| Membrane proteins solubilized intact in lipid containing nanoparticles bounded by styrene maleic acid copolymer TJ Knowles, R Finka, C Smith, YP Lin, T Dafforn, M Overduin Journal of the American Chemical Society 131 (22), 7484-7485, 2009 | 603 | 2009 |
| A method for detergent-free isolation of membrane proteins in their local lipid environment SC Lee, TJ Knowles, VLG Postis, M Jamshad, RA Parslow, YP Lin, ... Nature protocols 11 (7), 1149-1162, 2016 | 407 | 2016 |
| Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K+ channel: the power of native nanodiscs JM Dörr, MC Koorengevel, M Schäfer, AV Prokofyev, S Scheidelaar, ... Proceedings of the National Academy of Sciences 111 (52), 18607-18612, 2014 | 387 | 2014 |
| A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain DJ Owen, Y Vallis, MEM Noble, JB Hunter, TR Dafforn, PR Evans, ... Cell 97 (6), 805-815, 1999 | 349 | 1999 |
| Linear dichroism and circular dichroism: a textbook on polarized-light spectroscopy B Nordén, A Rodger, T Dafforn Royal Society of Chemistry, 2019 | 340 | 2019 |
| Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53 TH Millard, G Bompard, MY Heung, TR Dafforn, DJ Scott, LM Machesky, ... The EMBO journal 24 (2), 240-250, 2005 | 283 | 2005 |
| A kinetic mechanism for the polymerization of α1-antitrypsin TR Dafforn, R Mahadeva, PR Elliott, P Sivasothy, DA Lomas Journal of Biological Chemistry 274 (14), 9548-9555, 1999 | 273 | 1999 |
| Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum T Laursen, J Borch, C Knudsen, K Bavishi, F Torta, HJ Martens, ... Science 354 (6314), 890-893, 2016 | 264 | 2016 |
| Detergent-free purification of ABC (ATP-binding-cassette) transporters S Gulati, M Jamshad, TJ Knowles, KA Morrison, R Downing, N Cant, ... Biochemical Journal 461 (2), 269-278, 2014 | 244 | 2014 |
| The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy V Postis, S Rawson, JK Mitchell, SC Lee, RA Parslow, TR Dafforn, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (2), 496-501, 2015 | 230 | 2015 |
| Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins M Jamshad, V Grimard, I Idini, TJ Knowles, MR Dowle, N Schofield, ... Nano Research 8, 774-789, 2015 | 225 | 2015 |
| Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational disease PR Elliott, XY Pei, TR Dafforn, DA Lomas Protein Science 9 (7), 1274-1281, 2000 | 223 | 2000 |
| Heteropolymerization of S, I, and Z α1-antitrypsin and liver cirrhosis R Mahadeva, WSW Chang, TR Dafforn, DJ Oakley, RC Foreman, J Calvin, ... The Journal of clinical investigation 103 (7), 999-1006, 1999 | 222 | 1999 |
| Inactive conformation of the serpin α1-antichymotrypsin indicates two-stage insertion of the reactive loop: Implications for inhibitory function and conformational … B Gooptu, B Hazes, WSW Chang, TR Dafforn, RW Carrell, RJ Read, ... Proceedings of the National Academy of Sciences 97 (1), 67-72, 2000 | 218 | 2000 |
| G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent M Jamshad, J Charlton, YP Lin, SJ Routledge, Z Bawa, TJ Knowles, ... Bioscience reports 35 (2), e00188, 2015 | 206 | 2015 |
| 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization: implications for the prevention of Z α1-antitrypsin-related cirrhosis R Mahadeva, TR Dafforn, RW Carrell, DA Lomas Journal of Biological Chemistry 277 (9), 6771-6774, 2002 | 192 | 2002 |
| Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody PA Smethurst, L Joutsi-Korhonen, MN O'Connor, E Wilson, NS Jennings, ... Blood 103 (3), 903-911, 2004 | 170 | 2004 |
| Pathogenic α1-antitrypsin polymers are formed by reactive loop-β-sheet A linkage P Sivasothy, TR Dafforn, PGW Gettins, DA Lomas Journal of Biological Chemistry 275 (43), 33663-33668, 2000 | 164 | 2000 |
| The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesis TR Dafforn, M Della, AD Miller Journal of Biological Chemistry 276 (52), 49310-49319, 2001 | 162 | 2001 |
| Membrane protein extraction and purification using styrene–maleic acid (SMA) copolymer: effect of variations in polymer structure KA Morrison, A Akram, A Mathews, ZA Khan, JH Patel, C Zhou, DJ Hardy, ... Biochemical Journal 473 (23), 4349-4360, 2016 | 156 | 2016 |
Alison RodgerProfessor of Biophysical Chemistry, Macquarie University在 anu.edu.au 的电子邮件经过验证
