Peptide nucleic acid (PNA) binding-mediated induction of human γ-globin gene expression G Wang, X Xu, B Pace, DA Dean, PM Glazer, P Chan, SR Goodman, ... Nucleic acids research 27 (13), 2806-2813, 1999 | 146 | 1999 |
RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis M Zhang, X Zhu, Y Zhang, Y Cai, J Chen, S Sivaprakasam, A Gurav, W Pi, ... Cell Death & Differentiation 22 (12), 1922-1934, 2015 | 145 | 2015 |
UFBP1, a key component of the Ufm1 conjugation system, is essential for ufmylation-mediated regulation of erythroid development Y Cai, W Pi, S Sivaprakasam, X Zhu, M Zhang, J Chen, L Makala, C Lu, ... PLoS genetics 11 (11), e1005643, 2015 | 141 | 2015 |
Effects of N‐acetylcysteine on dense cell formation in sickle cell disease BS Pace, A Shartava, A Pack‐Mabien, M Mulekar, A Ardia, SR Goodman American journal of hematology 73 (1), 26-32, 2003 | 122 | 2003 |
Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo BS Pace, GL White, GJ Dover, MS Boosalis, DV Faller, SP Perrine Blood, The Journal of the American Society of Hematology 100 (13), 4640-4648, 2002 | 112 | 2002 |
Understanding mechanisms of γ‐globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction BS Pace, S Zein Developmental dynamics: an official publication of the American Association …, 2006 | 102 | 2006 |
p38 MAP kinase activation mediates γ-globin gene induction in erythroid progenitors BS Pace, X Qian, J Sangerman, SF Ofori-Acquah, BS Baliga, J Han, ... Experimental Hematology 31 (11), 1089-1096, 2003 | 102 | 2003 |
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice RP Hebbel, GM Vercellotti, BS Pace, AN Solovey, R Kollander, ... Blood, The Journal of the American Society of Hematology 115 (12), 2483-2490, 2010 | 93 | 2010 |
Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves γ-globin activation by CREB1 and ATF-2 J Sangerman, MS Lee, X Yao, E Oteng, CH Hsiao, W Li, S Zein, ... Blood 108 (10), 3590-3599, 2006 | 87 | 2006 |
Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation MS Boosalis, R Bandyopadhyay, EH Bresnick, BS Pace, K Van DeMark, ... Blood, The Journal of the American Society of Hematology 97 (10), 3259-3267, 2001 | 87 | 2001 |
Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in … S Subbanna, NN Nagre, NS Umapathy, BS Pace, BS Basavarajappa International Journal of Neuropsychopharmacology 18 (5), pyu028, 2015 | 77 | 2015 |
Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for γ-globin gene activation TF Lou, M Singh, A Mackie, W Li, BS Pace Experimental Biology and Medicine 234 (11), 1374-1382, 2009 | 71 | 2009 |
HIV-1 Tat Protein-mediated Transactivation of the HIV-1 Long Terminal Repeat Promoter Is Potentiated by a Novel Nuclear Tat-interacting Protein of110 kDa, Tip110 Y Liu, J Li, BO Kim, BS Pace, JJ He Journal of Biological Chemistry 277 (26), 23854-23863, 2002 | 65 | 2002 |
Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of the l-arginine–nitric oxide signaling pathway J Haynes Jr, BS Baliga, B Obiako, S Ofori-Acquah, B Pace Blood 103 (10), 3945-3950, 2004 | 64 | 2004 |
Fetal hemoglobin induction by acetate, a product of butyrate catabolism G Stamatoyannopoulos, CA Blau, B Nakamoto, B Josephson, Q Li, ... Blood 84 (9), 3198-3204, 1994 | 55 | 1994 |
Mechanism for fetal hemoglobin induction by hydroxyurea in sickle cell erythroid progenitors BS Baliga, BS Pace, HH Chen, AK Shah, YM Yang American journal of hematology 65 (3), 227-233, 2000 | 53 | 2000 |
alpha-Amino butyric acid cannot reactivate the silenced gamma gene of the beta locus YAC transgenic mouse B Pace, Q Li, K Peterson, G Stamatoyannopoulos | 53 | 1994 |
Fetal hemoglobin induction by histone deacetylase inhibitors involves generation of reactive oxygen species CH Hsiao, W Li, TF Lou, BS Baliga, BS Pace Experimental hematology 34 (3), 264-273, 2006 | 51 | 2006 |
MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease B Li, X Zhu, CM Ward, A Starlard-Davenport, M Takezaki, A Berry, A Ward, ... Experimental hematology 70, 85-96. e5, 2019 | 50 | 2019 |
Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease S Krishnamoorthy, B Pace, D Gupta, S Sturtevant, B Li, L Makala, ... JCI insight 2 (20), 2017 | 45 | 2017 |