Picomolar amyloid-β positively modulates synaptic plasticity and memory in hippocampus D Puzzo, L Privitera, E Leznik, M Fa, A Staniszewski, A Palmeri, O Arancio Journal of Neuroscience 28 (53), 14537-14545, 2008 | 923 | 2008 |
RAGE potentiates Aβ‐induced perturbation of neuronal function in transgenic mice O Arancio, HP Zhang, X Chen, C Lin, F Trinchese, D Puzzo, S Liu, ... The EMBO journal 23 (20), 4096-4105, 2004 | 427 | 2004 |
Endogenous amyloid‐β is necessary for hippocampal synaptic plasticity and memory D Puzzo, L Privitera, M Fa', A Staniszewski, G Hashimoto, F Aziz, ... Annals of neurology 69 (5), 819-830, 2011 | 381 | 2011 |
Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-β load in an Alzheimer's disease mouse model D Puzzo, A Staniszewski, SX Deng, L Privitera, E Leznik, S Liu, H Zhang, ... Journal of Neuroscience 29 (25), 8075-8086, 2009 | 336 | 2009 |
Amyloid-β peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity D Puzzo, O Vitolo, F Trinchese, JP Jacob, A Palmeri, O Arancio Journal of Neuroscience 25 (29), 6887-6897, 2005 | 306 | 2005 |
Extracellular tau oligomers produce an immediate impairment of LTP and memory M Fá, D Puzzo, R Piacentini, A Staniszewski, H Zhang, MA Baltrons, ... Scientific reports 6 (1), 19393, 2016 | 277 | 2016 |
Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines D Puzzo, L Lee, A Palmeri, G Calabrese, O Arancio Biochemical pharmacology 88 (4), 450-467, 2014 | 235 | 2014 |
Rodent models for Alzheimer’s disease drug discovery D Puzzo, W Gulisano, A Palmeri, O Arancio Expert opinion on drug discovery 10 (7), 703-711, 2015 | 232 | 2015 |
A GluR1-cGKII interaction regulates AMPA receptor trafficking Y Serulle, S Zhang, I Ninan, D Puzzo, M McCarthy, L Khatri, O Arancio, ... Neuron 56 (4), 670-688, 2007 | 204 | 2007 |
Amyloid-β peptide: Dr. Jekyll or Mr. Hyde? D Puzzo, O Arancio Journal of Alzheimer's Disease 33 (s1), S111-S120, 2013 | 189 | 2013 |
LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent D Puzzo, R Piacentini, M Fa, W Gulisano, DD Li Puma, A Staniszewski, ... Elife 6, e26991, 2017 | 153 | 2017 |
The keystone of Alzheimer pathogenesis might be sought in Aβ physiology D Puzzo, W Gulisano, O Arancio, A Palmeri Neuroscience 307, 26-36, 2015 | 153 | 2015 |
Role of amyloid-β and tau proteins in Alzheimer’s disease: confuting the amyloid cascade W Gulisano, D Maugeri, MA Baltrons, M Fà, A Amato, A Palmeri, ... Journal of Alzheimer's Disease 64 (s1), S611-S631, 2018 | 150 | 2018 |
Synaptic therapy in Alzheimer's disease: a CREB-centric approach AF Teich, RE Nicholls, D Puzzo, J Fiorito, R Purgatorio, O Arancio Neurotherapeutics 12 (1), 29-41, 2015 | 147 | 2015 |
Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory D Puzzo, L Privitera, A Palmeri Neurobiology of aging 33 (7), 1484. e15-1484. e24, 2012 | 132 | 2012 |
Intracellular accumulation of amyloid-β (Aβ) protein plays a major role in Aβ-induced alterations of glutamatergic synaptic transmission and plasticity C Ripoli, S Cocco, DDL Puma, R Piacentini, A Mastrodonato, F Scala, ... Journal of Neuroscience 34 (38), 12893-12903, 2014 | 130 | 2014 |
A key role for TGF-β1 in hippocampal synaptic plasticity and memory F Caraci, W Gulisano, CA Guida, AAR Impellizzeri, F Drago, D Puzzo, ... Scientific reports 5 (1), 11252, 2015 | 120 | 2015 |
Improved long-term memory via enhancing cGMP-PKG signaling requires cAMP-PKA signaling E Bollen, D Puzzo, K Rutten, L Privitera, J De Vry, T Vanmierlo, G Kenis, ... Neuropsychopharmacology 39 (11), 2497-2505, 2014 | 117 | 2014 |
Role of phosphodiesterase 5 in synaptic plasticity and memory D Puzzo, S Sapienza, O Arancio, A Palmeri Neuropsychiatric disease and treatment 4 (2), 371-387, 2008 | 115 | 2008 |
Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice D Puzzo, C Loreto, S Giunta, G Musumeci, G Frasca, MV Podda, ... Neurobiology of aging 35 (3), 520-531, 2014 | 89 | 2014 |