G-protein signaling: back to the future CR McCudden, MD Hains, RJ Kimple, DP Siderovski, FS Willard Cellular and molecular life sciences 62, 551-577, 2005 | 744 | 2005 |
The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits DP Siderovski, FS Willard International journal of biological sciences 1 (2), 51, 2005 | 573 | 2005 |
A seven-transmembrane RGS protein that modulates plant cell proliferation JG Chen, FS Willard, J Huang, J Liang, SA Chasse, AM Jones, ... Science 301 (5640), 1728-1731, 2003 | 381 | 2003 |
Crystal structure of the human PRMT5: MEP50 complex S Antonysamy, Z Bonday, RM Campbell, B Doyle, Z Druzina, T Gheyi, ... Proceedings of the National Academy of Sciences 109 (44), 17960-17965, 2012 | 376 | 2012 |
Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos K Colombo, SW Grill, RJ Kimple, FS Willard, DP Siderovski, P Gönczy Science 300 (5627), 1957-1961, 2003 | 365 | 2003 |
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist FS Willard, JD Douros, MBN Gabe, AD Showalter, DB Wainscott, ... JCI insight 5 (17), 2020 | 252 | 2020 |
GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling CA Johnston, JP Taylor, Y Gao, AJ Kimple, JC Grigston, JG Chen, ... Proceedings of the National Academy of Sciences 104 (44), 17317-17322, 2007 | 246 | 2007 |
Return of the GDI: the GoLoco motif in cell division FS Willard, RJ Kimple, DP Siderovski Annual review of biochemistry 73 (1), 925-951, 2004 | 242 | 2004 |
RIC-8 is required for GPR-1/2-dependent Gα function during asymmetric division of C. elegans embryos K Afshar, FS Willard, K Colombo, CA Johnston, CR McCudden, ... Cell 119 (2), 219-230, 2004 | 225 | 2004 |
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits M Soundararajan, FS Willard, AJ Kimple, AP Turnbull, LJ Ball, GA Schoch, ... Proceedings of the National Academy of Sciences 105 (17), 6457-6462, 2008 | 223 | 2008 |
Rgs1 regulates multiple Gα subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism H Liu, A Suresh, FS Willard, DP Siderovski, S Lu, NI Naqvi The EMBO journal 26 (3), 690-700, 2007 | 177 | 2007 |
Role of the p70 S6K pathway in regulating the actin cytoskeleton and cell migration LA Berven, FS Willard, MF Crouch Experimental cell research 296 (2), 183-195, 2004 | 169 | 2004 |
Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets KW Sloop, FS Willard, MB Brenner, J Ficorilli, K Valasek, AD Showalter, ... Diabetes 59 (12), 3099-3107, 2010 | 157 | 2010 |
Comment on "A G Protein–Coupled Receptor Is a Plasma Membrane Receptor for the Plant Hormone Abscisic Acid" CA Johnston, BR Temple, JG Chen, Y Gao, EN Moriyama, AM Jones, ... Science 318 (5852), 914, 2007 | 148 | 2007 |
Activation of the GLP-1 receptor by a non-peptidic agonist P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ... Nature 577 (7790), 432-436, 2020 | 139 | 2020 |
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept T Coskun, S Urva, WC Roell, H Qu, C Loghin, JS Moyers, LS O’Farrell, ... Cell Metabolism 34 (9), 1234-1247. e9, 2022 | 130 | 2022 |
Chronic olanzapine treatment causes differential expression of genes in frontal cortex of rats as revealed by DNA microarray technique SH Fatemi, TJ Reutiman, TD Folsom, C Bell, L Nos, P Fried, DA Pearce, ... Neuropsychopharmacology 31 (9), 1888-1899, 2006 | 117 | 2006 |
MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit FS Willard, MF Crouch Cellular signalling 13 (9), 653-664, 2001 | 114 | 2001 |
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist T Kawai, B Sun, H Yoshino, D Feng, Y Suzuki, M Fukazawa, S Nagao, ... Proceedings of the National Academy of Sciences 117 (47), 29959-29967, 2020 | 106 | 2020 |
Differential activation and modulation of the glucagon-like peptide-1 receptor by small molecule ligands D Wootten, EE Savage, FS Willard, AB Bueno, KW Sloop, A Christopoulos, ... Molecular pharmacology 83 (4), 822-834, 2013 | 105 | 2013 |