Resident macrophages mediate islet amyloid polypeptide–induced islet IL-1β production and β-cell dysfunction CY Westwell-Roper, JA Ehses, CB Verchere Diabetes 63 (5), 1698-1711, 2014 | 248 | 2014 |
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction C Westwell-Roper, DL Dai, G Soukhatcheva, KJ Potter, N van Rooijen, ... The journal of immunology 187 (5), 2755-2765, 2011 | 218 | 2011 |
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function JK Kruit, N Wijesekara, C Westwell-Roper, T Vanmierlo, W De Haan, ... Diabetes 61 (3), 659-664, 2012 | 136 | 2012 |
TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6 D Nackiewicz, M Dan, W He, R Kim, A Salmi, S Rütti, C Westwell-Roper, ... Diabetologia 57, 1645-1654, 2014 | 131 | 2014 |
Metabolic stress, IAPP and islet amyloid J Montane, A Klimek‐Abercrombie, KJ Potter, C Westwell‐Roper, ... Diabetes, Obesity and Metabolism 14, 68-77, 2012 | 119 | 2012 |
Toll‐like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes C Westwell‐Roper, D Nackiewicz, M Dan, JA Ehses Immunology and cell biology 92 (4), 314-323, 2014 | 89 | 2014 |
IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice CY Westwell-Roper, CA Chehroudi, HC Denroche, JA Courtade, ... Diabetologia 58, 575-585, 2015 | 75 | 2015 |
Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2 G Jing, C Westwell-Roper, J Chen, G Xu, CB Verchere, A Shalev Journal of Biological Chemistry 289 (17), 11807-11815, 2014 | 66 | 2014 |
Death and dysfunction of transplanted β-cells: lessons learned from type 2 diabetes? KJ Potter, CY Westwell-Roper, AM Klimek-Abercrombie, GL Warnock, ... Diabetes 63 (1), 12-19, 2014 | 63 | 2014 |
Differential activation of innate immune pathways by distinct islet amyloid polypeptide (IAPP) aggregates C Westwell-Roper, HC Denroche, JA Ehses, CB Verchere Journal of Biological Chemistry 291 (17), 8908-8917, 2016 | 47 | 2016 |
Food‐allergy‐specific anxiety and distress in parents of children with food allergy: A systematic review C Westwell‐Roper, S To, G Andjelic, C Lu, B Lin, L Soller, ES Chan, ... Pediatric Allergy and Immunology 33 (1), e13695, 2022 | 41 | 2022 |
Npas4 is a novel activity–regulated cytoprotective factor in pancreatic β-cells PV Sabatini, NAJ Krentz, B Zarrouki, CY Westwell-Roper, C Nian, RA Uy, ... Diabetes 62 (8), 2808-2820, 2013 | 40 | 2013 |
Immune-related comorbidities in childhood-onset obsessive compulsive disorder: lifetime prevalence in the obsessive compulsive disorder collaborative genetics association study C Westwell-Roper, KA Williams, J Samuels, OJ Bienvenu, B Cullen, ... Journal of child and adolescent psychopharmacology 29 (8), 615-624, 2019 | 33 | 2019 |
Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international … C Westwell-Roper, JM Lubieniecka, KL Brown, KA Morishita, C Mammen, ... Pediatric Rheumatology 15, 1-10, 2017 | 26 | 2017 |
ABCA1 deficiency and cellular cholesterol accumulation increases islet amyloidogenesis in mice N Wijesekara, A Kaur, C Westwell-Roper, D Nackiewicz, G Soukhatcheva, ... Diabetologia 59, 1242-1246, 2016 | 26 | 2016 |
Challenges in the diagnosis and treatment of pediatric obsessive–compulsive disorder C Westwell-Roper, SE Stewart Indian journal of psychiatry 61 (Suppl 1), S119-S130, 2019 | 25 | 2019 |
Islet allograft rejection is independent of toll-like receptor signaling in mice MJH Hutton, C Westwell-Roper, G Soukhatcheva, A Plesner, JP Dutz, ... Transplantation 88 (9), 1075-1080, 2009 | 25 | 2009 |
Activating the NLRP3 inflammasome using the amyloidogenic peptide IAPP C Westwell-Roper, A Dunne, ML Kim, CB Verchere, SL Masters The Inflammasome: Methods and Protocols, 9-18, 2013 | 22 | 2013 |
Is there a role for the adaptive immune system in pancreatic beta cell failure in type 2 diabetes? C Westwell-Roper, JA Ehses Diabetologia 57, 447-450, 2014 | 17 | 2014 |
Diagnosis and management of depression in adolescents DJ Korczak, C Westwell-Roper, R Sassi CMAJ 195 (21), E739-E746, 2023 | 11 | 2023 |