The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder MJ Dalby, N Gadegaard, R Tare, A Andar, MO Riehle, P Herzyk, ... Nature materials 6 (12), 997-1003, 2007 | 2731 | 2007 |
Osteogenesis and angiogenesis: the potential for engineering bone JM Kanczler, RO Oreffo Eur Cell Mater 15 (2), 100-114, 2008 | 1292 | 2008 |
Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate MJ Dalby, N Gadegaard, ROC Oreffo Nature materials 13 (6), 558-569, 2014 | 1071 | 2014 |
Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. IR Garrett, BF Boyce, RO Oreffo, L Bonewald, J Poser, GR Mundy The Journal of clinical investigation 85 (3), 632-639, 1990 | 1039 | 1990 |
Bone tissue engineering: hope vs hype FRAJ Rose, ROC Oreffo Biochemical and biophysical research communications 292 (1), 1-7, 2002 | 850 | 2002 |
Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency RJ McMurray, N Gadegaard, PM Tsimbouri, KV Burgess, LE McNamara, ... Nature materials 10 (8), 637-644, 2011 | 841 | 2011 |
Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration D Tang, RS Tare, LY Yang, DF Williams, KL Ou, ROC Oreffo Biomaterials 83, 363-382, 2016 | 618 | 2016 |
Quality of life in sarcopenia and frailty R Rizzoli, JY Reginster, JF Arnal, I Bautmans, C Beaudart, ... Calcified tissue international 93, 101-120, 2013 | 516 | 2013 |
Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions CE Forristal, KL Wright, NA Hanley, ROC Oreffo, FD Houghton Reproduction (Cambridge, England) 139 (1), 85, 2010 | 483 | 2010 |
Nanotopographical control of stem cell differentiation LE McNamara, RJ McMurray, MJP Biggs, F Kantawong, ROC Oreffo, ... Journal of tissue engineering 1 (1), 120623, 2010 | 435 | 2010 |
Association between the abnormal expression of matrix‐degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions HI Roach, N Yamada, KSC Cheung, S Tilley, NMP Clarke, ROC Oreffo, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2005 | 412 | 2005 |
Osteoprogenitor response to semi-ordered and random nanotopographies MJ Dalby, D McCloy, M Robertson, H Agheli, D Sutherland, S Affrossman, ... Biomaterials 27 (15), 2980-2987, 2006 | 394 | 2006 |
Activation of the bone-derived latent TGF beta complex by isolated osteoclasts ROC Oreffo, GR Mundy, SM Seyedin, LF Bonewald Biochemical and biophysical research communications 158 (3), 817-823, 1989 | 367 | 1989 |
Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification XB Yang, HI Roach, NMP Clarke, SM Howdle, R Quirk, KM Shakesheff, ... Bone 29 (6), 523-531, 2001 | 366 | 2001 |
Osteoprogenitor response to defined topographies with nanoscale depths MJ Dalby, D McCloy, M Robertson, CDW Wilkinson, ROC Oreffo Biomaterials 27 (8), 1306-1315, 2006 | 353 | 2006 |
Clay: new opportunities for tissue regeneration and biomaterial design JI Dawson, ROC Oreffo Advanced Materials 25 (30), 4069-4086, 2013 | 338 | 2013 |
Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells T Sjöström, MJ Dalby, A Hart, R Tare, ROC Oreffo, B Su Acta biomaterialia 5 (5), 1433-1441, 2009 | 315 | 2009 |
The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells MJP Biggs, RG Richards, N Gadegaard, CDW Wilkinson, ROC Oreffo, ... Biomaterials 30 (28), 5094-5103, 2009 | 314 | 2009 |
Mesenchymal stem cells: lineage, plasticity, and skeletal therapeutic potential ROC Oreffo, C Cooper, C Mason, M Clements Stem cell reviews 1, 169-178, 2005 | 313 | 2005 |
The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation JM Kanczler, PJ Ginty, L White, NMP Clarke, SM Howdle, KM Shakesheff, ... Biomaterials 31 (6), 1242-1250, 2010 | 309 | 2010 |