang, H Yamaguchi, JM Hsu, MC Hung Oncogene 29 (28), 3997-4006, 2010 | 267 | 2010 |
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation JM Hsu, CT Chen, CK Chou, HP Kuo, LY Li, CY Lin, HJ Lee, YN Wang, ... Nature cell biology 13 (2), 174-181, 2011 | 261 | 2011 |
Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene … LY Hung, JT Tseng, YC Lee, W Xia, YN Wang, ML Wu, YH Chuang, ... Nucleic acids research 36 (13), 4337-4351, 2008 | 249 | 2008 |
Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells WC Huang, YJ Chen, LY Li, YL Wei, SC Hsu, SL Tsai, PC Chiu, ... Journal of Biological Chemistry 286 (23), 20558-20568, 2011 | 202 | 2011 |
Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family YN Wang, MC Hung Cell & bioscience 2, 1-10, 2012 | 175 | 2012 |
COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport YN Wang, H Wang, H Yamaguchi, HJ Lee, HH Lee, MC Hung Biochemical and biophysical research communications 399 (4), 498-504, 2010 | 175 | 2010 |
Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells Q Jin, LX Yuan, D Boulbes, JM Baek, YN Wang, D Gomez-Cabello, ... Breast Cancer Research 12, 1-15, 2010 | 165 | 2010 |
The translocon Sec61β localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus YN Wang, H Yamaguchi, L Huo, Y Du, HJ Lee, HH Lee, H Wang, JM Hsu, ... Journal of Biological Chemistry 285 (49), 38720-38729, 2010 | 143 | 2010 |
PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response HW Liao, JM Hsu, W Xia, HL Wang, YN Wang, WC Chang, ST Arold, ... The Journal of clinical investigation 125 (12), 4529-4543, 2015 | 140 | 2015 |
RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus L Huo, YN Wang, W Xia, SC Hsu, CC Lai, LY Li, WC Chang, Y Wang, ... Proceedings of the National Academy of Sciences 107 (37), 16125-16130, 2010 | 131 | 2010 |
The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis YN Wang, HH Lee, JL Hsu, D Yu, MC Hung Journal of biomedical science 27, 1-11, 2020 | 126 | 2020 |
Caspase-independent cell death is involved in the negative effect of egf receptor inhibitors on cisplatin in non–small cell lung cancer cells H Yamaguchi, JL Hsu, CT Chen, YN Wang, MC Hsu, SS Chang, Y Du, ... Clinical cancer research 19 (4), 845-854, 2013 | 124 | 2013 |
Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2 YN Wang, HH Lee, HJ Lee, Y Du, H Yamaguchi, MC Hung Journal of Biological Chemistry 287 (20), 16869-16879, 2012 | 95 | 2012 |
EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4 RH Chou, YN Wang, YH Hsieh, LY Li, W Xia, WC Chang, LC Chang, ... Developmental cell 30 (2), 224-237, 2014 | 89 | 2014 |
Induction of disease-associated keratin 16 gene expression by epidermal growth factor is regulated through cooperation of transcription factors Sp1 and c-Jun YN Wang, WC Chang Journal of Biological Chemistry 278 (46), 45848-45857, 2003 | 87 | 2003 |
ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression YJ Chen, YN Wang, WC Chang Journal of Biological Chemistry 282 (37), 27215-27228, 2007 | 86 | 2007 |
Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes LY Li, H Chen, YH Hsieh, YN Wang, HJ Chu, YH Chen, HY Chen, ... Cancer research 71 (12), 4269-4279, 2011 | 78 | 2011 |
Angiogenin/ribonuclease 5 is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer YN Wang, HH Lee, CK Chou, WH Yang, Y Wei, CT Chen, J Yao, JL Hsu, ... Cancer Cell 33 (4), 752-769. e8, 2018 | 75 | 2018 |
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers TH Huang, L Huo, YN Wang, W Xia, Y Wei, SS Chang, WC Chang, ... Cancer cell 23 (6), 796-810, 2013 | 71 | 2013 |