Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response Science 364 (6439), 485-491, 2019 | 468 | 2019 |
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells GQ Sun, P Ye, K Murai, MF Lang, S Li, H Zhang, W Li, C Fu, J Yin, ... Nature communications 2 (1), 529, 2011 | 328 | 2011 |
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types D Chowell, SK Yoo, C Valero, A Pastore, C Krishna, M Lee, D Hoen, ... Nature Biotechnology, 2021 | 164 | 2021 |
Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy Nature Cancer, https://doi.org/10.1038/s43018-020-00139, 2020 | 145* | 2020 |
Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas JTHTAC Yuxiang Wang, Aaron T. Wild, Sevin Turcan, Wei H. Wu, Carlie Sigel ... Science Advances 6 (17), eaaz3221, 2020 | 91 | 2020 |
Berbamine Inhibits the Growth of Liver Cancer Cells and Cancer-Initiating Cells by Targeting Ca2+/Calmodulin-Dependent Protein Kinase II Z Meng, T Li, X Ma, X Wang, C Van Ness, Y Gan, H Zhou, J Tang, G Lou, ... Molecular cancer therapeutics 12 (10), 2067-2077, 2013 | 89 | 2013 |
Bile acid receptors and liver cancer X Wang, X Fu, C Van Ness, Z Meng, X Ma, W Huang Current pathobiology reports 1, 29-35, 2013 | 86 | 2013 |
Stabilization of the c-Myc protein by CAMKIIγ promotes T cell lymphoma Y Gu, J Zhang, X Ma, B Kim, H Wang, J Li, Y Pan, Y Xu, L Ding, L Yang, ... Cancer cell 32 (1), 115-128. e7, 2017 | 81 | 2017 |
GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells G Lou, X Ma, X Fu, Z Meng, W Zhang, YD Wang, C Van Ness, D Yu, R Xu, ... PLoS One 9 (4), e93567, 2014 | 76 | 2014 |
Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells J Zhang, Y Gan, H Li, J Yin, X He, L Lin, S Xu, Z Fang, B Kim, L Gao, ... nature communications, 2022 | 47 | 2022 |
Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity X Ma, N Riaz, RM Samstein, M Lee, V Makarov, C Valero, D Chowell, ... Nature genetics 54 (7), 996-1012, 2022 | 42 | 2022 |
Vertical sleeve gastrectomy confers metabolic improvements by reducing intestinal bile acids and lipid absorption in mice L Ding, E Zhang, Q Yang, L Jin, KM Sousa, B Dong, Y Wang, J Tu, X Ma, ... Proceedings of the National Academy of Sciences 118 (6), e2019388118, 2021 | 35 | 2021 |
FXR blocks the growth of liver cancer cells through inhibiting mTOR-s6K pathway X Huang, Y Zeng, X Wang, X Ma, Q Li, N Li, H Su, W Huang Biochemical and biophysical research communications 474 (2), 351-356, 2016 | 30 | 2016 |
CAMK2γ in intestinal epithelial cells modulates colitis-associated colorectal carcinogenesis via enhancing STAT3 activation X Ma, Z Meng, L Jin, Z Xiao, X Wang, WM Tsark, L Ding, Y Gu, J Zhang, ... Oncogene 36 (28), 4060-4071, 2017 | 28 | 2017 |
Aberrant activation of CaMKIIγ accelerates chronic myeloid leukemia blast crisis XR Gu Y, Zheng W, Zhang J, Gan X, Ma X, Meng Z, Chen T, Lu X, Wu Z, Huang W Leukemia, 2016 | 22 | 2016 |
Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue Y Gu, H Zhou, Y Gan, J Zhang, J Chen, X Gan, H Li, W Zheng, Z Meng, ... Oncotarget 6 (17), 15111, 2015 | 21 | 2015 |
Myeloid adrenergic signaling via CaMKII forms a feedforward loop of catecholamine biosynthesis Y Luo, B Liu, X Yang, X Ma, X Zhang, DE Bragin, XO Yang, W Huang, ... Journal of Molecular Cell Biology 9 (5), 422-434, 2017 | 19 | 2017 |
A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell Renal Cell Carcinoma PM Rappold, L Vuong, J Leibold, NH Chakiryan, M Curry, F Kuo, E Sabio, ... Cancer Discovery, 2022 | 16 | 2022 |
Qa-1b Modulates Resistance to Anti–PD-1 Immune Checkpoint Blockade in Tumors with Defects in Antigen Processing X Zhang, E Sabio, C Krishna, X Ma, J Wang, H Jiang, JJ Havel, TA Chan Molecular Cancer Research 19 (6), 1076-1084, 2021 | 14 | 2021 |
Cellular transcriptomics: gelsolin negatively regulates the expression of apoptosis-associated genes and inhibits apoptosis in hepatocarcinoma cells Y Zhou, X Deng, X Ma, N Zang, H Li, G Li, D Li, C Li, W Huang, M He International Journal of Clinical and Experimental Pathology 8 (11), 13871, 2015 | 14 | 2015 |