Transformation of hematopoietic cells by BCR/ABL requires activation of a PI‐3k/Akt‐dependent pathway T Skorski, A Bellacosa, M Nieborowska‐Skorska, M Majewski, R Martinez, ... The EMBO journal, 1997 | 818 | 1997 |
Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity M Marzec, M Kasprzycka, R Lai, AB Gladden, P Wlodarski, E Tomczak, ... Blood 108 (5), 1744-1750, 2006 | 170 | 2006 |
Possible mechanisms of disease development in tuberous sclerosis J Jozwiak, S Jozwiak, P Wlodarski The lancet oncology 9 (1), 73-79, 2008 | 160 | 2008 |
Type II phosphatidylinositol 4-kinase β is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP YJ Wei, HQ Sun, M Yamamoto, P Wlodarski, K Kunii, M Martinez, ... Journal of Biological Chemistry 277 (48), 46586-46593, 2002 | 148 | 2002 |
BCR/ABL-mediated leukemogenesis requires the activity of the small GTP-binding protein Rac T Skorski, P Wlodarski, L Daheron, P Salomoni, M Nieborowska-Skorska, ... Proceedings of the National Academy of Sciences 95 (20), 11858-11862, 1998 | 141 | 1998 |
Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway M Marzec, M Kasprzycka, X Liu, M El-Salem, K Halasa, PN Raghunath, ... Oncogene 26 (38), 5606-5614, 2007 | 129 | 2007 |
Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase T Skorski, M Nieborowska-Skorska, P Wlodarski, D Perrotti, R Martinez, ... Proceedings of the National Academy of Sciences 93 (23), 13137-13142, 1996 | 113 | 1996 |
The SH3 domain contributes to BCR/ABL-dependent leukemogenesis in vivo: role in adhesion, invasion, and homing T Skorski, M Nieborowska-Skorska, P Wlodarski, M Wasik, R Trotta, ... Blood, The Journal of the American Society of Hematology 91 (2), 406-418, 1998 | 111 | 1998 |
Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf M Marzec, M Kasprzycka, X Liu, PN Raghunath, P Wlodarski, MA Wasik Oncogene 26 (6), 813-821, 2007 | 107 | 2007 |
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3 M Marzec, M Kasprzycka, A Ptasznik, P Wlodarski, Q Zhang, N Odum, ... Laboratory investigation 85 (12), 1544-1554, 2005 | 104 | 2005 |
Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase IIα B Barylko, YS Mao, P Wlodarski, G Jung, DD Binns, HQ Sun, HL Yin, ... Journal of Biological Chemistry 284 (15), 9994-10003, 2009 | 92 | 2009 |
Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice T Skorski, M Nieborowska-Skorska, P Wlodarski, G Zon, RV Iozzo, ... | 91 | 1996 |
Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal … P Wlodarski, M Kasprzycka, X Liu, M Marzec, ES Robertson, A Slupianek, ... Cancer research 65 (17), 7800-7808, 2005 | 89 | 2005 |
The BAG3 gene variants in Polish patients with dilated cardiomyopathy: four novel mutations and a genotype-phenotype correlation. PR Franaszczyk M, Bilinska ZT, Sobieszczańska-Małek M, Michalak E, Sleszycka ... J Transl Med. 12, 192, 2014 | 77* | 2014 |
Role of p53 in hematopoietic recovery after cytotoxic treatment P Wlodarski, M Wasik, MZ Ratajczak, C Sevignani, G Hoser, J Kawiak, ... Blood, The Journal of the American Society of Hematology 91 (8), 2998-3006, 1998 | 73 | 1998 |
Treatment of Philadelphia 1 Leukemia in Severe Combined Immunodeficient Mice by Combination of Cyclophosphamide and bcr/abl Antisense … T Skorski, M Nieborowska-Skorska, P Wlodarski, D Perrotti, M Majewski, ... Journal of the National Cancer Institute 89 (2), 124-133, 1997 | 72 | 1997 |
Pathogenesis of medulloblastoma and current treatment outlook J Jozwiak, W Grajkowska, P Wlodarski Medicinal Research Reviews 27 (6), 869-890, 2007 | 50 | 2007 |
Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders M El-Salem, PN Raghunath, M Marzec, P Wlodarski, D Tsai, E Hsi, ... Laboratory Investigation 87 (1), 29-39, 2007 | 49 | 2007 |
Molecular determinants of activation and membrane targeting of phosphoinositol 4-kinase IIβ G Jung, J Wang, P Wlodarski, B Barylko, DD Binns, H Shu, HL Yin, ... Biochemical Journal 409 (2), 501-509, 2008 | 48 | 2008 |
Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene. C Sevignani, P Wlodarski, J Kirillova, WE Mercer, KG Danielson, RV Iozzo, ... The Journal of clinical investigation 101 (8), 1572-1580, 1998 | 45 | 1998 |