Structures of influenza A virus RNA polymerase offer insight into viral genome replication H Fan, AP Walker, L Carrique, JR Keown, I Serna Martin, D Karia, ... Nature 573 (7773), 287-290, 2019 | 170 | 2019 |
Host ANP32A mediates the assembly of the influenza virus replicase L Carrique, H Fan, AP Walker, JR Keown, J Sharps, E Staller, WS Barclay, ... Nature 587 (7835), 638-643, 2020 | 94 | 2020 |
Transcription–translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits H Fan, AB Conn, PB Williams, S Diggs, J Hahm, HB Gamper, YM Hou, ... Nucleic Acids Research 45 (19), 11043–11055, 2017 | 84 | 2017 |
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification HT Baddock, S Brolih, Y Yosaatmadja, M Ratnaweera, M Bielinski, ... Nucleic acids research 50 (3), 1484-1500, 2022 | 54 | 2022 |
Soil microbial abundances and enzyme activities in different rhizospheres in an integrated vertical flow constructed wetland Y Ge, C Zhang, Y Jiang, C Yue, Q Jiang, H Min, H Fan, Q Zeng, J Chang CLEAN–Soil, Air, Water 39 (3), 206-211, 2011 | 50 | 2011 |
The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme AP Walker, H Fan, JR Keown, ML Knight, JM Grimes, E Fodor Nucleic acids research 49 (22), 13019-13030, 2021 | 48* | 2021 |
Structural and functional analysis of BipA, a regulator of virulence in enteropathogenic Escherichia coli H Fan, J Hahm, S Diggs, JJP Perry, G Blaha Journal of Biological Chemistry 290 (34), 20856-20864, 2015 | 37 | 2015 |
Crystal structure of Arabidopsis Deg2 protein reveals an internal PDZ ligand locking the hexameric resting state R Sun, H Fan, F Gao, Y Lin, L Zhang, W Gong, L Liu Journal of Biological Chemistry 287 (44), 37564-37569, 2012 | 36 | 2012 |
Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases AP Walker, H Fan, JR Keown, V Margitich, JM Grimes, E Fodor, ... bioRxiv, 2020 | 20 | 2020 |
The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases W Sun, F Gao, H Fan, X Shan, R Sun, L Liu, W Gong Acta Crystallographica Section D: Biological Crystallography 69 (5), 830-837, 2013 | 19 | 2013 |
The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome F Wang, CM Sheppard, B Mistry, E Staller, WS Barclay, JM Grimes, ... Nucleic Acids Research 50 (10), 5713-5725, 2022 | 18 | 2022 |
Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies JR Keown, Z Zhu, L Carrique, H Fan, AP Walker, I Serna Martin, E Pardon, ... Nature Communications 13 (1), 251, 2022 | 16 | 2022 |
Structure of an H3N2 influenza virus nucleoprotein ML Knight, H Fan, DLV Bauer, JM Grimes, E Fodor, JR Keown Acta Crystallographica Section F: Structural Biology Communications 77 (7 …, 2021 | 16 | 2021 |
The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a H Veler, H Fan, JR Keown, J Sharps, M Fournier, JM Grimes, E Fodor Journal of Virology 96 (5), e01979-21, 2022 | 14 | 2022 |
Defining the minimal components of the influenza A virus replication machinery via an in vitro reconstitution system Z Zhu, H Fan, E Fodor PLoS biology 21 (11), e3002370, 2023 | 5 | 2023 |
Expression, purification, crystallization and preliminary X-ray diffraction analysis of Arabidopsis thaliana Deg8 X Shan, W Sun, H Fan, M Jia, F Gao, W Gong Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 3 | 2013 |
Expression, purification, crystallization and preliminary X-ray diffraction analysis of Deg5 from Arabidopsis thaliana H Fan, W Sun, Z Sun, F Gao, W Gong Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 3 | 2012 |
Dimerisation of the influenza virus RNA polymerase during viral genome replication A Walker, H Fan, L Carrique, J Keown, D Bauer, J Grimes, E Fodor Access Microbiology 1 (1A), 292, 2019 | 2 | 2019 |
Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation E Staller, L Carrique, OC Swann, H Fan, JR Keown, CM Sheppard, ... Nature communications 15 (1), 4123, 2024 | 1 | 2024 |
Identification of guanylyltransferase activity in the SARS-CoV-2 RNA polymerase (preprint) AP Walker, H Fan, JR Keown, J Grimes, E Fodor | | 2021 |