The N-end rule pathway T Tasaki, SM Sriram, KS Park, YT Kwon Annual review of biochemistry 81 (1), 261-289, 2012 | 430 | 2012 |
A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons T Tasaki, LCF Mulder, A Iwamatsu, MJ Lee, IV Davydov, A Varshavsky, ... Molecular and cellular biology, 2005 | 411 | 2005 |
RGS4 and RGS5 are in vivo substrates of the N-end rule pathway MJ Lee, T Tasaki, K Moroi, JY An, S Kimura, IV Davydov, YT Kwon Proceedings of the National Academy of Sciences 102 (42), 15030-15035, 2005 | 290 | 2005 |
The mammalian N-end rule pathway: new insights into its components and physiological roles T Tasaki, YT Kwon Trends in biochemical sciences 32 (11), 520-528, 2007 | 206 | 2007 |
Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway YT Kwon, Z Xia, JY An, T Tasaki, IV Davydov, JW Seo, J Sheng, Y Xie, ... Molecular and cellular biology, 2003 | 177 | 2003 |
The substrate recognition domains of the N-end rule pathway T Tasaki, A Zakrzewska, DD Dudgeon, Y Jiang, JS Lazo, YT Kwon Journal of Biological Chemistry 284 (3), 1884-1895, 2009 | 156 | 2009 |
Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain F Du, F Navarro-Garcia, Z Xia, T Tasaki, A Varshavsky Proceedings of the National Academy of Sciences 99 (22), 14110-14115, 2002 | 129 | 2002 |
Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway JY An, JW Seo, T Tasaki, MJ Lee, A Varshavsky, YT Kwon Proceedings of the National Academy of Sciences 103 (16), 6212-6217, 2006 | 110 | 2006 |
UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy T Tasaki, ST Kim, A Zakrzewska, BE Lee, MJ Kang, YD Yoo, ... Proceedings of the National Academy of Sciences 110 (10), 3800-3805, 2013 | 86 | 2013 |
Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability C Meisenberg, PS Tait, II Dianova, K Wright, MJ Edelmann, N Ternette, ... Nucleic acids research 40 (2), 701-711, 2012 | 70 | 2012 |
Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway MJ Lee, K Pal, T Tasaki, S Roy, Y Jiang, JY An, R Banerjee, YT Kwon Proceedings of the National Academy of Sciences 105 (1), 100-105, 2008 | 59 | 2008 |
Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2 Y Yamamoto, T Tasaki, A Nakamura, H Iwata, A Kazusaka, FJ Gonzalez, ... Pharmacogenetics and Genomics 8 (1), 73-82, 1998 | 59 | 1998 |
Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems T Tasaki, R Sohr, Z Xia, R Hellweg, H Hortnagl, A Varshavsky, YT Kwon Journal of Biological Chemistry 282 (25), 18510-18520, 2007 | 56 | 2007 |
Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus M Taniguchi, T Tasaki, H Ninomiya, Y Ueda, K Kuremoto, S Mitsutake, ... Scientific reports 6 (1), 37829, 2016 | 45 | 2016 |
The N-end rule proteolytic system in autophagy ST Kim, T Tasaki, A Zakrzewska, YD Yoo, K Sa Sung, SH Kim, ... Autophagy 9 (7), 1100-1103, 2013 | 39 | 2013 |
Pseudorabies virus (PRV) early protein 0 activates PRV gene transcription in combination with the immediate-early protein IE180 and enhances the infectivity of PRV genomic DNA E Ono, S Watanabe, H Nikami, T Tasaki, H Kida Veterinary microbiology 63 (2-4), 99-107, 1998 | 38 | 1998 |
The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins ST Kim, YJ Lee, T Tasaki, J Hwang, MJ Kang, EC Yi, BY Kim, YT Kwon PLoS One 13 (8), e0202260, 2018 | 35 | 2018 |
Ocular effects of exposure to 40, 75, and 95 GHz millimeter waves M Kojima, Y Suzuki, K Sasaki, M Taki, K Wake, S Watanabe, M Mizuno, ... Journal of Infrared, Millimeter, and Terahertz Waves 39, 912-925, 2018 | 32 | 2018 |
Expression and characterization of dog CYP2D15 using baculovirus expression system T Tasaki, A Nakamura, S Itoh, K Ohashi, Y Yamamoto, M Masuda, H Iwata, ... The journal of biochemistry 123 (1), 162-168, 1998 | 22 | 1998 |
The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome ST Kim, YJ Lee, T Tasaki, SR Mun, J Hwang, MJ Kang, S Ganipisetti, ... Journal of Cell Science 131 (17), jcs217646, 2018 | 20 | 2018 |