关注
Lijun "Josh" Sun
Lijun "Josh" Sun
ImmuneSensor Therapeutics
在 immunesensor.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
L Sun, J Wu, F Du, X Chen, ZJ Chen
Science 339 (6121), 786-791, 2013
42472013
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3
RB Seth, L Sun, CK Ea, ZJ Chen
Cell 122 (5), 669-682, 2005
38042005
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
J Wu, L Sun, X Chen, F Du, H Shi, C Chen, ZJ Chen
Science 339 (6121), 826-830, 2013
22792013
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
MU Gack, YC Shin, CH Joo, T Urano, C Liang, L Sun, O Takeuchi, S Akira, ...
Nature 446 (7138), 916-920, 2007
18622007
Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
Q Chen, L Sun, ZJ Chen
Nature immunology 17 (10), 1142-1149, 2016
16842016
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
F Hou, L Sun, H Zheng, B Skaug, QX Jiang, ZJ Chen
Cell 146 (3), 448-461, 2011
13242011
Nonproteolytic functions of ubiquitin in cell signaling
ZJ Chen, LJ Sun
Molecular cell 33 (3), 275-286, 2009
10932009
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
XD Li, J Wu, D Gao, H Wang, L Sun, ZJ Chen
Science 341 (6152), 1390-1394, 2013
10922013
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
A Kanayama, RB Seth, L Sun, CK Ea, M Hong, A Shaito, YH Chiu, L Deng, ...
Molecular cell 15 (4), 535-548, 2004
10882004
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
D Gao, J Wu, YT Wu, F Du, C Aroh, N Yan, L Sun, ZJ Chen
Science 341 (6148), 903-906, 2013
10792013
Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING
X Zhang, H Shi, J Wu, X Zhang, L Sun, C Chen, ZJ Chen
Molecular cell 51 (2), 226-235, 2013
10252013
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
XD Li, L Sun, RB Seth, G Pineda, ZJ Chen
Proceedings of the National Academy of Sciences of the United States of …, 2005
9992005
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
L Sun, L Deng, CK Ea, ZP Xia, ZJ Chen
Molecular cell 14 (3), 289-301, 2004
8642004
The specific and essential role of MAVS in antiviral innate immune responses
Q Sun, L Sun, HH Liu, X Chen, RB Seth, J Forman, ZJ Chen
Immunity 24 (5), 633-642, 2006
7402006
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
W Zeng, L Sun, X Jiang, X Chen, F Hou, A Adhikari, M Xu, ZJ Chen
Cell 141 (2), 315-330, 2010
6762010
NLRX1 is a regulator of mitochondrial antiviral immunity
CB Moore, DT Bergstralh, JA Duncan, Y Lei, TE Morrison, ...
Nature 451 (7178), 573-577, 2008
6652008
The novel functions of ubiquitination in signaling
L Sun, ZJ Chen
Current opinion in cell biology 16 (2), 119-126, 2004
6502004
Direct activation of protein kinases by unanchored polyubiquitin chains
ZP Xia, L Sun, X Chen, G Pineda, X Jiang, A Adhikari, W Zeng, ZJ Chen
Nature 461 (7260), 114-119, 2009
6362009
Antiviral innate immunity pathways
RB Seth, L Sun, ZJ Chen
Cell research 16 (2), 141-147, 2006
6282006
cGAS is essential for the antitumor effect of immune checkpoint blockade
H Wang, S Hu, X Chen, H Shi, C Chen, L Sun, ZJ Chen
Proceedings of the National Academy of Sciences 114 (7), 1637-1642, 2017
4852017
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