Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 636 | 2020 |
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 384 | 2020 |
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2 CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ... Nature chemical biology 17 (1), 113-121, 2021 | 90 | 2021 |
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... BioRxiv, 2020 | 65 | 2020 |
Fusion protein strategies for cryo-EM study of G protein-coupled receptors K Zhang, H Wu, N Hoppe, A Manglik, Y Cheng Nature Communications 13 (1), 4366, 2022 | 37 | 2022 |
Autoantibody mimicry of hormone action at the thyrotropin receptor B Faust, CB Billesbølle, CM Suomivuori, I Singh, K Zhang, N Hoppe, ... Nature 609 (7928), 846-853, 2022 | 27 | 2022 |
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB ED Crawford, I Acosta, V Ahyong, EC Anderson, S Arevalo, D Asarnow, ... PLoS pathogens 16 (10), e1008966, 2020 | 23 | 2020 |
Epistasis shapes the fitness landscape of an allosteric specificity switch KK Nishikawa, N Hoppe, R Smith, C Bingman, S Raman Nature Communications 12 (1), 5562, 2021 | 15 | 2021 |
Robust sequence determinants of α-synuclein toxicity in yeast implicate membrane binding RW Newberry, T Arhar, J Costello, GC Hartoularos, AM Maxwell, ... ACS chemical biology 15 (8), 2137-2153, 2020 | 11 | 2020 |
Consortium QSB, Walter P, Manglik A M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473, 2020 | 10 | 2020 |
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway N Hoppe, S Harrison, SH Hwang, Z Chen, M Karelina, I Deshpande, ... Nature Structural & Molecular Biology 31 (4), 667-677, 2024 | 6 | 2024 |
Autoantibody and hormone activation of the thyrotropin G protein-coupled receptor B Faust, I Singh, K Zhang, N Hoppe, AFM Pinto, Y Muftuoglu, ... bioRxiv, 2022.01. 06.475289, 2022 | 4 | 2022 |
Molecular basis of proton-sensing by G protein-coupled receptors MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrota, PR Grimes, ... bioRxiv, 2024 | 1 | 2024 |
Sars-cov2 neutralizing single domain antibody constructs P Walter, A Manglik, M Schoof, B Faust, N Hoppe, R Saunders, ... US Patent App. 17/998,605, 2023 | | 2023 |
Structural Insights into Orphan G Protein-Coupled Receptors: A Focus on GPR161 and Proton-Sensing GPCRs N Hoppe University of California, San Francisco, 2023 | | 2023 |
Data for EMSL Project 51817 from May 2021 A Manglik, I Deshpande, N Hoppe, B Faust, C Billesboelle Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2021 | | 2021 |
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... bioRxiv, 2020 | | 2020 |
Validation Report Service MS Schoof, BF Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... | | |