| Local protein kinase A action proceeds through intact holoenzymes FD Smith, JL Esseltine, PJ Nygren, D Veesler, DP Byrne, M Vonderach, ... Science 356 (6344), 1288-1293, 2017 | 199 | 2017 |
| Strong anion exchange‐mediated phosphoproteomics reveals extensive human non‐canonical phosphorylation G Hardman, S Perkins, PJ Brownridge, CJ Clarke, DP Byrne, ... The EMBO journal 38 (21), e100847, 2019 | 150 | 2019 |
| Evaluating caveolin interactions: do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif? DP Byrne, C Dart, DJ Rigden Public Library of Science 7 (9), e44879, 2012 | 135 | 2012 |
| A single sulfatase is required to access colonic mucin by a gut bacterium AS Luis, C Jin, GV Pereira, RWP Glowacki, SR Gugel, S Singh, DP Byrne, ... Nature 598 (7880), 332-337, 2021 | 113 | 2021 |
| HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis JW Smalley, DP Byrne, AJ Birss, H Wojtowicz, A Sroka, J Potempa, ... PLoS One 6 (2), e17182, 2011 | 95 | 2011 |
| The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner FP Bailey, DP Byrne, K Oruganty, CE Eyers, CJ Novotny, KM Shokat, ... The Biochemical journal 467 (1), 47, 2015 | 92 | 2015 |
| Pseudokinases: update on their functions and evaluation as new drug targets DP Byrne, DM Foulkes, PA Eyers Future medicinal chemistry 9 (2), 245-265, 2017 | 82 | 2017 |
| Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity DP Byrne, S Shrestha, M Galler, M Cao, LA Daly, AE Campbell, CE Eyers, ... Science signaling 13 (639), eaax2713, 2020 | 75 | 2020 |
| Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells DM Foulkes, DP Byrne, W Yeung, S Shrestha, FP Bailey, S Ferries, ... Science signaling 11 (549), eaat7951, 2018 | 75 | 2018 |
| Evidence of mutualism between two periodontal pathogens: co‐operative haem acquisition by the HmuY haemophore of Porphyromonas gingivalis and the cysteine protease … DP Byrne, J Potempa, T Olczak, JW Smalley Molecular oral microbiology 28 (3), 219-229, 2013 | 69 | 2013 |
| BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL G Greaves, M Milani, M Butterworth, RJ Carter, DP Byrne, PA Eyers, ... Cell Death & Differentiation 26 (6), 1037-1047, 2019 | 67 | 2019 |
| Metabolic control of BRISC–SHMT2 assembly regulates immune signalling M Walden, L Tian, RL Ross, UM Sykora, DP Byrne, EL Hesketh, ... Nature 570 (7760), 194-199, 2019 | 61 | 2019 |
| cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility–mass spectrometry DP Byrne, M Vonderach, S Ferries, PJ Brownridge, CE Eyers, PA Eyers Biochemical Journal 473 (19), 3159-3175, 2016 | 60 | 2016 |
| Covalent Aurora A regulation by the metabolic integrator coenzyme A Y Tsuchiya, DP Byrne, SG Burgess, J Bormann, J Baković, Y Huang, ... Redox biology 28, 101318, 2020 | 56 | 2020 |
| KinView: a visual comparative sequence analysis tool for integrated kinome research DI McSkimming, S Dastgheib, TR Baffi, DP Byrne, S Ferries, ST Scott, ... Molecular bioSystems 12 (12), 3651-3665, 2016 | 47 | 2016 |
| DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis M Milani, DP Byrne, G Greaves, M Butterworth, GM Cohen, PA Eyers, ... Cell death & disease 8 (1), e2552-e2552, 2018 | 45 | 2018 |
| Role of the cysteine protease interpain A of Prevotella intermedia in breakdown and release of haem from haemoglobin DP Byrne, K Wawrzonek, A Jaworska, AJ Birss, J Potempa, JW Smalley Biochemical Journal 425 (1), 257-264, 2010 | 40 | 2010 |
| Hydrophobic core variations provide a structural framework for tyrosine kinase evolution and functional specialization S Mohanty, K Oruganty, A Kwon, DP Byrne, S Ferries, Z Ruan, LE Hanold, ... PLoS genetics 12 (2), e1005885, 2016 | 39 | 2016 |
| Cataloguing the dead: breathing new life into pseudokinase research S Shrestha, DP Byrne, JA Harris, N Kannan, PA Eyers The FEBS Journal 287 (19), 4150-4169, 2020 | 36 | 2020 |
| Going for broke: targeting the human cancer pseudokinome FP Bailey, DP Byrne, D McSkimming, N Kannan, PA Eyers Biochemical journal 465 (2), 195-211, 2015 | 35 | 2015 |
