Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation SJ Humphrey, DE James, M Mann Trends in Endocrinology & Metabolism 26 (12), 676-687, 2015 | 541 | 2015 |
High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics SJ Humphrey, SB Azimifar, M Mann Nature Biotechnology 33, 990-995, 2015 | 460 | 2015 |
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2 SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ... Cell metabolism 17 (6), 1009-1020, 2013 | 438 | 2013 |
Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ... Cell metabolism 22 (5), 922-935, 2015 | 401 | 2015 |
A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation G Yang, DS Murashige, SJ Humphrey, DE James Cell reports 12 (6), 937-943, 2015 | 358 | 2015 |
Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology MS Robles, SJ Humphrey, M Mann Cell Metabolism 25 (1), 118-127, 2017 | 345 | 2017 |
High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform SJ Humphrey, O Karayel, DE James, M Mann Nature protocols 13 (9), 1897, 2018 | 273 | 2018 |
Illuminating the dark phosphoproteome EJ Needham, BL Parker, T Burykin, DE James, SJ Humphrey Science signaling 12 (565), eaau8645, 2019 | 262 | 2019 |
MaxDIA enables library-based and library-free data-independent acquisition proteomics P Sinitcyn, H Hamzeiy, F Salinas Soto, D Itzhak, F McCarthy, C Wichmann, ... Nature Biotechnology 39 (12), 1563-1573, 2021 | 150 | 2021 |
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection RJ Mills, SJ Humphrey, PRJ Fortuna, M Lor, SR Foster, GA Quaife-Ryan, ... Cell 184 (8), 2167-2182. e22, 2021 | 147 | 2021 |
Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency P Yang, SJ Humphrey, S Cinghu, R Pathania, AJ Oldfield, D Kumar, ... Cell Systems, 2019 | 125 | 2019 |
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ... eLife 7, e32111, 2018 | 117 | 2018 |
mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes AY Minard, SX Tan, P Yang, DJ Fazakerley, W Domanova, BL Parker, ... Cell Reports 17 (1), 29-36, 2016 | 112 | 2016 |
In vivo brain GPCR signaling elucidated by phosphoproteomics JJ Liu, K Sharma, L Zangrandi, C Chen, SJ Humphrey, YT Chiu, M Spetea, ... Science 360 (6395), eaao4927, 2018 | 105 | 2018 |
Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion F Sacco, SJ Humphrey, J Cox, M Mischnik, A Schulte, T Klabunde, ... Nature Communications 7 (1), 13250, 2016 | 89 | 2016 |
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 88 | 2019 |
Proteomic Analysis of Human Plasma during Intermittent Fasting DJ Harney, AT Hutchison, L Hatchwell, SJ Humphrey, DE James, ... Journal of proteome research 18 (5), 2228-2240, 2019 | 83 | 2019 |
Phosphoproteomics Reveals the GSK3-PDX1 Axis as a Key Pathogenic Signaling Node in Diabetic Islets F Sacco, A Seelig, SJ Humphrey, N Krahmer, F Volta, A Reggio, ... Cell metabolism 29 (6), 1422-1432. e3, 2019 | 74 | 2019 |
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry BL Parker, G Yang, SJ Humphrey, R Chaudhuri, X Ma, S Peterman, ... Science Signaling 8 (380), rs6-rs6, 2015 | 73 | 2015 |
PhosR enables processing and functional analysis of phosphoproteomic data HJ Kim, T Kim, ... Cell Reports 34 (8), 108771, 2021 | 65 | 2021 |