Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation SM Hurst, TS Wilkinson, RM McLoughlin, S Jones, S Horiuchi, ... Immunity 14 (6), 705-714, 2001 | 1069 | 2001 |
IL-6 regulates neutrophil trafficking during acute inflammation via STAT3 CA Fielding, RM McLoughlin, L McLeod, CS Colmont, M Najdovska, ... The journal of immunology 181 (3), 2189-2195, 2008 | 462 | 2008 |
IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation RM McLoughlin, BJ Jenkins, D Grail, AS Williams, CA Fielding, CR Parker, ... Proceedings of the National Academy of Sciences 102 (27), 9589-9594, 2005 | 436 | 2005 |
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4 EA McNeela, A Burke, DR Neill, C Baxter, VE Fernandes, D Ferreira, ... PLoS pathogens 6 (11), e1001191, 2010 | 420 | 2010 |
Interleukin-6 signaling drives fibrosis in unresolved inflammation CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, ... Immunity 40 (1), 40-50, 2014 | 379 | 2014 |
Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine PJ Ross, CE Sutton, S Higgins, AC Allen, K Walsh, A Misiak, EC Lavelle, ... PLoS pathogens 9 (4), e1003264, 2013 | 360 | 2013 |
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling BJ Jenkins, D Grail, T Nheu, M Najdovska, B Wang, P Waring, M Inglese, ... Nature medicine 11 (8), 845-852, 2005 | 358 | 2005 |
Interplay between IFN-γ and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation RM McLoughlin, J Witowski, RL Robson, TS Wilkinson, SM Hurst, ... The Journal of clinical investigation 112 (4), 598-607, 2003 | 353 | 2003 |
Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design AF Brown, JM Leech, TR Rogers, RM McLoughlin Frontiers in immunology 4, 507, 2014 | 316 | 2014 |
A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2 Q Wang, RM McLoughlin, BA Cobb, M Charrel-Dennis, KJ Zaleski, ... The Journal of experimental medicine 203 (13), 2853-2863, 2006 | 301 | 2006 |
Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma RM McLoughlin, KHG Mills Journal of Allergy and Clinical Immunology 127 (5), 1097-1107, 2011 | 274 | 2011 |
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells GW Jones, RM McLoughlin, VJ Hammond, CR Parker, JD Williams, ... The journal of immunology 184 (4), 2130-2139, 2010 | 236 | 2010 |
Nasal Colonisation by Staphylococcus aureus Depends upon Clumping Factor B Binding to the Squamous Epithelial Cell Envelope Protein Loricrin ME Mulcahy, JA Geoghegan, IR Monk, KM O'Keeffe, EJ Walsh, TJ Foster, ... PLoS pathogens 8 (12), e1003092, 2012 | 210 | 2012 |
Differential regulation of neutrophil-activating chemokines by IL-6 and its soluble receptor isoforms RM McLoughlin, SM Hurst, MA Nowell, DA Harris, S Horiuchi, LW Morgan, ... The Journal of Immunology 172 (9), 5676-5683, 2004 | 191 | 2004 |
The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens KA Lacey, JA Geoghegan, RM McLoughlin Pathogens 5 (1), 22, 2016 | 179 | 2016 |
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection AF Brown, AG Murphy, SJ Lalor, JM Leech, KM O’Keeffe, M Mac Aogáin, ... PLoS pathogens 11 (11), e1005226, 2015 | 173 | 2015 |
Staphylococcus aureus infection of mice expands a population of memory γδ T cells that are protective against subsequent infection AG Murphy, KM O’Keeffe, SJ Lalor, BM Maher, KHG Mills, RM McLoughlin The Journal of Immunology 192 (8), 3697-3708, 2014 | 164 | 2014 |
CD4+ T cells and CXC chemokines modulate the pathogenesis of Staphylococcus aureus wound infections RM McLoughlin, RM Solinga, J Rich, KJ Zaleski, JL Cocchiaro, A Risley, ... Proceedings of the National Academy of Sciences 103 (27), 10408-10413, 2006 | 143 | 2006 |
Host–bacterial crosstalk determines Staphylococcus aureus nasal colonization ME Mulcahy, RM McLoughlin Trends in microbiology 24 (11), 872-886, 2016 | 139 | 2016 |
Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis PJ Richards, MA Nowell, S Horiuchi, RM McLoughlin, CA Fielding, S Grau, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 132 | 2006 |