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Jeffrey C Rathmell
Jeffrey C Rathmell
Cornelius Vanderbilt Professor of Immunobiology, Vanderbilt Center for Immunobiology
在 vanderbilt.edu 的电子邮件经过验证
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引用次数
引用次数
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13276*2021
A guide to immunometabolism for immunologists
LAJ O'Neill, RJ Kishton, J Rathmell
Nature reviews immunology 16 (9), 553-565, 2016
25772016
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
RD Michalek, VA Gerriets, SR Jacobs, AN Macintyre, NJ MacIver, ...
The Journal of immunology 186 (6), 3299-3303, 2011
20962011
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
T Lindsten, AJ Ross, A King, WX Zong, JC Rathmell, HA Shiels, E Ulrich, ...
Molecular cell 6 (6), 1389-1399, 2000
18542000
The CD28 signaling pathway regulates glucose metabolism
KA Frauwirth, JL Riley, MH Harris, RV Parry, JC Rathmell, DR Plas, ...
Immunity 16 (6), 769-777, 2002
16422002
Metabolic regulation of T lymphocytes
NJ MacIver, RD Michalek, JC Rathmell
Annual review of immunology 31, 259-283, 2013
13032013
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
12592015
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function
AN Macintyre, VA Gerriets, AG Nichols, RD Michalek, MC Rudolph, ...
Cell metabolism 20 (1), 61-72, 2014
10952014
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
SR Jacobs, CE Herman, NJ MacIver, JA Wofford, HL Wieman, ...
The Journal of Immunology 180 (7), 4476-4486, 2008
9132008
Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype
AJ Freemerman, AR Johnson, GN Sacks, JJ Milner, EL Kirk, MA Troester, ...
Journal of Biological Chemistry 289 (11), 7884-7896, 2014
8722014
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival
JC Rathmell, CJ Fox, DR Plas, PS Hammerman, RM Cinalli, ...
Molecular and cellular biology 23 (20), 7315-7328, 2003
7102003
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking
HL Wieman, JA Wofford, JC Rathmell
Molecular biology of the cell 18 (4), 1437-1446, 2007
6882007
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ...
The Journal of clinical investigation 125 (1), 194-207, 2015
6772015
Pathways of apoptosis in lymphocyte development, homeostasis, and disease
JC Rathmell, CB Thompson
Cell 109 (2), S97-S107, 2002
6762002
Growth factors can influence cell growth and survival through effects on glucose metabolism
MG Vander Heiden, DR Plas, JC Rathmell, CJ Fox, MH Harris, ...
Molecular and cellular biology 21 (17), 5899-5912, 2001
6682001
Amino acids rather than glucose account for the majority of cell mass in proliferating mammalian cells
AM Hosios, VC Hecht, LV Danai, MO Johnson, JC Rathmell, ...
Developmental cell 36 (5), 540-549, 2016
6332016
Cell-programmed nutrient partitioning in the tumour microenvironment
BI Reinfeld, MZ Madden, MM Wolf, A Chytil, JE Bader, AR Patterson, ...
Nature 593 (7858), 282-288, 2021
6212021
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells
JC Rathmell, MP Cooke, WY Ho, J Grein, SE Townsend, MM Davis, ...
Nature 376 (6536), 181-184, 1995
6011995
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
NJ MacIver, SR Jacobs, HL Wieman, JA Wofford, JL Coloff, JC Rathmell
Journal of Leucocyte Biology 84 (4), 949-957, 2008
5842008
IL-7 enhances the survival and maintains the size of naive T cells
JC Rathmell, EA Farkash, W Gao, CB Thompson
The Journal of Immunology 167 (12), 6869-6876, 2001
5812001
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