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Francis Willard
Francis Willard
在 lilly.com 的电子邮件经过验证
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G-protein signaling: back to the future
CR McCudden, MD Hains, RJ Kimple, DP Siderovski, FS Willard
Cellular and molecular life sciences 62, 551-577, 2005
7442005
The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
DP Siderovski, FS Willard
International journal of biological sciences 1 (2), 51, 2005
5732005
A seven-transmembrane RGS protein that modulates plant cell proliferation
JG Chen, FS Willard, J Huang, J Liang, SA Chasse, AM Jones, ...
Science 301 (5640), 1728-1731, 2003
3812003
Crystal structure of the human PRMT5: MEP50 complex
S Antonysamy, Z Bonday, RM Campbell, B Doyle, Z Druzina, T Gheyi, ...
Proceedings of the National Academy of Sciences 109 (44), 17960-17965, 2012
3762012
Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos
K Colombo, SW Grill, RJ Kimple, FS Willard, DP Siderovski, P Gönczy
Science 300 (5627), 1957-1961, 2003
3652003
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
FS Willard, JD Douros, MBN Gabe, AD Showalter, DB Wainscott, ...
JCI insight 5 (17), 2020
2522020
GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling
CA Johnston, JP Taylor, Y Gao, AJ Kimple, JC Grigston, JG Chen, ...
Proceedings of the National Academy of Sciences 104 (44), 17317-17322, 2007
2462007
Return of the GDI: the GoLoco motif in cell division
FS Willard, RJ Kimple, DP Siderovski
Annual review of biochemistry 73 (1), 925-951, 2004
2422004
RIC-8 is required for GPR-1/2-dependent Gα function during asymmetric division of C. elegans embryos
K Afshar, FS Willard, K Colombo, CA Johnston, CR McCudden, ...
Cell 119 (2), 219-230, 2004
2252004
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits
M Soundararajan, FS Willard, AJ Kimple, AP Turnbull, LJ Ball, GA Schoch, ...
Proceedings of the National Academy of Sciences 105 (17), 6457-6462, 2008
2232008
Rgs1 regulates multiple Gα subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism
H Liu, A Suresh, FS Willard, DP Siderovski, S Lu, NI Naqvi
The EMBO journal 26 (3), 690-700, 2007
1772007
Role of the p70 S6K pathway in regulating the actin cytoskeleton and cell migration
LA Berven, FS Willard, MF Crouch
Experimental cell research 296 (2), 183-195, 2004
1692004
Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets
KW Sloop, FS Willard, MB Brenner, J Ficorilli, K Valasek, AD Showalter, ...
Diabetes 59 (12), 3099-3107, 2010
1572010
Comment on "A G Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid"
CA Johnston, BR Temple, JG Chen, Y Gao, EN Moriyama, AM Jones, ...
Science 318 (5852), 914, 2007
1482007
Activation of the GLP-1 receptor by a non-peptidic agonist
P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ...
Nature 577 (7790), 432-436, 2020
1392020
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept
T Coskun, S Urva, WC Roell, H Qu, C Loghin, JS Moyers, LS O’Farrell, ...
Cell Metabolism 34 (9), 1234-1247. e9, 2022
1302022
Chronic olanzapine treatment causes differential expression of genes in frontal cortex of rats as revealed by DNA microarray technique
SH Fatemi, TJ Reutiman, TD Folsom, C Bell, L Nos, P Fried, DA Pearce, ...
Neuropsychopharmacology 31 (9), 1888-1899, 2006
1172006
MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit
FS Willard, MF Crouch
Cellular signalling 13 (9), 653-664, 2001
1142001
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist
T Kawai, B Sun, H Yoshino, D Feng, Y Suzuki, M Fukazawa, S Nagao, ...
Proceedings of the National Academy of Sciences 117 (47), 29959-29967, 2020
1062020
Differential activation and modulation of the glucagon-like peptide-1 receptor by small molecule ligands
D Wootten, EE Savage, FS Willard, AB Bueno, KW Sloop, A Christopoulos, ...
Molecular pharmacology 83 (4), 822-834, 2013
1052013
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