| High-resolution crystal structure of the human CB1 cannabinoid receptor Z Shao, J Yin, K Chapman, M Grzemska, L Clark, J Wang, ... Nature 540 (7634), 602-606, 2016 | 423 | 2016 |
| Structure of an allosteric modulator bound to the CB1 cannabinoid receptor Z Shao, W Yan, K Chapman, K Ramesh, AJ Ferrell, J Yin, X Wang, Q Xu, ... Nature chemical biology 15 (12), 1199-1205, 2019 | 153 | 2019 |
| Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature Structural & Molecular Biology 23 (4), 293-299, 2016 | 145 | 2016 |
| Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes P Xiao, W Yan, L Gou, YN Zhong, L Kong, C Wu, X Wen, Y Yuan, S Cao, ... Cell 184 (4), 943-956. e18, 2021 | 100 | 2021 |
| Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition Y Yuan, G Jia, C Wu, W Wang, L Cheng, Q Li, Z Li, K Luo, S Yang, W Yan, ... Cell research 31 (12), 1263-1274, 2021 | 56 | 2021 |
| Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate Z Shao, W Yan, J Peng, X Zuo, Y Zou, F Li, D Gong, R Ma, J Wu, Y Shi, ... Nucleic acids research 42 (1), 509-525, 2014 | 56 | 2014 |
| Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1 X Yang, X Wang, Z Xu, C Wu, Y Zhou, Y Wang, G Lin, K Li, M Wu, A Xia, ... Nature Chemical Biology 18 (8), 831-840, 2022 | 50 | 2022 |
| Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model W Yang, X Liu, C Song, S Ji, J Yang, Y Liu, J You, J Zhang, S Huang, ... European Journal of Medicinal Chemistry 209, 112842, 2021 | 43 | 2021 |
| Crystal structure of the human NK1 tachykinin receptor J Yin, K Chapman, LD Clark, Z Shao, D Borek, Q Xu, J Wang, ... Proceedings of the National Academy of Sciences 115 (52), 13264-13269, 2018 | 41 | 2018 |
| Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode W Yan, L Cheng, W Wang, C Wu, X Yang, X Du, L Ma, S Qi, Y Wei, Z Lu, ... Nature Communications 11 (1), 5287, 2020 | 35 | 2020 |
| Structural basis of γH2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathway W Yan, Z Shao, F Li, L Niu, Y Shi, M Teng, X Li FEBS letters 585 (24), 3874-3879, 2011 | 33 | 2011 |
| Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3–Gi signaling complexes C Zhao, L Cheng, W Wang, H Wang, Y Luo, Y Feng, X Wang, H Fu, Y Cai, ... Cell research 32 (2), 218-221, 2022 | 32 | 2022 |
| Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4 Y Zou, Z Shao, J Peng, F Li, D Gong, C Wang, X Zuo, Z Zhang, J Wu, ... FEBS letters 588 (17), 2911-2920, 2014 | 29 | 2014 |
| Molecular mechanism of agonism and inverse agonism in ghrelin receptor J Qin, Y Cai, Z Xu, Q Ming, SY Ji, C Wu, H Zhang, C Mao, DD Shen, ... Nature Communications 13 (1), 300, 2022 | 25 | 2022 |
| Ligand recognition and biased agonism of the D1 dopamine receptor X Teng, S Chen, Y Nie, P Xiao, X Yu, Z Shao, S Zheng Nature communications 13 (1), 3186, 2022 | 23 | 2022 |
| Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure Z Shao, F Li, SMH Sy, W Yan, Z Zhang, D Gong, B Wen, MSY Huen, ... Journal of structural biology 177 (2), 459-468, 2012 | 20 | 2012 |
| Mechanism of activation and biased signaling in complement receptor C5aR1 Y Feng, C Zhao, Y Deng, H Wang, L Ma, S Liu, X Tian, B Wang, Y Bin, ... Cell Research 33 (4), 312-324, 2023 | 19 | 2023 |
| Non-classical ferroptosis inhibition by a small molecule targeting PHB2 W Yang, B Mu, J You, C Tian, H Bin, Z Xu, L Zhang, R Ma, M Wu, G Zhang, ... Nature Communications 13 (1), 7473, 2022 | 17 | 2022 |
| Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine J Zhao, H Fu, J Yu, W Hong, X Tian, J Qi, S Sun, C Zhao, C Wu, Z Xu, ... Nature Communications 14 (1), 962, 2023 | 16 | 2023 |
| Allosteric modulation of G protein-coupled receptor signaling S Shen, C Zhao, C Wu, S Sun, Z Li, W Yan, Z Shao Frontiers in Endocrinology 14, 1137604, 2023 | 15 | 2023 |
