Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder HM Abdolmaleky, K Cheng, SV Faraone, M Wilcox, SJ Glatt, F Gao, ... Human molecular genetics 15 (21), 3132-3145, 2006 | 587 | 2006 |
TGFβ Signaling in Tumor Initiation, Epithelial‐to‐Mesenchymal Transition, and Metastasis P Papageorgis Journal of oncology 2015 (1), 587193, 2015 | 244 | 2015 |
Smad4 inactivation promotes malignancy and drug resistance of colon cancer P Papageorgis, K Cheng, S Ozturk, Y Gong, AW Lambert, ... Cancer research 71 (3), 998-1008, 2011 | 239 | 2011 |
Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder HM Abdolmaleky, S Yaqubi, P Papageorgis, AW Lambert, S Ozturk, ... Schizophrenia research 129 (2-3), 183-190, 2011 | 230 | 2011 |
Role of TGFβ in regulation of the tumor microenvironment and drug delivery P Papageorgis, T Stylianopoulos International journal of oncology 46 (3), 933-943, 2015 | 222 | 2015 |
Smad signaling is required to maintain epigenetic silencing during breast cancer progression P Papageorgis, AW Lambert, S Ozturk, F Gao, H Pan, U Manne, ... Cancer research 70 (3), 968-978, 2010 | 222 | 2010 |
The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities CM Neophytou, M Panagi, T Stylianopoulos, P Papageorgis Cancers 13 (9), 2053, 2021 | 206 | 2021 |
Molecular mechanisms and emerging therapeutic targets of triple-negative breast cancer metastasis C Neophytou, P Boutsikos, P Papageorgis Frontiers in oncology 8, 31, 2018 | 163 | 2018 |
Pirfenidone normalizes the tumor microenvironment to improve chemotherapy C Polydorou, F Mpekris, P Papageorgis, C Voutouri, T Stylianopoulos Oncotarget 8 (15), 24506, 2017 | 157 | 2017 |
Apoptosis deregulation and the development of cancer multi-drug resistance CM Neophytou, IP Trougakos, N Erin, P Papageorgis Cancers 13 (17), 4363, 2021 | 150 | 2021 |
TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity M Panagi, C Voutouri, F Mpekris, P Papageorgis, MR Martin, JD Martin, ... Theranostics 10 (4), 1910, 2020 | 135 | 2020 |
Remodeling components of the tumor microenvironment to enhance cancer therapy V Gkretsi, A Stylianou, P Papageorgis, C Polydorou, T Stylianopoulos Frontiers in oncology 5, 214, 2015 | 132 | 2015 |
D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells CM Neophytou, C Constantinou, P Papageorgis, AI Constantinou Biochemical pharmacology 89 (1), 31-42, 2014 | 132 | 2014 |
Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors C Voutouri, F Mpekris, P Papageorgis, AD Odysseos, T Stylianopoulos PloS one 9 (8), e104717, 2014 | 123 | 2014 |
Hyaluronan-derived swelling of solid tumors, the contribution of collagen and cancer cells, and implications for cancer therapy C Voutouri, C Polydorou, P Papageorgis, V Gkretsi, T Stylianopoulos Neoplasia 18 (12), 732-741, 2016 | 120 | 2016 |
Dexamethasone increases cisplatin-loaded nanocarrier delivery and efficacy in metastatic breast cancer by normalizing the tumor microenvironment JD Martin, M Panagi, C Wang, TT Khan, MR Martin, C Voutouri, K Toh, ... ACS nano 13 (6), 6396-6408, 2019 | 106 | 2019 |
Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo-and nanotherapeutics in a size-independent manner P Papageorgis, C Polydorou, F Mpekris, C Voutouri, E Agathokleous, ... Scientific reports 7 (1), 46140, 2017 | 103 | 2017 |
Solid stress facilitates fibroblasts activation to promote pancreatic cancer cell migration M Kalli, P Papageorgis, V Gkretsi, T Stylianopoulos Annals of biomedical engineering 46, 657-669, 2018 | 85 | 2018 |
Mechanisms of metastatic tumor dormancy and implications for cancer therapy CM Neophytou, TC Kyriakou, P Papageorgis International journal of molecular sciences 20 (24), 6158, 2019 | 83 | 2019 |
Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis P Papageorgis, S Ozturk, AW Lambert, CM Neophytou, A Tzatsos, ... Breast Cancer Research 17, 1-15, 2015 | 82 | 2015 |