The unfolded protein response: integrating stress signals through the stress sensor IRE1α C Hetz, F Martinon, D Rodriguez, LH Glimcher Physiological reviews 91 (4), 1219-1243, 2011 | 669 | 2011 |
RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3 CP Dillon, R Weinlich, DA Rodriguez, JG Cripps, G Quarato, P Gurung, ... Cell 157 (5), 1189-1202, 2014 | 569 | 2014 |
Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis DA Rodriguez, R Weinlich, S Brown, C Guy, P Fitzgerald, CP Dillon, ... Cell Death & Differentiation 23 (1), 76-88, 2016 | 355 | 2016 |
RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus S Nogusa, RJ Thapa, CP Dillon, S Liedmann, TH Oguin, JP Ingram, ... Cell host & microbe 20 (1), 13-24, 2016 | 351 | 2016 |
The autophagy machinery controls cell death switching between apoptosis and necroptosis ML Goodall, BE Fitzwalter, S Zahedi, M Wu, D Rodriguez, ... Developmental cell 37 (4), 337-349, 2016 | 298 | 2016 |
The pseudokinase MLKL and the kinase RIPK3 have distinct roles in autoimmune disease caused by loss of death-receptor-induced apoptosis S Alvarez-Diaz, CP Dillon, N Lalaoui, MC Tanzer, DA Rodriguez, A Lin, ... Immunity 45 (3), 513-526, 2016 | 217 | 2016 |
Sequential engagement of distinct MLKL phosphatidylinositol-binding sites executes necroptosis G Quarato, CS Guy, CR Grace, F Llambi, A Nourse, DA Rodriguez, ... Molecular cell 61 (4), 589-601, 2016 | 216 | 2016 |
Integrating stress signals at the endoplasmic reticulum: the BCL-2 protein family rheostat D Rodriguez, D Rojas-Rivera, C Hetz Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (4), 564-574, 2011 | 199 | 2011 |
Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription JG Fernández, DA Rodríguez, M Valenzuela, C Calderon, U Urzúa, ... Molecular cancer 13, 1-15, 2014 | 169 | 2014 |
Protective roles for caspase-8 and cFLIP in adult homeostasis R Weinlich, A Oberst, CP Dillon, LJ Janke, S Milasta, JR Lukens, ... Cell reports 5 (2), 340-348, 2013 | 167 | 2013 |
Casein kinase 2 (CK2) increases survivin expression via enhanced β-catenin–T cell factor/lymphoid enhancer binding factor-dependent transcription JC Tapia, VA Torres, DA Rodriguez, L Leyton, AFG Quest Proceedings of the National Academy of Sciences 103 (41), 15079-15084, 2006 | 167 | 2006 |
Interactome screening identifies the ER luminal chaperone Hsp47 as a regulator of the unfolded protein response transducer IRE1α D Sepulveda, D Rojas-Rivera, DA Rodríguez, J Groenendyk, A Köhler, ... Molecular cell 69 (2), 238-252. e7, 2018 | 157 | 2018 |
Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin VA Torres, JC Tapia, DA Rodríguez, M Párraga, P Lisboa, M Montoya, ... Journal of cell science 119 (9), 1812-1823, 2006 | 149 | 2006 |
E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced β-catenin-Tcf/Lef-dependent transcription VA Torres, JC Tapia, DA Rodriguez, A Lladser, C Arredondo, L Leyton, ... Molecular and cellular biology 27 (21), 7703-7717, 2007 | 147 | 2007 |
BH3‐only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α DA Rodriguez, S Zamorano, F Lisbona, D Rojas‐Rivera, H Urra, ... The EMBO journal 31 (10), 2322-2335, 2012 | 130 | 2012 |
TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis D Rojas-Rivera, R Armisén, A Colombo, G Martinez, AL Eguiguren, ... Cell Death & Differentiation 19 (6), 1013-1026, 2012 | 92 | 2012 |
The caveolin-1 connection to cell death and survival A FG Quest, L Lobos-Gonzalez, S Nunez, C Sanhueza, JG Fernández, ... Current molecular medicine 13 (2), 266-281, 2013 | 91 | 2013 |
Caveolin-1–mediated Suppression of Cyclooxygenase-2 via a β-catenin-Tcf/Lef–dependent Transcriptional Mechanism Reduced Prostaglandin E2 Production and … DA Rodriguez, JC Tapia, JG Fernandez, VA Torres, N Munoz, ... Molecular biology of the cell 20 (8), 2297-2310, 2009 | 91 | 2009 |
Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells DA Rodriguez, C Moncada, MT Núñez, S Lavandero, BC Ponnappa, ... Alcohol 33 (1), 9-15, 2004 | 47 | 2004 |
Protein kinase CK2 promotes cancer cell viability via up‐regulation of cyclooxygenase‐2 expression and enhanced prostaglandin E2 production R Yefi, DP Ponce, I Niechi, E Silva, P Cabello, DA Rodriguez, K Marcelain, ... Journal of cellular biochemistry 112 (11), 3167-3175, 2011 | 33 | 2011 |