Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging S Bhaskar, F Tian, T Stoeger, W Kreyling, JM de la Fuente, V Grazú, ... Particle and fibre toxicology 7, 1-25, 2010 | 592 | 2010 |
Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice T Stoeger, C Reinhard, S Takenaka, A Schroeppel, E Karg, B Ritter, ... Environmental health perspectives 114 (3), 328-333, 2006 | 547 | 2006 |
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis M Strunz, LM Simon, M Ansari, JJ Kathiriya, I Angelidis, CH Mayr, ... Nature communications 11 (1), 3559, 2020 | 427 | 2020 |
Failure to degrade poly (ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality DW Koh, AM Lawler, MF Poitras, M Sasaki, S Wattler, MC Nehls, T Stöger, ... Proceedings of the National Academy of Sciences 101 (51), 17699-17704, 2004 | 372 | 2004 |
Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung O Schmid, T Stoeger Journal of Aerosol Science 99, 133-143, 2016 | 367 | 2016 |
In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models J Conde, F Tian, Y Hernández, C Bao, D Cui, KP Janssen, MR Ibarra, ... Biomaterials 34 (31), 7744-7753, 2013 | 185 | 2013 |
Health effects of ambient particulate matter—biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures KL Maier, F Alessandrini, I Beck-Speier, TP Josef Hofer, S Diabaté, ... Inhalation toxicology 20 (3), 319-337, 2008 | 170 | 2008 |
Inflammatory and oxidative stress responses of an alveolar epithelial cell line to airborne zinc oxide nanoparticles at the air‐liquid interface: A comparison with conventional … AG Lenz, E Karg, E Brendel, H Hinze-Heyn, KL Maier, O Eickelberg, ... BioMed research international 2013 (1), 652632, 2013 | 156 | 2013 |
Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications A Beyerle, M Irmler, J Beckers, T Kissel, T Stoeger Molecular pharmaceutics 7 (3), 727-737, 2010 | 156 | 2010 |
Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale S Halappanavar, S Van Den Brule, P Nymark, L Gaté, C Seidel, ... Particle and Fibre Toxicology 17, 1-24, 2020 | 152 | 2020 |
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ... Nature genetics 47 (9), 969-978, 2015 | 145 | 2015 |
A multilaboratory toxicological assessment of a panel of 10 engineered nanomaterials to human health—ENPRA project—the highlights, limitations, and current and future challenges A Kermanizadeh, I Gosens, L MacCalman, H Johnston, PH Danielsen, ... Journal of Toxicology and Environmental Health, Part B 19 (1), 1-28, 2016 | 126 | 2016 |
Deducing in Vivo Toxicity of Combustion-Derived Nanoparticles from a Cell-Free Oxidative Potency Assay and Metabolic Activation of Organic Compounds T Stoeger, S Takenaka, B Frankenberger, B Ritter, E Karg, K Maier, ... Environmental Health Perspectives 117 (1), 54-60, 2009 | 125 | 2009 |
Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories NR Jacobsen, T Stoeger, S Van Den Brûle, AT Saber, A Beyerle, G Vietti, ... Food and Chemical Toxicology 85, 84-95, 2015 | 116 | 2015 |
Polymer-related off-target effects in non-viral siRNA delivery OM Merkel, A Beyerle, BM Beckmann, M Zheng, RK Hartmann, T Stöger, ... Biomaterials 32 (9), 2388-2398, 2011 | 115 | 2011 |
Efficient bioactive delivery of aerosolized drugs to human pulmonary epithelial cells cultured in air–liquid interface conditions AG Lenz, T Stoeger, D Cei, M Schmidmeir, N Semren, G Burgstaller, ... American journal of respiratory cell and molecular biology 51 (4), 526-535, 2014 | 113 | 2014 |
Inhibition of LTβR signalling activates WNT-induced regeneration in lung TM Conlon, G John-Schuster, D Heide, D Pfister, M Lehmann, Y Hu, ... Nature 588 (7836), 151-156, 2020 | 107 | 2020 |
Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator–activated receptor γ function (P465L PPARγ) in mice SL Gray, ED Nora, J Grosse, M Manieri, T Stoeger, G Medina-Gomez, ... Diabetes 55 (10), 2669-2677, 2006 | 106 | 2006 |
Comparative in vivo study of poly (ethylene imine)/siRNA complexes for pulmonary delivery in mice A Beyerle, A Braun, O Merkel, F Koch, T Kissel, T Stoeger Journal of controlled release 151 (1), 51-56, 2011 | 105 | 2011 |
Vascular Effects of Multiwalled Carbon Nanotubes in Dyslipidemic ApoE−/− Mice and Cultured Endothelial Cells Y Cao, NR Jacobsen, PH Danielsen, AG Lenz, T Stoeger, S Loft, H Wallin, ... toxicological sciences 138 (1), 104-116, 2014 | 102 | 2014 |