Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 (7359), 214-219, 2011 | 2996 | 2011 |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ... Nature genetics 45 (11), 1353-1360, 2013 | 1348 | 2013 |
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 924 | 2019 |
Class II HLA interactions modulate genetic risk for multiple sclerosis Nature genetics 47 (10), 1107-1113, 2015 | 401 | 2015 |
VEGF receptor‐2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis T Matsumoto, S Bohman, J Dixelius, T Berge, A Dimberg, P Magnusson, ... The EMBO journal 24 (13), 2342-2353, 2005 | 388 | 2005 |
Features of autoimmune hepatitis in primary sclerosing cholangitis: an evaluation of 114 primary sclerosing cholangitis patients according to a scoring system for the diagnosis … KM Boberg, O Fausa, T Haaland, E Holter, OJ Mellbye, A Spurkland, ... Hepatology 23 (6), 1369-1376, 1996 | 259 | 1996 |
VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd Z Sun, X Li, S Massena, S Kutschera, N Padhan, L Gualandi, ... Journal of Experimental Medicine 209 (7), 1363-1377, 2012 | 244 | 2012 |
K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location J Breivik, GI Meling, A Spurkland, TO Rognum, G Gaudernack British journal of cancer 69 (2), 367-371, 1994 | 193 | 1994 |
CTLA4 promoter and exon 1 dimorphisms in multiple sclerosiso H Flinstad Harbo, E Gulowsen Celius, F Vartdal, A Spurkland Tissue Antigens 53 (1), 106-110, 1999 | 189 | 1999 |
HLA-DR and-DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7 A Spurkland, LM Sollid, I Polanco, F Vartdal, E Thorsby Human immunology 35 (3), 188-192, 1992 | 181 | 1992 |
Distribution of HLA‐DRB1,‐DQA1 and‐DQB1 alleles and DQA1‐DQB1 genotypes among Norwegian patients with insulin‐dependent diabetes mellitus KS Rønningen, A Spurkland, T Iwe, F Vartdal, E Thorsby Tissue Antigens 37 (3), 105-111, 1991 | 181 | 1991 |
Genes in the HLA class I region may contribute to the HLA class II‐associated genetic susceptibility to multiple sclerosis HF Harbo, BA Lie, S Sawcer, EG Celius, KZ Dai, A Oturai, J Hillert, ... Tissue antigens 63 (3), 237-247, 2004 | 175 | 2004 |
Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA‐DQ (α1* 0501,(β1* 02) or the HLA‐DQ (α1* 03,(β1* 0302) heterodimers A Spurkland, G Ingvarsson, ES Falk, I Knutsen, LM Sollid, E Thorsby Tissue Antigens 49 (1), 29-34, 1997 | 174 | 1997 |
HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis A Spurkland, KS Rønningen, B Vandvik, E Thorsby, F Vartdal Human immunology 30 (1), 69-75, 1991 | 174 | 1991 |
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations A Spurkland, S Saarinen, KM Boberg, S Mitchell, U Broome, L Caballeria, ... Tissue antigens 53 (5), 459-469, 1999 | 173 | 1999 |
Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls SE Baranzini, P Khankhanian, NA Patsopoulos, M Li, J Stankovich, ... The American Journal of Human Genetics 92 (6), 854-865, 2013 | 166 | 2013 |
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor M Ban, A Goris, ÅR Lorentzen, A Baker, T Mihalova, G Ingram, DR Booth, ... European Journal of Human Genetics 17 (10), 1309-1313, 2009 | 157 | 2009 |
Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex LM Flornes, YT Bryceson, A Spurkland, JC Lorentzen, E Dissen, ... Immunogenetics 56, 506-517, 2004 | 145 | 2004 |
The expanding genetic overlap between multiple sclerosis and type 1 diabetes International Multiple Sclerosis Genetics Consortium Genes and immunity 10 (1), 11, 2009 | 144 | 2009 |
Low-frequency and rare-coding variation contributes to multiple sclerosis risk M Mitrovič, NA Patsopoulos, AH Beecham, T Dankowski, A Goris, ... Cell 175 (6), 1679-1687. e7, 2018 | 143 | 2018 |